Self-Amplifying RNA Vaccines Give Equivalent Protection against Influenza to mRNA Vaccines but at Much Lower Doses

Molecular Therapy - Tập 26 - Trang 446-455 - 2018
Annette B. Vogel1, Laura Lambert2, Ekaterina Kinnear2, David Busse2, Stephanie Erbar1, Kerstin C. Reuter3, Lena Wicke1, Mario Perkovic4, Tim Beissert4, Heinrich Haas1, Stephen T. Reece1, Ugur Sahin3, John S. Tregoning2
1BioNTech RNA Pharmaceuticals GmbH, An der Goldgrube 12, 55131 Mainz, Germany
2Mucosal Infection and Immunity Group, Section of Virology, Department of Medicine, St. Mary’s Campus, Imperial College London W2 1PG, UK
3BioNTech AG, An der Goldgrube 12, 55131 Mainz, Germany
4TRON GmbH, Freiligrathstraße 12, 55131 Mainz, Germany

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