3D true-phase polarity recovery with independent phase estimation using three-tier stacks based region growing (3D-TRIPS)

Haining Liu1, Gregory J. Wilson2, Niranjan Balu2, Jeffrey H. Maki2,3, Daniel S. Hippe2, Wei Wu4, Hiroko Watase5, Jinnan Wang2, Martin L. Gunn2, Chun Yuan1,2,6
1Department of Bioengineering, University of Washington, Seattle, USA
2Department of Radiology, University of Washington, Seattle, USA
3Department of Radiology, University of Colorado, Aurora, USA
4Department of Radiology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China
5Department of Surgery, University of Washington, Seattle, USA
6Department of Bioengineering, Tsinghua University, Beijing, China

Tóm tắt

A postprocessing technique termed 3D true-phase polarity recovery with independent phase estimation using three-tier stacks based region growing (3D-TRIPS) was developed, which directly reconstructs phase-sensitive inversion-recovery images without acquisition of phase-reference images. The utility of this technique is demonstrated in myocardial late gadolinium enhancement (LGE) imaging. A data structure with three tiers of stacks was used for 3D-TRIPS to directly achieve reliable region growing for successful background-phase estimation. Fifteen patients undergoing postgadolinium 3D phase-sensitive inversion recovery (PSIR) cardiac LGE magnetic resonance imaging (MRI) were recruited, and 3D-TRIPS LGE reconstructions were compared with standard PSIR. Objective voxel-by-voxel comparison was performed. Additionally, blinded review by two radiologists compared scar visibility, clinical acceptability, voxel polarity error, or groups and blurring. 3D-TRIPS efficiently reconstructed postcontrast phase-sensitive myocardial LGE images. Objective analysis showed an average 95% voxel-by-voxel agreement between 3D-TRIPS and PSIR images. Blinded radiologist review demonstrated similar image quality between 3D-TRIPS and PSIR reconstruction. 3D-TRIPS provided similar image quality to PSIR for phase-sensitive myocardial LGE MRI reconstruction. 3D-TRIPS does not require acquisition of a reference image and can therefore be used to accelerate phase-sensitive LGE imaging.

Tài liệu tham khảo

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