2017 Alzheimer's disease facts and figures
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This article describes the public health impact of Alzheimer's disease (AD), including incidence and prevalence, mortality rates, costs of care, and the overall impact on caregivers and society. The
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Fernando MS, Ince PG. MRC Cognitive Function and Ageing Neuropathology Study Group, 2004, Vascular pathologies and cognition in a population‐based cohort of elderly people, J Neurol Sci, 226, 13, 10.1016/j.jns.2004.09.004
Verrees M, 2004, Management of normal pressure hydrocephalus, Am Fam Physician, 70, 1071
National Down Syndrome Society. Available at:http://www.ndss.org/Down‐Syndrome/What‐Is‐Down‐Syndrome/. Accessed November 24 2016.
National Down Syndrome Society. An Introduction to Alzheimer's http://www.ndss.org/Resources/Aging‐Matters/Alzheimers‐Disease/An‐Introduction‐to‐Alzheimers‐Disease/. Accessed October 20 2016.
National Institutes of Health.National institute on Aging.Alzheimer's Dis People Down Syndr Fact Sheet. Available at:https://www.nia.nih.gov/alzheimers/publication/alzheimers‐disease‐people‐down‐syndrome. Accessed October 20 2016.
Alzheimer's Drug Discovery Foundation.What APOE Means for Your Health. Available at:http://www.alzdiscovery.org/cognitive‐vitality/what‐apoe‐means‐for‐your‐health. Accessed November 24 2016.
Institute of Medicine, 2015, Cognitive Aging: Progress in Understanding and Opportunity for Action
The Brain: Our Sense of Self.https://science.education.nih.gov/supplements/nih4/self/activities/activities_toc.html. Accessed November 24 2016.
SajeevG WeuveJ McQueenMB BlackerD.Diabetes.The AlzRisk Database. Alzheimer Research Forum. Available at:http://www.alzrisk.org. Accessed November 30 2016.
HarringtonM WeuveJ JacksonJW BlackerD.Physical Activity.The AlzRisk Database. Alzheimer Research Forum. Available at:http://www.alzrisk.org. Accessed November 30 2016.
TanZS SpartanoNL BeiserAS DeCarliC AuerbachSH Vasan RS et al.Physical activity brain volume and dementia risk: The Framingham Study.J Gerontol A Biol Sci Med Sci2016;doi:10.1093/gerona/glw130 [epub ahead of print]. Accessed November 30 2016.
Grzywacz JG, 2016, Workplace exposures and cognitive function during adulthood: Evidence from National Survey of Midlife Development and the O*NET, J Occup Environ Med, 58, 535, 10.1097/JOM.0000000000000727
Harris CD, 2013, Adult Participation in aerobic and muscle‐strengthening physical activities — United States, 2011, Morb Mortal Wkly Rep, 62, 326
Steptoe A, 2005, Aging, Health, and Public Policy
Karp A, 2005, Mental, physical and social components in leisure activities equally contribute to decrease dementia risk, Dement Geriatr Cogn Disord, 21, 65, 10.1159/000089919
Yates LA, 2016, Cognitive leisure activities and future risk of cognitive impairment and dementia: Systematic review and meta‐analysis, Int Psychogeriatr, 9, 1
Sanjeev G, 2016, Late‐life cognitive activity and dementia, Epidemiology, 27, 732, 10.1097/EDE.0000000000000513
Centers for Disease Control and Prevention.Get the Stats on Traumatic Brain Injury in the United States. Available at:http://www.cdc.gov/traumaticbraininjury/pdf/BlueBook_factsheet‐a.pdf. Accessed November 24 2016.
National Institutes of Health.Traumatic Brain Injury. Available at: http://www.nlm.nih.gov/medlineplus/traumaticbraininjury.html. Accessed November 24 2016.
Institute for Social Research, 2009, National Football League Player Care Foundation Study of NFL Retired Players
Groswasser Z, 2002, Quantitative imaging in late TBI. Part II: Cognition and work after closed and penetrating head injury: A report of the Vietnam Head Injury Study, Brain Inj, 16, 681, 10.1080/02699050110119835
Grossberg GT, 2010, The art of sharing the diagnosis and management of Alzheimer's disease with patients and caregivers: Recommendations of an expert consensus panel, Prim Care Companion J Clin Psychiatry, 12
McKhann GM, 2012, Alzheimer's Disease — Modernizing concept, biological diagnosis and therapy, 115, 10.1159/000335402
HeW GoodkindD KowalP.U.S. Census Bureau International Population Reports P95/16–1 An Aging World: 2015 U.S. Government Publishing Office Washington DC 2016. Available at:http://www.census.gov/content/dam/Census/library/publications/2016/demo/p95‐16‐1.pdf. Accessed November 24 2016.
Administration on Aging Administration for Community Living U.S. Department of Health and Human Services.A Profile Old Americans: 2015. Available at:http://www.aoa.acl.gov/aging_statistics/profile/2015/docs/2015‐Profile.pdf. Accessed November 24 2016.
Alzheimer's Association, 2006, Early‐Onset Dementia: A National Challenge, a Future Crisis
Unpublished data from the 2015 Behavioral Risk Factor Surveillance System survey(www.cdc.gov/brfss).Data were analyzed and provided to the Alzheimer's Association by the Healthy Aging Program Centers for Disease Control and Prevention (CDC).
Manly JJ, 2004, Critical perspectives on racial and ethnic differentials in health in late life, 95
Lines LM, 2014, Racial and ethnic disparities among individuals with Alzheimer's disease in the United States: A literature review
Unpublished tabulations based on data from the National 5% Sample Medicare Fee‐for‐Service Beneficiaries for 2014.Prepared under contract by Avalere Health 2016.
Manton KC, 2005, Declining prevalence of dementia in the U.S. elderly population, Adv Gerontol, 16, 30
DoblhammerG FinkA ZyllaS FritzeT WillekensF.Short‐term trends in German dementia prevalence incidence and mortality.Presentation Alzheimer's Assoc Int Conf; 2014.
MJPrince AWimo MGuerchet G‐CAli Y‐TWu MPrina.World Alzheimer Rep 2015: The Glob Impact Demen Anal Prevalence Incidence Cost Trends.2015
Ortman JM, 2014, An Aging Nation: The Older Population in the United States, Current Population Reports, P25–1140
Kochanek KD, 2016, Deaths: Final Data for 2014, Natl Vital Stat Rep, 65, 1
World Health Organization, 2004, International Statistical Classification of Diseases and Related Health Problems. 10th revision
Romero JP, 2014, Under reporting of dementia deaths on death certificates: A systematic review of population‐based cohort studies, J Alzheimers Dis, 41, 213, 10.3233/JAD-132765
National Center for Health Statistics, 2002, Deaths: Final Data for 2000. National Vital Statistics Reports
Tejada‐Vera B, 2013, Mortality from Alzheimer's disease in the United States: Data for 2000 and 2010. National Center for Health Statistics Data Brief, No. 116
Friedman EM, 2015, U.S. prevalence and predictors of informal caregiving for dementia, Health Aff, 34, 1637, 10.1377/hlthaff.2015.0510
Only Walmart: 2016 Annual Report. Available at:http://www.corporatereport.com/walmart/2016/ar/_pdf/WMT_2016AR.pdf. Accessed January 12 2017.
McDonald's Corporation Report 2015. Available at:http://corporate.mcdonalds.com/content/dam/AboutMcDonalds/Investors%202/2015%20Annual%20Report.pdf. Accessed November 24 2016.
KasperJD FreedmanVA SpillmanBC.Disability and Care Needs of Older Americans by Dementia Status: An Analysis of the 2011 National Health and Aging Trends Study.U.S. Department of Health and Human Services; 2014. Available at:http://aspe.hhs.gov/report/disability‐and‐care‐needs‐older‐americans‐dementia‐status‐analysis‐2011‐national‐health‐and‐aging‐trends‐study. Accessed November 24 2016.
BouldinED AndresenE.Caregiving Across the United States: Caregivers of Persons with Alzheimer's Disease or Dementia in 8 States and the District of Columbia.Data 2009 2010 Behav Risk Factor Surveill Syst. Available at:http://www.alz.org/documents_custom/public‐health/2009‐2010‐combined‐caregiving.pdf. Accessed November 24 2016.
National Alliance for Caregiving and AARP.Caregiving in the U.S.: Unpublished data analyzed under contract for the Alzheimer's Association.2016
National Alliance for Caregiving and United Hospital Fund.Young Caregivers in the U.S.: Report of Findings; September 2005. Available at:www.caregiving.org/data/youngcaregivers.pdf. Accessed December 14 2016.
National Alliance for Caregiving and AARP.Caregiving in the U.S.: Unpublished data analyzed under contract for the Alzheimer's Association; 2009.
Alzheimer's Association.2014 Alzheimer's Disease Facts and Figures.Spec Rep Women Alzheimer's Dis. Available at:https://www.alz.org/downloads/Facts_Figures_2014.pdf. Accessed November 24 2016.
National Alliance for Caregiving and AARP.Caregiving in the U.S. (2015). Available at:http://www.caregiving.org/wp‐content/uploads/2015/05/2015_CaregivingintheUS_Final‐Report‐June‐4_WEB.pdf. Accessed November 24 2016.
SpillmanB WolffJ FreedmanVA KasperJD.Informal Caregiving for Older Americans: An Analysis of the 2011 National Health and Aging Trends Study. Available at:https://aspe.hhs.gov/report/informal‐caregiving‐older‐americans‐analysis‐2011‐national‐study‐caregiving. Accessed January 12 2017.
Liu W, 2009, Aging families and caregiving, 85
Goren A, 2016, Impact of caring for persons with Alzheimer's disease or dementia on caregivers' health outcomes: Findings from a community based survey in Japan, BMC Geriatr, 16, 122, 10.1186/s12877-016-0298-y
Alzheimer's Association.Facts and Figures. Special Report.2016
VitalianoPP UstundagO BorsonS.Objective and subjective cognitive problems among caregivers and matched non‐caregivers.Gerontologist2016;pii:gnv690 [epub ahead of print].
DasselKB CarrDC VitalianoP.Does caring for a spouse with dementia accelerate cognitive decline?Findings from the Health and Retirement Study. Gerontologist2015;pii:gnv148 [epub ahead of print].
Mausbach BT, 2014, Why does placement of persons with Alzheimer's disease into long‐term care improve caregivers' well‐being? Examination of psychological mediators, Psychol Aging, 29, 776, 10.1037/a0037626
Peng H‐L, 2012, Sleep disturbance in family caregivers of individuals with dementia: A review of the literature, Perspect Psychiatr C, 49, 135, 10.1111/ppc.12005
MetLife Mature Market Institute.The MetLife Study of Alzheimer's Disease: The Caregiving Experience; August 2006. Available at:https://www.metlife.com/assets/cao/mmi/publications/studies/mmi‐alzheimers‐disease‐caregiving‐experience‐study.pdf. Accessed November 24 2016.
Maslow K, 2012, Translating Innovation to Impact: Evidence‐Based Interventions to Support People with Alzheimer's Disease and their Caregiver at Home and in the Community
Rosalynn Carter Institute for Caregiving.Caregiver Intervention Database. Available at:http://www.rosalynncarter.org/caregiver_intervention_database/. Accessed November 24 2016.
Menne HL, 2014, Statewide implementation of “reducing disability in Alzheimer's disease”: Impact on family caregiver outcomes, J Gerontol Soc Work, 57, 626, 10.1080/01634372.2013.870276
MenneHL BassDM JohnsonJD KearneyKR BollinS TeriL.Program components and outcomes of individuals with dementia: Results from the replication of an evidence‐based program.J Appl Gerontol2015;pii:0733464815591212 [epub ahead of print].
Primetica B, 2015, Evidence‐Based Program replication: Translational activities, experiences, and challenges, J Appl Gerontol, 34, 652, 10.1177/0733464813508888
Boots LM, 2015, A systematic review of internet‐based supportive interventions for caregivers of patients with dementia, Int J Geriatr Psychiatry, 29, 331, 10.1002/gps.4016
Zarit SH, 2009, Aging families and caregiving, 131
Hicken BL, 2016, Supporting caregivers of rural veterans electronically (SCORE), J Rural Health
Khatutsky G, 2011, Understanding direct care workers: A snapshot of two of America's most important jobs: Certified nursing assistants and home health aides
Jones AL, 2009, The National Nursing Home Survey: 2004 Overview, Vital Health Stat 13, 167, 1
Kramer NA, 2000, Professional psychology in long‐ term care, 227
Institute of Medicine, 2008, Retooling for an Aging America: Building the Health Care Workforce
ElvishR BurrowS CawleyR HarneyK PillingM GregoryJ et al.‘Getting to know me’: The second phase roll‐out of a staff training programme for supporting people with dementia in general hospitals.Dementia (London)2016;pii:1471301216634926 [epub ahead of print].
Bray J, 2015, Enabling hospital staff to care for people with dementia, Nurs Old People, 27, 29, 10.7748/nop.27.10.29.s21
Eldercare Workforce Alliance, 2012, Geriatrics Workforce Shortage: A Looming Crisis for our Families
The American Geriatrics Society.The Geriatrics Workforce Policy Studies Center (GWPS). Available at:http://www.americangeriatrics.org/advocacy_public_policy/gwps/gwps_faqs/id:3188. Accessed November 24 2016.
SadakT WrightJ BorsonS.Managing Your Loved One's Health: Development of a new care management measure for dementia family caregivers.J Appl Gerontol2016;pii:0733464816657472 [epub ahead of print].
NoelMA KaluzynskiTS TempletonVH.Quality dementia care: Integrating caregivers into a chronic disease management model.J Appl Gerontol2015;pii:0733464815589986 [epub ahead of print].
National Academies of Sciences, Engineering, and Medicine, 2016, Families Caring for an Aging America
Gaugler JE, 2015, Family caregiving in the new normal
Unpublished tabulations based on data from the Medicare Current Beneficiary Survey for 2011.Prepared under contract by Avalere Health 2016.
BynumJPW MearaE ChangC‐H RhoadsJM.Our Parents Ourselves: Health Care for an Aging Population.A Report of the Dartmouth Atlas Project. The Dartmouth Institute for Health Policy & Clinical Practice. 2016.
Medicare.Glossary.Medicare: The Official U.S. Government Site for Medicare. Available at:http://www.medicare.gov/HomeHealthCompare/Resources/Glossary.html. Accessed November 24 2016.
Genworth.Cost Care Surv 2016: Summary of 2016 Survey Findings. Available at:https://www.genworth.com. Accessed October 1 2016.
Dwyer LL, 2014, Differences in Adult Day Services Center Participant Characteristics by Center Ownership: United States, 2012, NCHS Data Brief, No, 164
Dwyer LL, 2014, Differences in Adult Day Services Center Characteristics by Center Ownership: United States, 2012, NCHS Data Brief, No, 165
Mollica R, 2012, Assisted Living and Residential Care in the States in 2010
Sengupta M, 2015, Variation in Residential Care Community Resident Characteristics, by Size of Commnity: United States, 2014, NCHS Data Brief, No, 223
Caffrey C, 2015, Variation in Operating Characteristics of Residential Care Communities by Size of Community: United States, 2014, NCHS Data Brief, No, 222
U.S. Centers for Medicare & Medicaid Services.Nurs Home Data Compend 2015 Edition. Available at:https://www.cms.gov/Medicare/Provider‐Enrollment‐and‐Certification/CertificationandComplianc/Downloads/nursinghomedatacompendium_508‐2015.pdf. Accessed December 13 2016.
American Health Care Association.LTC Stats: Nursing Facility Operational Characteristics Report.Table 5: Nurs Facility Beds Dedicated Spec Care Units; 2014.
American Health Care Association.LTC Stats: Nursing Facility Operational Characteristics Report.Table 5: Nurs Facility Beds Dedicated Spec Care Units; 2013.
Bynum J, 2009, Characteristics, Costs, and Health Service Use for Medicare Beneficiaries with a Dementia Diagnosis: Report 1: Medicare Current Beneficiary Survey. Unpublished; provided under contract with the Alzheimer's Association
Eiken S, 2016, Medicaid Expenditures for Long‐Term Services and Supports (LTSS) in FY 2014: Managed LTSS Reached 15 Percent of LTSS Spending
MetLife Mature Market Institute, 2012, Market Survey of Long‐Term Care Costs: The 2012 MetLife Market Survey of Nursing Home, Assisted Living, Adult Day Services, and Home Care Costs
GJacobson CSwoope TNeuman.Income and Assets of Medicare Beneficiaries 2014‐2030. The Henry J. Kaiser Family Foundation Issue Brief.2015
U.S. Department of Health and Human Services.What is Long‐Term Care Insurance?Available at:http://longtermcare.gov/costs‐how‐to‐pay/what‐is‐long‐term‐care‐insurance/. Accessed November 272016.
U.S. Centers for Medicare & Medicaid Services.Your Medicare Coverage.Long‐Term Care. Available at:https://www.medicare.gov/coverage/long‐term‐care.html. Accessed December 20 2016.
Association of Health Insurance Plans.AHIP Statement on Long‐Term Care Insurance. Available at:https://www.ahip.org/ahip‐statement‐on‐long‐term‐care‐insurance/. Accessed 2016.
CohenMA.“The Current State of the Long‐Term Care Insurance Market.”Presented to the 14th Annual Intercompany Long‐Term Care Insurance Conference. March2014. Available at:http://iltciconf.org/2014/index_htm_files/44‐Cohen.pdf. Accessed November 24 2016.
HHS Office of the Assistant Secretary for Planning and Evaluation Office of Disability Aging and Long‐Term Care Policy.Long‐term Care Insurance ASPE Res Brief. 2012.
ReavesEL MusumeciM.Medicaid and Long‐Term Services and Supports: A Primer.Menlo Park Calif.: Kaiser Commission on Medicaid and the Uninsured Henry J. Kaiser Family Foundation;2015. Publication #8617–02.
Moody's Investors Service.Special Comment: Long‐Term Care Insurance: Sector Profile; 2012.
U.S. Centers for Medicare & Medicaid Services.Medicare Provider Utilization and Payment Data: Hospice Providers. Available at:https://www.cms.gov/Research‐Statistics‐Data‐and‐Systems/Statistics‐Trends‐and‐Reports/Medicare‐Provider‐Charge‐Data/Hospice.html. Accessed November 5 2016.
U.S. Centers for Medicare and Medicaid Services.Hospice Center. Available at:http://www.cms.gov/Medicare/Medicare‐Fee‐for‐Service‐Payment/Hospice/Medicare_Hospice_Data.html. Accessed November 24 2016.
Miller SC, 2001, Hospice enrollment and hospitalization of dying nursing home patients, Am J Med, 11, 38, 10.1016/S0002-9343(01)00747-1
Teno JM, 2013, Change in end‐of‐life care for Medicare beneficiaries: Site of death, place of care, and health care transitions in 2000, 2005, and 2009, JAMA, 390, 470, 10.1001/jama.2012.207624
Gilligan AM, 2013, Health disparities in cost of care in patients with Alzheimer's disease: An analysis across 4 state Medicaid populations, Am J Alzheimers Dis Other Dement, 28, 84, 10.1177/1533317512467679
Healthy People 2020.Dementias Including Alzheimer's Disease. Available at:http://www.healthypeople.gov/2020/topics‐objectives/topic/dementias‐including‐alzheimers‐disease/national‐snapshot. Accessed November 24 2016.
Amjad H, 2016, Continuity of care and health care utilization in older adults, JAMA Intern Med, 176, 1371, 10.1001/jamainternmed.2016.3553
U.S. Census Bureau.2014 National Population Projections: Downloadable Files. Available at:https://www.census.gov/population/projections/data/national/2014/downloadablefiles.html. Accessed 2016.
U.S. Census Bureau.National Population Projections for 2016 to 2020: Summary Tables. Available at:http://www.census.gov/population/projections/files/natproj/summary/np‐t4‐e.pdf. Accessed November 30 2016.
National Alliance for Caregiving and AARP Caregiving in the U.S. November 2009. Available at:http://assets.aarp.org/rgcenter/il/caregiving_09_fr.pdf. Accessed November 24 2016.
Amo PS, 1999, The economic value of informal caregiving, Health Aff, 18, 182, 10.1377/hlthaff.18.2.182
U.S. Department of Labor Bureau of Labor Statistics.Employment Hours Earnings Curr Employment Stat Surv.Series 10‐CEU 6562160008 Home Health Care Services (NAICS code 6216) Average Hourly Earnings July 2016. Available at:www.bls.gov/ces. Accessed January 14 2017.
Albert SM, 2010, The MetLife Study of working caregivers and employer health care costs
U.S. Centers for Medicare & Medicaid Services Center for Strategic Planning Health Expenditures by State of Residence 1991‐2009. Available at:https://www.cms.gov/mmrr/Downloads/MMRR2011_001_04_a03‐.pdf. Accessed November 30 2016.
Shriver M, 2010, The Shriver Report: A Woman's Nation Takes on Alzheimer's