13C n.m.r. spectra of steroids —a survey and commentary

Wiley - Tập 9 Số 8 - Trang 439-464 - 1977
John W. Blunt1, J. B. Stothers1
1Department of Chemistry, University of Western Ontario, London, Canada

Tóm tắt

Abstract

The literature on 13C n.m.r. examinations of steroids has been reviewed and the shielding data for over 400 examples are tubulated. The assignments for each compound have been considered and, where necessary, revised in the light of more recent evidence and for consistency throughout each series. The methods available for assignments are reviewed and, in many cases, illustrated with specific examples. The major practical features concerning 13C studies of steroids are discussed as a guide to the use of the technique. From the main body of shielding data, an extensive set of substituent effects has been generated to aid the examination of new systems. The utility and the limitations of these effects are described.

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