ARID1A Mutations in Cancer: Another Epigenetic Tumor Suppressor?

Versteege, 1998, Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer, Nature, 394, 203, 10.1038/28212

Biegel, 1999, Germ-line and acquired mutations of INI1 in atypical teratoid and rhabdoid tumors, Cancer Res, 59, 74

Wilson, 2011, SWI/SNF nucleosome remodellers and cancer, Nat Rev Cancer, 11, 481, 10.1038/nrc3068

Jones, 2010, Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma, Science, 330, 228, 10.1126/science.1196333

Wiegand, 2010, ARID1A mutations in endometriosis-associated ovarian carcinomas, N Engl J Med, 363, 1532, 10.1056/NEJMoa1008433

Wiegand, 2011, Loss of BAF250a (ARID1A) is frequent in high-grade endometrial carcinomas, J Pathol, 224, 328, 10.1002/path.2911

Guan, 2011, Mutation and loss of expression of ARID1A in uterine low-grade endometrioid carcinoma, Am J Surg Pathol, 35, 625, 10.1097/PAS.0b013e318212782a

Wang, 2011, Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer, Nat Genet, 43, 1219, 10.1038/ng.982

Zang, 2012, Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes, Nat Genet, 44, 570, 10.1038/ng.2246

Abe, 2012, ARID1A expression loss in gastric cancer: pathway-dependent roles with and without Epstein-Barr virus infection and microsatellite instability, Virchows Arch, 461, 367, 10.1007/s00428-012-1303-2

Guichard, 2012, Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma, Nat Genet, 44, 694, 10.1038/ng.2256

Fujimoto, 2012, Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators, Nat Genet, 44, 760, 10.1038/ng.2291

Huang, 2012, Exome sequencing of hepatitis B virus-associated hepatocellular carcinoma, Nat Genet, 10.1038/ng.2391

Mamo, 2012, An integrated genomic approach identifies ARID1A as a candidate tumor-suppressor gene in breast cancer, Oncogene, 31, 2090, 10.1038/onc.2011.386

Jones, 2012, Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types, Hum Mutat, 33, 100, 10.1002/humu.21633

Shain, 2012, Convergent structural alterations define SWItch/Sucrose NonFermentable (SWI/SNF) chromatin remodeler as a central tumor suppressive complex in pancreatic cancer, Proc Natl Acad Sci U S A, 109, E252, 10.1073/pnas.1114817109

Birnbaum, 2011, Genome profiling of pancreatic adenocarcinoma, Genes Chromosomes Cancer, 50, 456, 10.1002/gcc.20870

Gui, 2011, Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder, Nat Genet, 43, 875, 10.1038/ng.907

Treon, 2012, MYD88 L265P somatic mutation in Waldenstrom's macroglobulinemia, N Engl J Med, 367, 826, 10.1056/NEJMoa1200710

Wang, 2004, Expression of p270 (ARID1A), a component of human SWI/SNF complexes, in human tumors, Int J Cancer, 112, 636, 10.1002/ijc.20450

Nagl, 2007, Distinct mammalian SWI/SNF chromatin remodeling complexes with opposing roles in cell-cycle control, EMBO J, 26, 752, 10.1038/sj.emboj.7601541

Gao, 2008, ES cell pluripotency and germ-layer formation require the SWI/SNF chromatin remodeling component BAF250a, Proc Natl Acad Sci U S A, 105, 6656, 10.1073/pnas.0801802105

Luo, 2008, Highly parallel identification of essential genes in cancer cells, Proc Natl Acad Sci U S A, 105, 20380, 10.1073/pnas.0810485105

Zhang, 2012, Frequent low expression of chromatin remodeling gene ARID1A in breast cancer and its clinical significance, Cancer Epidemiol, 36, 288, 10.1016/j.canep.2011.07.006

Chen, 2005, Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis, Nature, 436, 725, 10.1038/nature03918

Berger, 2011, A continuum model for tumour suppression, Nature, 476, 163, 10.1038/nature10275

Dallas, 2000, The human SWI-SNF complex protein p270 is an ARID family member with non-sequence-specific DNA binding activity, Mol Cell Biol, 20, 3137, 10.1128/MCB.20.9.3137-3146.2000

Wilsker, 2005, Nomenclature of the ARID family of DNA-binding proteins, Genomics, 86, 242, 10.1016/j.ygeno.2005.03.013

Flores-Alcantar, 2011, Dynamics of expression of ARID1A and ARID1B subunits in mouse embryos and in cells during the cell cycle, Cell Tissue Res, 345, 137, 10.1007/s00441-011-1182-x

Beausoleil, 2004, Large-scale characterization of HeLa cell nuclear phosphoproteins, Proc Natl Acad Sci U S A, 101, 12130, 10.1073/pnas.0404720101

Martens, 2003, Recent advances in understanding chromatin remodeling by Swi/Snf complexes, Curr Opin Genet Dev, 13, 136, 10.1016/S0959-437X(03)00022-4

Phelan, 1999, Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits, Mol Cell, 3, 247, 10.1016/S1097-2765(00)80315-9

Wang, 2003, The SWI/SNF family of ATP-dependent chromatin remodelers: similar mechanisms for diverse functions, Curr Top Microbiol Immunol, 274, 143

Roberts, 2004, The SWI/SNF complex–chromatin and cancer, Nat Rev Cancer, 4, 133, 10.1038/nrc1273

Hargreaves, 2011, ATP-dependent chromatin remodeling: genetics, genomics and mechanisms, Cell Res, 21, 396, 10.1038/cr.2011.32

Dallas, 1998, p300/CREB binding protein-related protein p270 is a component of mammalian SWI/SNF complexes, Mol Cell Biol, 18, 3596, 10.1128/MCB.18.6.3596

Nie, 2000, A specificity and targeting subunit of a human SWI/SNF family-related chromatin-remodeling complex, Mol Cell Biol, 20, 8879, 10.1128/MCB.20.23.8879-8888.2000

Trotter, 2004, Reconstitution of glucocorticoid receptor-dependent transcription in vivo, Mol Cell Biol, 24, 3347, 10.1128/MCB.24.8.3347-3358.2004

Trotter, 2008, The HSA domain of BRG1 mediates critical interactions required for glucocorticoid receptor-dependent transcriptional activation in vivo, Mol Cell Biol, 28, 1413, 10.1128/MCB.01301-07

Inoue, 2002, Largest subunits of the human SWI/SNF chromatin-remodeling complex promote transcriptional activation by steroid hormone receptors, J Biol Chem, 277, 41674, 10.1074/jbc.M205961200

Nagl, 2005, The p270 (ARID1A/SMARCF1) subunit of mammalian SWI/SNF-related complexes is essential for normal cell cycle arrest, Cancer Res, 65, 9236, 10.1158/0008-5472.CAN-05-1225

Nagl, 2006, The c-myc gene is a direct target of mammalian SWI/SNF-related complexes during differentiation-associated cell cycle arrest, Cancer Res, 66, 1289, 10.1158/0008-5472.CAN-05-3427

Inoue, 2011, Target genes of the largest human SWI/SNF complex subunit control cell growth, Biochem J, 434, 83, 10.1042/BJ20101358

Hanahan, 2011, Hallmarks of cancer: the next generation, Cell, 144, 646, 10.1016/j.cell.2011.02.013

Guan, 2011, ARID1A, a factor that promotes formation of SWI/SNF-mediated chromatin remodeling, is a tumor suppressor in gynecologic cancers, Cancer Res, 71, 6718, 10.1158/0008-5472.CAN-11-1562

Varela, 2011, Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma, Nature, 469, 539, 10.1038/nature09639

Li, 2011, Inactivating mutations of the chromatin remodeling gene ARID2 in hepatocellular carcinoma, Nat Genet, 43, 828, 10.1038/ng.903

Stephens, 2012, The landscape of cancer genes and mutational processes in breast cancer, Nature, 486, 400, 10.1038/nature11017

Drost, 2010, BRD7 is a candidate tumour suppressor gene required for p53 function, Nat Cell Biol, 12, 380, 10.1038/ncb2038

Rodriguez-Nieto, 2011, Massive parallel DNA pyrosequencing analysis of the tumor suppressor BRG1/SMARCA4 in lung primary tumors, Hum Mutat, 32, E1999, 10.1002/humu.21415

Robinson, 2012, Novel mutations target distinct subgroups of medulloblastoma, Nature, 488, 43, 10.1038/nature11213

Li, 2010, Mammalian SWI/SNF–a subunit BAF250/ARID1 is an E3 ubiquitin ligase that targets histone H2B, Mol Cell Biol, 30, 1673, 10.1128/MCB.00540-09

Yamamoto, 2012, PIK3CA mutations and loss of ARID1A protein expression are early events in the development of cystic ovarian clear cell adenocarcinoma, Virchows Arch, 460, 77, 10.1007/s00428-011-1169-8

Dunaief, 1994, The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest, Cell, 79, 119, 10.1016/0092-8674(94)90405-7

Betz, 2002, Re-expression of hSNF5/INI1/BAF47 in pediatric tumor cells leads to G1 arrest associated with induction of p16ink4a and activation of RB, Oncogene, 21, 5193, 10.1038/sj.onc.1205706

Maeda, 2010, Clinicopathological significance of loss of ARID1A immunoreactivity in ovarian clear cell carcinoma, Int J Mol Sci, 11, 5120, 10.3390/ijms11125120

Katagiri, 2012, Loss of ARID1A expression is related to shorter progression-free survival and chemoresistance in ovarian clear cell carcinoma, Mod Pathol, 25, 282, 10.1038/modpathol.2011.161

Fadare, 2012, Does the loss of ARID1A (BAF-250a) expression in endometrial clear cell carcinomas have any clinicopathologic significance? A pilot assessment, J Cancer, 3, 129, 10.7150/jca.4140

Cornen, 2012, Mutations and deletions of ARID1A in breast tumors, Oncogene, 31, 4255, 10.1038/onc.2011.598

Popovic, 2012, Emerging epigenetic targets and therapies in cancer medicine, Cancer Discov, 2, 405, 10.1158/2159-8290.CD-12-0076