Vitamin B12serostatus in Colombian children and adult women: results from a nationally representative survey

Public Health Nutrition - Tập 18 Số 5 - Trang 836-843 - 2015
Oscar F. Herrán1, Julia B. Ward2, Eduardo Villamor2
11School of Nutrition and Dietetics,Faculty of Health,Industrial University of Santander,Carrera 32 No. 29-31,Office 304,Bucaramanga,Colombia.
22Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA

Tóm tắt

AbstractObjectiveVitamin B12deficiency is associated with many adverse health outcomes and is highly prevalent worldwide. The present study assesses the prevalence of vitamin B12deficiency and marginal deficiency in Colombian children and women and examines the sociodemographic correlates of serum vitamin B12concentrations in these groups.DesignCross-sectional, nationally representative survey.SettingColombia.SubjectsChildren <18 years old (n7243), pregnant women (n1781), and non-pregnant women 18–49 years old (n499).ResultsThe overall prevalence of vitamin B12deficiency (serum vitamin B12<148 pmol/l) and marginal deficiency (serum vitamin B12=148–221 pmol/l) was, respectively, 6·6 % (95 % CI 5·2 %, 8·3 %) and 22·5 % (95 % CI 21·1 %, 23·9 %). Pregnant women had the highest prevalence of deficiency (18·9 %; 95 % CI 16·6 %, 21·5 %) compared with non-pregnant adult women (18·5 %; 95 % CI 4·4 %, 53·1 %) and children (2·8 %; 95 % CI 2·3 % %, 3·3 %). In multivariable analyses among children, mean serum vitamin B12was positively associated with female sex (12 pmol/l higher compared with males;P=0·004), secondary or higher education of the household head (12 pmol/l higher compared with primary or less;P=0·009) and food security (21 pmol/l higher compared with severe food insecurity;P=0·003). In multivariable analyses among pregnant women, mean serum vitamin B12was positively associated with education of the household head and inversely associated with living in the National territories, Eastern or Pacific regions.ConclusionsThe prevalence of vitamin B12deficiency and marginal deficiency in Colombian women and children is substantial. The burden falls largely on adult women, those with lowest education and those living in the poorest, most rural regions of the country.

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Public Health Nutrition

Tập 18 Số 5

836-843

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