[18F]FDOPA PET/CT in Solid Pseudopapillary Tumor of the Pancreas: a Recurred Tumor Mimicking Splenosis

Joonhyung Gil1,2, Minseok Suh1,2, Hongyoon Choi1,2, Jin Chul Paeng1,2, Gi Jeong Cheon1,2, Keon Wook Kang1,2
1Department of Nuclear Medicine, Seoul National University Hospital, Seoul, Republic of Korea
2Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea

Tóm tắt

Solid pseudopapillary tumor (SPT) of the pancreas is a neoplasm with low malignant potential. It is often challenging to diagnose SPT due to its nonspecific clinical and radiological features, and [18F]FDOPA is effective in diagnosing SPT, particularly in differentiating SPT from benign conditions such as splenosis. A 55-year-old woman underwent distal pancreatectomy and splenectomy for histologically confirmed SPT. She was also initially diagnosed with splenosis. During follow-up, sizes of multiple nodular lesions were increased, raising the possibility of peritoneal seeding of SPT. For diagnosis, a spleen scan and SPECT/CT were performed using 99mTc-labeled damaged red blood cells, which showed no uptake in the peritoneal nodules. Subsequent [18F]FDOPA PET/CT revealed [18F]FDOPA-avidity of the nodules. The patient underwent tumor resection surgery, and the nodules were pathologically confirmed as SPT.

Tài liệu tham khảo

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