α2-Adrenoceptor Regulation of Blood Glucose Homeostasis
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Brede, 2004, Alpha2-adrenergic receptor subtypes - novel functions uncovered in gene-targeted mouse models, Biol Cell, 96, 343, 10.1016/j.biolcel.2004.03.006
Moura, 2006, Alpha2-adrenoceptor subtypes involved in the regulation of catecholamine release from the adrenal medulla of mice, Br J Pharmacol, 149, 1049, 10.1038/sj.bjp.0706950
Chan, 1997, Differential expression of alpha 2-adrenoceptor subtypes in purified rat pancreatic islet A- and B-cells, Cell Signal, 9, 71, 10.1016/S0898-6568(96)00096-4
Lacey, 1996, Expression of alpha 2- and beta-adrenoceptor subtypes in human islets of Langerhans, J Endocrinol, 148, 531, 10.1677/joe.0.1480531
Angel, 1990, Involvement of alpha-2 adrenergic receptor subtypes in hyperglycemia, J Pharmacol Exp Ther, 254, 877
Niddam, 1990, Pharmacological characterization of alpha-2 adrenergic receptor subtype involved in the release of insulin from isolated rat pancreatic islets, J Pharmacol Exp Ther, 254, 883
Peterhoff, 2003, Inhibition of insulin secretion via distinct signaling pathways in alpha2-adrenoceptor knockout mice, Eur J Endocrinol, 149, 343, 10.1530/eje.0.1490343
Hu, 2005, Proteomic exploration of pancreatic islets in mice null for the alpha2A adrenergic receptor, J Mol Endocrinol, 35, 73, 10.1677/jme.1.01764
Fagerholm, 2004, Altered glucose homeostasis in alpha2A-adrenoceptor knockout mice, Eur J Pharmacol, 505, 243, 10.1016/j.ejphar.2004.10.023
Regard, 2007, Probing cell type-specific functions of Gi in vivo identifies GPCR regulators of insulin secretion, J Clin Invest, 117, 4034
Savontaus, 2008, Reduced blood glucose levels, increased insulin levels and improved glucose tolerance in alpha2A-adrenoceptor knockout mice, Eur J Pharmacol, 578, 359, 10.1016/j.ejphar.2007.09.015
Klein, 1985, Transdermal clonidine therapy in elderly mild hypertensives: effects on blood pressure, plasma norepinephrine and fasting plasma glucose, J Hypertens Suppl, 3, S81
Lattermann, 2001, Low dose clonidine premedication accentuates the hyperglycemic response to surgery, Can J Anaesth, 48, 755, 10.1007/BF03016690
Parsons, 1970, Antihypertensive effect of a new imidazoline compound (clonidine) and chlorthalidone, individually and in combination, Am J Cardiol, 26, 258, 10.1016/0002-9149(70)90792-7
Barbieri, 1981, Oral glucose tolerance and insulin response after one week’s clonidine treatment in hypertensive patients, Acta Diabetol Lat, 18, 59, 10.1007/BF02056107
Guthrie, 1983, Clonidine in patients with diabetes and mild hypertension, Clin Pharmacol Ther, 34, 713, 10.1038/clpt.1983.239
Kimber, 2001, Age- and gender-related growth hormone responses to intravenous clonidine in healthy adults, Growth Horm IGF Res, 11, 128, 10.1054/ghir.2001.0199
Joffe, 1986, Clonidine and the hormonal responses to graded exercise in healthy subjects, Horm Res, 23, 136, 10.1159/000180308
Nishina, 1998, Effects of oral clonidine premedication on plasma glucose and lipid homeostasis associated with exogenous glucose infusion in children, Anesthesiology, 88, 922, 10.1097/00000542-199804000-00011
Giugliano, 1998, Hemodynamic and metabolic effects of transdermal clonidine in patients with hypertension and non-insulin-dependent diabetes mellitus, Am J Hypertens, 11, 184, 10.1016/S0895-7061(97)00319-1
Nilsson-Ehle, 1988, Lipoproteins and metabolic control in hypertensive type II diabetics treated with clonidine, Acta Med Scand, 224, 131, 10.1111/j.0954-6820.1988.tb16750.x
Stornello, 1986, Humoral and hemodynamic effects of nitrendipine versus clonidine in patients with essential hypertension, Clin Ther, 8, 510
Burge, 2000, Low-dose epinephrine supports plasma glucose in fasted elderly patients with type 2 diabetes, Metabolism, 49, 195, 10.1016/S0026-0495(00)91273-3
Devedjian, 2000, Transgenic mice overexpressing alpha2A-adrenoceptors in pancreatic beta-cells show altered regulation of glucose homeostasis, Diabetologia, 43, 899, 10.1007/s001250051467
Hamamdzic, 1995, Regulation of alpha 2-adrenergic receptor expression and signaling in pancreatic beta-cells, Am J Physiol, 269, E162
Davani, 2004, Aged transgenic mice with increased glucocorticoid sensitivity in pancreatic beta-cells develop diabetes, Diabetes, 53, S51, 10.2337/diabetes.53.2007.S51
Rosmond, 2002, A C-1291G polymorphism in the alpha2A-adrenergic receptor gene (ADRA2A) promoter is associated with cortisol escape from dexamethasone and elevated glucose levels, J Intern Med, 251, 252, 10.1046/j.1365-2796.2002.00961.x
Boesgaard, 2010, Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people, Diabetologia, 53, 1647, 10.1007/s00125-010-1753-5
Dupuis, 2010, New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk, Nat Genet, 42, 105, 10.1038/ng.520
Rosengren, 2010, Overexpression of alpha2A-adrenergic receptors contributes to type 2 diabetes, Science, 327, 217, 10.1126/science.1176827
Small, 2006, Complex haplotypes derived from noncoding polymorphisms of the intronless alpha2A-adrenergic gene diversify receptor expression, Proc Natl Acad Sci USA, 103, 5472, 10.1073/pnas.0601345103
Berlin, 1994, Reduction of hyperglycemia after oral glucose load by the new alpha 2-adrenergic receptor antagonist SL 84.0418 in healthy subjects, Clin Pharmacol Ther, 55, 338, 10.1038/clpt.1994.35
Buse, 1970, Effect of alpha-adrenergic blockade on insulin secretion in man, Metabolism, 19, 219, 10.1016/0026-0495(70)90055-7
Kawazu, 1987, Studies of midaglizole (DG-5128). A new type of oral hypoglycemic drug in healthy subjects, Diabetes, 36, 216, 10.2337/diabetes.36.2.216
Ortiz-Alonso, 1991, Effect of an oral alpha 2-adrenergic blocker (MK-912) on pancreatic islet function in non-insulin-dependent diabetes mellitus, Metabolism, 40, 1160, 10.1016/0026-0495(91)90210-N
Robertson, 1976, A role for alpha-adrenergic receptors in abnormal insulin secretion in diabetes mellitus, J Clin Invest, 57, 791, 10.1172/JCI108338
Schmidt, 1997, Acute alpha 2 blockade by idazoxan increases insulin and lowers plasma glucose during positron emission tomography, Psychopharmacol Bull, 33, 253
Ribes, 1984, In vivo stimulation of pancreatic hormone secretion by norepinephrine infusion in the dog, Am J Physiol, 246, E339
Östenson, 1988, Alpha 2-adrenoceptor blockade does not enhance glucose-induced insulin release in normal subjects or patients with noninsulin-dependent diabetes, J Clin Endocrinol Metab, 67, 1054, 10.1210/jcem-67-5-1054
Natali, 1998, Effects of acute alpha 2-blockade on insulin action and secretion in humans, Am J Physiol, 274, E57
Sciberras, 1994, The effects of a peripherally selective alpha 2-adrenoceptor antagonist, MK-467, on the metabolic and cardiovascular response to exercise in healthy man, Br J Clin Pharmacol, 37, 39, 10.1111/j.1365-2125.1994.tb04236.x
Morgan, 2001, Imidazoline binding sites in the endocrine pancreas: can they fulfil their potential as targets for the development of new insulin secretagogues?, Curr Pharm Des, 7, 1413, 10.2174/1381612013397366
Efendic, 2002, Two generations of insulinotropic imidazoline compounds, Diabetes, 51, S448, 10.2337/diabetes.51.2007.S448
Fagerholm, 2008, Alpha2a-adrenoceptor antagonism increases insulin secretion and synergistically augments the insulinotropic effect of glibenclamide in mice, Br J Pharmacol, 154, 1287, 10.1038/bjp.2008.186
Khosravi, 2006, Control of environmental health and removal of rats by alpha2-adrenergic antagonist and potassium channel blocker, Iran J Environ Health Sci Eng, 3, 255
Berridge, 1992, Comparison of the effects of efaroxan and glibenclamide on plasma glucose and insulin levels in rats, Eur J Pharmacol, 213, 213, 10.1016/0014-2999(92)90684-V
Mourtada, 1997, Interactions between imidazoline compounds and sulphonylureas in the regulation of insulin secretion, Br J Pharmacol, 121, 799, 10.1038/sj.bjp.0701172
de Boer, 1996, The pharmacologic profile of mirtazapine, J Clin Psychiatry, 57, 19
Garcia-Sevilla, 1981, Alpha 2-adrenoreceptors on human platelets: selective labelling by [3H]clonidine and [3H]yohimbine and competitive inhibition by antidepressant drugs, Eur J Pharmacol, 74, 329, 10.1016/0014-2999(81)90052-2