Practice changing data and new developments in the management of prostate cancer – ASCO 2010memo - Magazine of European Medical Oncology - Tập 3 - Trang 164-166 - 2012
M. De Santis, M. Bachner
In the 2010 ASCO meeting valuable information and even practice-changing results
for the medical treatment of castration resistant prostate cancer (CRPC) were
presented. Focus was put on bone-targeted treatment, chemotherapy for second
line use, combinations of standard chemotherapy with different new drugs and
data on a novel antiangiogenic compounds. Denosumab was shown to be superior to
zoledro... hiện toàn bộ
Therapy with JAK 1/2 inhibitors for myelofibrosismemo - Magazine of European Medical Oncology - Tập 6 - Trang 109-113 - 2013
Franz Romeder, Richard Greil, Alexander Egle
Myelofibrosis (MF) is currently the myeloproliferative disorder with the most
severe prognosis. A mutation of the JAK2 (V617F) enzyme is present in about 65 %
of patients. Inhibition of JAK-kinases was therefore a proposed treatment for
the disease. The purpose of this article is to give an updated overview about
the recent developments in the therapy of MF with JAK-inhibitors. We did a
research t... hiện toàn bộ
Results of children with renal tumors treated in the Austrian–Hungarian Wilms Tumor Study 1989 and the International Society of Pediatric Oncology (SIOP) 93-01/GPOH trial in Austriamemo - Magazine of European Medical Oncology - Tập 5 - Trang 289-295 - 2012
Claudia Zimmermann, Ulrike Pötschger, Gabriele Amann, Ernst Horcher, Karin Dieckmann, Karoly Lakatos, Christian Urban, Herwig Lackner, Michael Höllwarth, Bernhard Meister, Roman Crazzolara, Georg Ebetsberger, Franz Martin Fink, Neil Jones, Agnes Gamper, Reinhard Moser, Reinhold Kerbl, Barbara Jauk, Walter Pobegen, Martin Henkel, Bernd Ausserer, Waltraud Friesenbichler, Judith Böhm, Norbert Graf, Wolfgang Holter, Helmut Gadner, Andreas Zoubek, Leo Kager
The overall outcome for children with nephroblastomas is excellent when treated
according to protocols that include surgery, chemotherapy, and, in selected
cases, radiotherapy. This study was conducted to provide population-based data
on Austrian children who had been treated in neoadjuvant nephroblastoma trials
between October 1988 and July 2001. One hundred and forty-eight children with
newly di... hiện toàn bộ
Highlights in surgery of brain tumoursmemo - Magazine of European Medical Oncology - Tập 3 - Trang 6-8 - 2010
V. V. Dolenc, I. J. Kocijančič, R. Pregelj
The largest possible and safe removal of the lesion (also malignant) is the best
first step of treatment. The extra-axial benign lesions do require the best
possible surgical treatment, ideally a complete resection of the lesion without
endangering the surrounding neural and/or vascular structures. The most frequent
extra-axial intracranial tumours are: pituitary tumours, craniopharyngiomas,
centr... hiện toàn bộ
The individualization of treatment based on molecular markersmemo - Magazine of European Medical Oncology - Tập 5 - Trang 251-252 - 2012
Vladimir M. Moiseyenko
Recent developments have revealed various decisive discoveries in individualized
oncology for many different entities—the individualization of treatment based on
molecular markers representing just one of those milestones. The implication of
epidermal growth factor receptor (EGFR) mutations for EGFR-tyrosine kinase
inhibitor (TKI) treatment, the definition of the HER2 status in breast cancer
and t... hiện toàn bộ
Immunotherapy in hepatocellular carcinomamemo - Magazine of European Medical Oncology - Tập 13 - Trang 218-222 - 2020
Stephanie Hametner-Schreil
Hepatocellular carcinoma (HCC) accounts for approximately 90% of primary liver
cancers. The prognosis remains poor—the 5‑year overall-survival (OS) is 12–18%,
all stages taken together. Systemic therapy has been limited to the use of
tyrosine kinase inhibitors for more than a decade. Now immune therapy has also
arrived in the field of systemic HCC treatment. Despite initial enthusiasm, the
respons... hiện toàn bộ
Cancer of unknown primary—state of the artmemo - Magazine of European Medical Oncology - - 2024
Thorsten Fuereder
SummaryThe Cancer of Unknown Primary (CUP) syndrome does not represent a single
clinical entity but comprises a diverse group of malignant tumors. CUP is
defined as a histologically confirmed metastatic malignant disease for which the
primary tumor cannot be identified after completing initial diagnostics.
Although its incidence has decreased, managing CUP patients remains a
significant clinical c... hiện toàn bộ