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GLUTAMINE METABOLISM IN LYMPHOCYTES: ITS BIOCHEMICAL, PHYSIOLOGICAL AND CLINICAL IMPORTANCE
Tập 70 Số 4 - Trang 473-489 - 1985
Glutamine is utilized at a high rate (fourfold higher than that of glucose) by
isolated incubated lymphocytes and produces glutamate, aspartate, lactate and
ammonia. The pathway for glutamine metabolism includes the reactions catalysed
by glutaminase, aspartate aminotransferase, oxoglutarate dehydrogenase,
succinate dehydrogenase, fumarase, malate dehydrogenase and phosphoenolpyruvate
carboxykinas...
ROLE OF ACTIVITY‐INDUCED THERMOGENESIS IN TWENTY‐FOUR HOUR ENERGY EXPENDITURE OF LEAN AND GENETICALLY OBESE (OB/OB) MICE
Tập 72 Số 4 - Trang 549-559 - 1987
The contribution made by spontaneous physical activity to 24 h energy
expenditure has been assessed in lean and ob/ob mice living at 28°C.
Measurements were made in young animals when the ob/ob mice were the same body
weight as their lean littermates, and again when they were adult and the ob/ob
mice were twice as heavy as their littermates.In the young ob/ob mice, not only
was 24 h heat productio...
FACTORS DETERMINING THE DIGESTIVE EFFICIENCY OF THE DOMESTICATED DONKEY (EQUUS ASINUS ASINUS)
Tập 74 Số 1 - Trang 1-6 - 1989
Factors determining the digestive efficiency of donkeys were studied in animals
fed either a low quality roughage (wheat straw: 77·1% neutral detergent fibre,
2·8% crude protein) or a high quality forage (alfalfa hay: 47·5% neutral
detergent fibre, 22·7% crude protein). The neutral detergent fibre (NDF) intake
when fed wheat straw was 1693 ± 268 g animal−1 day−1, 10% higher than when fed
alfalfa h...
GROWTH AND SYNAPSE FORMATION BY IDENTIFIED LEECH NEURONES IN CULTURE: A REVIEW
Tập 74 Số 6 - Trang 965-973 - 1989
Within hours after identified neurones have been isolated from the CNS of the
leech, they begin to sprout and to form synapses. Electrical recordings made by
loose‐patch clamp show that the tip of the isolated neurone has distinct
properties with a high density of sodium channels. Neurites grow out from this
tip after about 30 min and continue to grow for the next few days. The extent of
growth, t...
MECHANISMS RESISTING FATIGUE IN ISOMETRICALLY CONTRACTING HUMAN SKELETAL MUSCLE
Tập 73 Số 6 - Trang 903-914 - 1988
Human adductor pollicis was fatigued during circulatory occlusion by
supramaximal stimulation via the ulnar nerve using intermittent trains of
stimuli in ascending (1, 10, 20, 50 and 100 Hz) and descending (100, 50, 20, 10
and 1 Hz) frequencies to investigate the contribution of relaxation rate slowing
and post‐tetanic potentiation (PTP) to fatigue resistance. At 50 and 100 Hz
force was initially ...
TOLBUTAMIDE REVERSES HYPOXIC PULMONARY VASOCONSTRICTION IN ISOLATED RAT LUNGS
Tập 74 Số 6 - Trang 959-962 - 1989
We have investigated the effects of tolbutamide on the hypoxic vasoconstriction
of isolated, perfused rat lungs. We did this because lowered ATP may link
hypoxia and constriction, and tolbutamide mimics the effects of ATP in other
tissues by blocking ATP‐sensitive potassium (ATP‐K) channels. Pulmonary
vasoconstriction, induced by lowering the oxygen of the gas ventilating the
lungs from 95 to 2 %,...
CENTRALLY INJECTED ATRIAL NATRIURETIC FACTOR INHIBITS ANGIOTENSIN‐ AND OSMOTICALLY‐INDUCED DRINKING IN PIGS
Tập 73 Số 6 - Trang 1009-1012 - 1988
Atrial natriuretic factor 5‐28 (atriopeptin III, APIHI; 10 µg) injected into the
cerebral ventricles of young pigs 5 min before injection of either angiotensin
II (AII, 300 ng) or hypertonic NaCl (0·74 M) attenuated the subsequent drinking
responses to these dipsogens although the latency to the response was not
altered. The inhibition lasted for up to 4 days in the case of AII‐induced
drinking bu...