Wiley
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GLUTAMINE METABOLISM IN LYMPHOCYTES: ITS BIOCHEMICAL, PHYSIOLOGICAL AND CLINICAL IMPORTANCEGlutamine is utilized at a high rate (fourfold higher than that of glucose) by isolated incubated lymphocytes and produces glutamate, aspartate, lactate and ammonia. The pathway for glutamine metabolism includes the reactions catalysed by glutaminase, aspartate aminotransferase, oxoglutarate dehydrogenase, succinate dehydrogenase, fumarase, malate dehydrogenase and phosphoenolpyruvate carb... ...
Tập 70 Số 4 - Trang 473-489 - 1985
ROLE OF ACTIVITY‐INDUCED THERMOGENESIS IN TWENTY‐FOUR HOUR ENERGY EXPENDITURE OF LEAN AND GENETICALLY OBESE (OB/OB) MICEThe contribution made by spontaneous physical activity to 24 h energy expenditure has been assessed in lean and ob/ob mice living at 28°C. Measurements were made in young animals when the ob/ob mice were the same body weight as their lean littermates, and again when they were adult and the ob/ob mice were twic... ...
Tập 72 Số 4 - Trang 549-559 - 1987
FACTORS DETERMINING THE DIGESTIVE EFFICIENCY OF THE DOMESTICATED DONKEY (EQUUS ASINUS ASINUS)Factors determining the digestive efficiency of donkeys were studied in animals fed either a low quality roughage (wheat straw: 77·1% neutral detergent fibre, 2·8% crude protein) or a high quality forage (alfalfa hay: 47·5% neutral detergent fibre, 22·7% crude protein). The neutral detergent fibre (NDF) intake when fed wheat straw was 1693 ± 268 g animal−1 day...
Tập 74 Số 1 - Trang 1-6 - 1989
GROWTH AND SYNAPSE FORMATION BY IDENTIFIED LEECH NEURONES IN CULTURE: A REVIEWWithin hours after identified neurones have been isolated from the CNS of the leech, they begin to sprout and to form synapses. Electrical recordings made by loose‐patch clamp show that the tip of the isolated neurone has distinct properties with a high density of sodium channels. Neurites grow out from this tip after about 30 min and continue to grow for the next few days. The extent of g... ...
Tập 74 Số 6 - Trang 965-973 - 1989
MECHANISMS RESISTING FATIGUE IN ISOMETRICALLY CONTRACTING HUMAN SKELETAL MUSCLEHuman adductor pollicis was fatigued during circulatory occlusion by supramaximal stimulation via the ulnar nerve using intermittent trains of stimuli in ascending (1, 10, 20, 50 and 100 Hz) and descending (100, 50, 20, 10 and 1 Hz) frequencies to investigate the contribution of relaxation rate slowing and post‐tetanic potentiation (PTP) to fatigue resistance. At 50 and 100 Hz force was in... ...
Tập 73 Số 6 - Trang 903-914 - 1988
TOLBUTAMIDE REVERSES HYPOXIC PULMONARY VASOCONSTRICTION IN ISOLATED RAT LUNGSWe have investigated the effects of tolbutamide on the hypoxic vasoconstriction of isolated, perfused rat lungs. We did this because lowered ATP may link hypoxia and constriction, and tolbutamide mimics the effects of ATP in other tissues by blocking ATP‐sensitive potassium (ATP‐K) channels. Pulmonary vasoconstriction, induced by lowering the oxygen of the gas ventilating the lungs from 95... ...
Tập 74 Số 6 - Trang 959-962 - 1989
CENTRALLY INJECTED ATRIAL NATRIURETIC FACTOR INHIBITS ANGIOTENSIN‐ AND OSMOTICALLY‐INDUCED DRINKING IN PIGSAtrial natriuretic factor 5‐28 (atriopeptin III, APIHI; 10 µg) injected into the cerebral ventricles of young pigs 5 min before injection of either angiotensin II (AII, 300 ng) or hypertonic NaCl (0·74 M) attenuated the subsequent drinking responses to these dipsogens although the latency to the response was not altered. The inhibition lasted for up to 4 days in the case of AII‐induced dri... ...
Tập 73 Số 6 - Trang 1009-1012 - 1988