AbstractMany different human epithelial cell types have been immortalized by the
high‐risk human papillomaviruses (HPV)16 and HPV18. Only a few cell types have
been immortalized using either a high‐risk HPV E6 or E7 alone. Here, we report
reproducible immortalization of human uroepithelial cells (HUCs) from several
normal tissue donors after transformation with either HPV16 E6 or HPV16 E7. To
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