The identification and sequencing of the ob gene and its product, leptin, in
late 1994 opened new insights in the study of the mechanisms controlling body
weight and led to a surge of research activity. During this time, a considerable
body of knowledge regarding leptin's actions has been accumulated and the field
continues to expand rapidly. Currently there is particular interest in the
interacti... hiện toàn bộ
Jan Trøst Jørgensen, P. B. Andersen, Anders Rosholm, Nina H. Bjarnason
The precision of any given method for measurement of bone mineral density (BMD)
is important in relation to the interpretation of repeated measurements over
time, e.g. to monitor the course of suspected osteoporosis or follow the effect
of therapy. In the present study a new bone densitometer using the digital X‐ray
radiogrammetry (DXR) method (Pronosco X‐posure System™) is investigated with
respe... hiện toàn bộ
Hans Sjöholm, Kent Sahlin, Lars Edström, E. Hultman
Summary. A set up for electrical stimulation of the human quadriceps femoris
muscle and registration of tension is described. Normal values for the
frequency‐tension relations and relaxation time are presented. There was no
relationship between contraction characteristics and fibre type distribution.
Muscle tissue was sampled after electrical stimulation by percutaneous biopsy
technique. Phosphocr... hiện toàn bộ
José Alves-Guerreiro, J. Gareth Noble, Andrea S. Lowe, Deirdre Walsh
The current study was designed to examine the neurophysiological and hypoalgesic
effects of three types of electrical stimulation. Following approval by the
University’s Research Ethical Committee, healthy volunteers (n=40; 20 males and
20 females; age 20–40 years; mean age 26·18 years) were recruited and screened
for contraindications. Subjects were randomly allocated in equal numbers to the
foll... hiện toàn bộ
Myeong Soo Lee, Byung Gi Kim, Hwa Jeong Huh, Hoon Ryu, Hosub Lee, Hun‐Taeg Chung
To examine the physiological effects of Korean traditional Qi‐training, we
investigated the changes in blood pressure, heart and respiratory rates before,
during and after ChunDoSunBup (CDSB) Qi‐training. Twelve normal healthy CDSB
Qi‐trainees (19–37 years old; trained for 1·3 ± 0·2 years; 9 men and 3 women)
volunteered to participate in this study. Heart rate, respiratory rate, systolic
blood pre... hiện toàn bộ
Summary. Analyses of diffusion limitation of pulmonary O2 exchange have stressed
that alveolar PO2 (PAO2) is one of the most important factors to consider, but
recent reports suggest that PAO2 is important only insofar as it determines the
effective slope of the O2 dissociation curve. If this slope is the critical
factor, mixed venous PO2 (Pv̄o2) should also be important. This notion was
examined ... hiện toàn bộ
Voluntary negative intra‐thoracic pressure (Mueller manoeuvre) is known to
reduce arterial blood pressure (ABP). To investigate changes in cerebral blood
flow velocity (CBFV) during 15 s Mueller manoeuvres at –30 mmHg intra‐thoracic
pressure, 27 young (aged 21–31 years, group A) and 11 older (52–64 years,
group B) healthy adults were studied using transcranial Doppler and non‐invasive
ABP measurem... hiện toàn bộ
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