The Effect of Dopamine and Noradrenaline Antagonists on Amphetamine Induced Locomotor Activity in Mice and RatsWiley - Tập 33 Số 5-6 - Trang 385-399 - 1973
Z Roliński, Jørgen Scheel‐Krüger
Abstract: The effect of noradrenaline antagonists, aceperone, phenoxybenzamine and dihydroergotamine and neuroleptic drugs with dopamine receptor blocking properties, i. e. haloperidol, perphenazine, trifluperazine, spiramide and pimozide was tested on the locomotor and rearing activity induced by amphetamine, 2.5 mg/kg, in rats. In general it was found that the neu...... hiện toàn bộ
Distribution and Biotransformation of Methyl Mercuric Chloride in Different Tissues of MiceWiley - Tập 49 Số 1 - Trang 28-37 - 1981
Mandeep R. Mehra, BongKyoo Choi
Abstract: The distribution of 203Hg radioactivity has been studied in various organs of adult male and female mice from one hour to 21 days after treating with 203Hg‐labeled methyl mercuric chloride (MMC). The amount of methyl mercury (MeHg) and inorganic mercury (Hg) has also been determined by injecting single doses of non...... hiện toàn bộ
Disparate Serum Thioridazine Concentrations: Liquid Chromatography versus Radioreceptor AssayWiley - Tập 50 Số 1 - Trang 25-29 - 1982
Markku Linnoila, Jack E. Rosenblatt, Dilip V. Jeste, T. Skinner, William Z. Potter, Richard Jed Wyatt
Abstract: A radioceceptor and a liquid chromatographic assay quantitating serum thioridazine and its active metabolites yielded widely disparate results. The difference between the results of the two assays was relatively random. Contrary to earlier suggestions the radioreceptor assay may not be suitable for the measurement of all neuroleptics particularly when a co...... hiện toàn bộ
Effect of Nicotinic and Muscarinic Drugs on Amphetamine‐ and Apomorphine‐induced Circling Behaviour in RatsWiley - Tập 48 Số 2 - Trang 162-167 - 1981
Seppo Kaakkola
Abstract: The effect of drugs modulating the activity of nicotinic or muscarinic cholinergic receptors on the circling behaviour induced by amphetamine and apomorphine in rats with unilateral 6‐hydroxydopamine lesion of nigrostriatal dopaminergic pathway was studied. Nicotine (0.2 mg/kg subcutaneously) significantly increased amphetamine‐induced circling behaviour a...... hiện toàn bộ
Actinomycin D and Development of Tolerance to Morphine Analgesia in RatsWiley - Tập 32 Số 6 - Trang 519-524 - 1973
Torkell Jóanneson, William J. Steele
Abstract: Adult male (Wistar) rats were given an analgesic dose of morphine (10 mg/kg subcutaneously) with or without actinomycin D (10 μg/kg intraperitoneally) daily over a period of 3 or 4 days. The degree of analgesia was measured on the hot plate after each injection or after the last injection only. A high degree of tolerance to morphine analgesia was observed ...... hiện toàn bộ