Vascular Medicine

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Ankle—brachial index and hemostatic markers in the Atherosclerosis Risk in Communities (ARIC) study cohort
Vascular Medicine - Tập 12 Số 4 - Trang 267-273 - 2007
Laura M. Reich, Gerardo Heiss, Lori L. Boland, Alan T. Hirsch, Kenneth K. Wu, Aaron R. Folsom
To determine whether elevated levels of hemostatic and inflammatory markers [von Willebrand factor (vWF), fibrinogen, D-dimer, factor VII, factor VIII, PAI-1, tPA, beta-thromboglobulin (β-TG), CRP, and WBC count] are associated with increased peripheral arterial disease (PAD) prevalence, measured by low ABI, we studied 13,778 participants from the ARIC study in a cross-sectional analysis a...... hiện toàn bộ
Clinical evidence for anti-inflammatory effects of antiplatelet therapy in patients with atherothrombotic disease
Vascular Medicine - Tập 12 Số 2 - Trang 113-122 - 2007
Steven R. Steinhubl, Juan J. Badimón, Deepak L. Bhatt, Jean‐Marc Herbert, Thomas F. Lüscher
Recent advances in our understanding of cardiovascular disease have revealed that atherothrombotic events, such as myocardial infarction and ischemic stroke, are the end result of a complex inflammatory response to multifaceted vascular pathology. As well as initiating thrombus formation at the site of a ruptured atherosclerotic plaque, platelets play a key role in vascular inflammation, ...... hiện toàn bộ
Effect of aspirin on short-term outcomes in hospitalized patients with COVID-19
Vascular Medicine - Tập 26 Số 6 - Trang 626-632 - 2021
Aditya Sahai, Rohan Bhandari, Matthew Godwin, Thomas M. McIntyre, Mina K. Chung, Jean‐Pierre Iskandar, Hayaan Kamran, Essa Hariri, Anu Aggarwal, Robert Burton, Ankur Kalra, John R. Bartholomew, Keith R. McCrae, Ayman Elbadawi, James Bena, Lars G. Svensson, Samir Kapadia, Scott J. Cameron
Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 is an ongoing viral pandemic marked by increased risk of thrombotic events. However, the role of platelets in the elevated observed thrombotic risk in COVID-19 and utility of antiplatelet agents in attenuating thrombosis is unknown. We aimed to determine if the antiplatelet effect of aspirin may mitigate risk of myocardial infarction...... hiện toàn bộ
The role of optical coherence tomography in vascular medicine
Vascular Medicine - Tập 14 Số 1 - Trang 63-71 - 2009
Muhammad Farooq, Atul Khasnis, Arshad Majid, Mounzer Kassab
Abstract Optical coherence tomography (OCT) is an emerging imaging modality that provides high-resolution, microstructural information on atherosclerotic plaques in biological systems. Intracoronary OCT can identify thin-cap fibroatheroma and other vulnerable plaques that may be responsible for acute coronary events. These characteristics make OCT helpful in guiding coro...... hiện toàn bộ
Role of Endothelial Cells in Allograft Rejection
Vascular Medicine - Tập 2 Số 2 - Trang 105-114 - 1997
Marlene L. Rose
The immunological properties of endothelial cells suggest they perform a pivotal role in acute and chronic rejection following solid organ transplantation. Their constitutive expression of MHC class II molecules (which initiate allograft rejection by activating CD4 T cells) and accessory molecules allows them to present foreign antigen by both the direct and indirect route to the recipien...... hiện toàn bộ
Collagens in the progression and complications of atherosclerosis
Vascular Medicine - Tập 14 Số 1 - Trang 73-89 - 2009
Eser Adiguzel, Pamela J. Ahmad, Christopher Franco, Michelle P. Bendeck
Abstract Collagens constitute a major portion of the extracellular matrix in the atherosclerotic plaque, where they contribute to the strength and integrity of the fibrous cap, and also modulate cellular responses via specific receptors and signaling pathways. This review focuses on the diverse roles that collagens play in atherosclerosis; regulating the infiltration and...... hiện toàn bộ
Cardiovascular predictors for long-term mortality after EVAR for AAA
Vascular Medicine - Tập 16 Số 6 - Trang 422-427 - 2011
Tomas Ohrlander, Magnus Dencker, Nuno Dias, Anders Gottsäter, Stefan Acosta
The aim of this study was to assess cardiovascular predictors for all-cause long-term mortality in patients undergoing standard endovascular aneurysm repair (EVAR) for infrarenal abdominal aortic aneurysm (AAA). Consecutive patients treated with EVAR (Zenith® stent grafts; Cook) between May 1998 and February 2006 were prospectively enrolled in a computerized database,...... hiện toàn bộ
Beneficial effect of statins on total mortality in abdominal aortic aneurysm (AAA) repair
Vascular Medicine - Tập 22 Số 5 - Trang 406-410 - 2017
Sven R. Mathisen, Michael Abdelnoor
In this single center, retrospective cohort study we wished to compare early and total mortality for all patients treated for abdominal aortic aneurysms (AAA) with open surgery who were taking statins compared to those who were not. A cohort of 640 patients with AAA was treated with open surgery between 1999 and 2012. Patients were consecutively recruited from a source population of 390,0...... hiện toàn bộ
The pathophysiology of erectile dysfunction related to endothelial dysfunction and mediators of vascular function
Vascular Medicine - Tập 7 Số 3 - Trang 213-225 - 2002
Renke Maas, Edzard Schwedhelm, Jennifer Albsmeier, Rainer H. Böger
The incidence of erectile dysfunction increases with diabetes, hypertension, hypercholesterolaemia, cardiovascular disease and renal failure. All these conditions are associated with endothelial dysfunction. This review addresses the pathophysiology of erectile dysfunction with a special focus on new insights into nitric oxide (NO)-mediated pathways, oxidative stress and parallels to endo...... hiện toàn bộ
A systematic review of the sensitivity and specificity of the toe–brachial index for detecting peripheral artery disease
Vascular Medicine - Tập 21 Số 4 - Trang 382-389 - 2016
Peta Ellen Tehan, Derek Santos, Vivienne Chuter
The toe–brachial index (TBI) is used as an adjunct to the ankle–brachial index (ABI) for non-invasive lower limb vascular screening. With increasing evidence suggesting limitations of the ABI for diagnosis of vascular complications, particularly in specific populations including diabetes cohorts, the TBI is being used more widely. The aim of this review was to determine the sensitivity and...... hiện toàn bộ
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