Tumori
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Detection of somatostatin receptor subtypes 2 and 5 by somatostatin receptor scintigraphy and immunohistochemistry: Clinical implications in the diagnostic and therapeutic management of gastroenteropancreatic neuroendocrine tumors
Tumori - Tập 97 Số 5 - Trang 620-628 - 2011
Aims and background Somatostatin receptor scintigraphy (SRS) is the standard
method for the detection of somatostatin receptors (SSTRs). It is commonly used
in gastroenteropancreatic neuroendocrine tumor (GEP-NET) staging, and represents
the criterion of choice for treatment with somatostatin (SST) analogs.
Immunohistochemistry (IHC) was reported as a reliable method for the detection
of SSTRs wit...
Adenoid Cystic Carcinoma of the Breast.: Value of Immunohistochemical Study in Diagnosis
Tumori - Tập 77 Số 2 - Trang 130-135 - 1991
An immunohistochemical study of 5 cases of adenoid cystic carcinoma (ACC) of the
breast was performed with antibodies against keratin, EMA, vimentin, S-100
protein, alpha-smooth muscle actin and collagen IV. Results show the following:
1) ACC may be diagnosed and differentiated from ductal carcinoma (invasive or in
situ). The key to diagnosis is positivity within tumor masses of alpha-smooth
muscl...
Endometrioid Carcinoma of the Ovary: A Retrospective Analysis of 106 Cases
Tumori - Tập 84 Số 5 - Trang 552-557 - 1998
Aims and backgroundThis report retrospectively analyzes 106 cases of
endometrioid carcinoma of the ovary treated at the National Cancer Institute of
Milan from 1974 through December 1993. In 12 of the 106 cases (11.3%) a
synchronous carcinoma of the uterine body was observed.Methods and study
designOnly patients who had previously untreated disease were included in the
study. Patients with synchro...
Late Results after Sleeve or Wedge Lobectomies for Non-Small-Cell Lung Carcinoma
Tumori - Tập 74 Số 1 - Trang 71-73 - 1988
From January 1971 to June 1983, 35 lobectomies with bronchoplastic procedures
for invasive non-small-cell lung carcinoma were performed. Sleeve lobectomy was
carried out in 21 cases, wedge lobectomy in 11, and upper sleeve bilobectomy in
3. There were 23 stage I, 10 stage II, and 2 stage IIIa tumors. Completion
pneumonectomy was required in 1 case for anastomotic fistula and in 2 for
atelectasis o...
Peritoneal Cystic Mesothelioma: A Case Series
Tumori - Tập 89 Số 1 - Trang 31-35 - 2003
Background Cystic peritoneal mesothelioma is a rare disease associated with a
favorable short-term prognosis. Longer follow-up documenting a persistence of
symptoms and a high rate of recurrence after debulking surgery along with an
uncertain natural history prompt a re-evaluation of prior treatment
recommendations. No prior long-term clinical study of these patients is
available. Methods The expe...
Thin-Walled Cysts as a Pathognomonic CT Finding in Cystic Mesothelioma
Tumori - Tập 94 Số 1 - Trang 14-18 - 2008
AimCystic mesothelioma is a rare disease that results in abdominal distention
and poorly defined abdominal pain. Diagnosis has always been made by tissue
biopsy rather than by radiologic studies.Materials and methodsOur experience
with 7 patients with cystic mesothelioma includes 4 patients who had not had
prior surgery before the performance of a high resolution CT scan. A special
review of the r...
Medical Management of Colorectal Carcinomas
Tumori - Tập 80 Số 1 - Trang 1-11 - 1994
Current information on the medical treatment of colorectal cancer was reviewed
after a search of the literature through Medline. Publications from 1984 to
present were surveyed. Appropriate adjuvant therapy increases overall survival
and disease-free intervals. The treatment modalities of unresectable or
metastatic tumors are disappointing, with at best 40% of patients experiencing
short-lasting r...
Gemcitabine and Cisplatin Treatment of Advanced-Stage Non-Small-Cell Lung Cancer in Patients Given Cisplatin on Day 8
Tumori - Tập 94 Số 4 - Trang 474-480 - 2008
Aims and Background Gemcitabine and cisplatin treatment were administered to
patients with advanced-stage, non-small-cell lung cancer. During phase II
studies, the treatment is performed using a 28-day cycle, with gemcitabine
administered on days 1, 8, and 15. Although it is advised that cisplatin not be
administered on the first day, gemcitabine and cisplatin treatment is usually
performed using ...
Ovarian Function Suppression with the Gonadotrophin-Releasing Hormone (GnRH) Analogue Goserelin in Premenopausal Advanced Breast Cancer
Tumori - Tập 80 Số 1 - Trang 28-32 - 1994
Aims and background Goserelin is a gonadotrophin-releasing hormone (GnRH)
analogue that induces the suppression of gonadal steroidogenesis, and it could
therefore be a medical alternative to irreversible surgical castration. We
report the clinical and endocrine results from 40 goserelin-treated
premenopausal patients with advanced breast cancer. Methods A depot formulation
of the drug (3.6 mg s.c....
From Conventional to Stealth Liposomes a new Frontier in Cancer Chemotherapy
Tumori - Tập 89 Số 3 - Trang 237-249 - 2003
Many attempts have been made to achieve good selectivity to targeted tumor cells
by preparing specialized carrier agents that are therapeutically profitable for
anticancer therapy. Among these, liposomes are the most studied colloidal
particles thus far applied in medicine and in particular in antitumor therapy.
Although they were first described in the 1960s, only at the beginning of 1990s
did th...
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