Tumor Biology

Công bố khoa học tiêu biểu

* Dữ liệu chỉ mang tính chất tham khảo

Sắp xếp:  
Delivery of miR-155 to retinal pigment epithelial cells mediated by Burkitt’s lymphoma exosomes
Tumor Biology - Tập 37 - Trang 313-321 - 2015
Changshin Yoon, Jayoung Kim, Gabin Park, Seonghan Kim, Daejin Kim, Dae Young Hur, Bomi Kim, Yeong Seok Kim
Exosomes are extracellularly secreted vesicles ranging from 40 to 100 nm in diameter that are thought to play important roles in intercellular communication. Exosomes contain numerous proteins, RNA, and lipids that can affect the status of recipient cells under various pathological conditions. MicroRNAs (miRNAs) are small non-coding RNAs that play a major role in post-transcriptional gene silencin...... hiện toàn bộ
CXCR4, CXCL12 and the relative CXCL12-CXCR4 expression as prognostic factors in colon cancer
Tumor Biology - Tập 37 Số 6 - Trang 7441-7452 - 2016
Stanisavljević, Luka, Aßmus, Jörg, Storli, Kristian Eeg, Leh, Sabine Maria, Dahl, Olav, Myklebust, Mette Pernille
The CXCL12-CXCR4 axis is proposed to mediate metastasis formation. In this study, we examined CXCL12, CXCR4 and the relative CXCL12-CXCR4 expression as prognostic factors in two cohorts of colon cancer patients. Immunohistochemistry (IHC) and in situ hybridization (ISH) were used to study CXCR4, CXCL12 and relative CXCL12-CXCR4 expression in tissue microarrays. Our study included totally 596 patie...... hiện toàn bộ
Decreasing GSH and increasing ROS in chemosensitivity gliomas with IDH1 mutation
Tumor Biology - Tập 36 Số 2 - Trang 655-662 - 2015
Jinlong Shi, Bei Sun, Wei Shi, Houjuan Zuo, Daming Cui, Lei Ni, Jian Chen
Clinical significance of serum tenascin-c levels in epithelial ovarian cancer
Tumor Biology - Tập 35 - Trang 6777-6782 - 2014
Tastekin Didem, Tas Faruk, Karabulut Senem, Duranyildiz Derya, Serilmez Murat, Guveli Murat, Kaynur Oznur
Tenascin-C (TNC) is an extracellular matrix protein that is expressed at low levels in normal adult tissue but is highly expressed around many tumors including ovarian tumors. The objective of this study was to determine the clinical significance of the serum levels of TNC in epithelial ovarian cancer (EOC) patients. A total of 50 patients with a pathologically confirmed diagnosis of EOC were incl...... hiện toàn bộ
Clinical significance of microRNA expressions in diagnosing uterine cancer and predicting lymph node metastasis
Tumor Biology - - 2014
Changlong Hou, Guangming Tan, Shi‐Ting Feng
Association of TP53 gene polymorphisms with susceptibility of bladder cancer in Bangladeshi population
Tumor Biology - Tập 36 - Trang 6369-6374 - 2015
Md. Bayejid Hosen, Md. Abdus Salam, Md. Fakhrul Islam, Ashfaque Hossain, M Zakir Hossain Hawlader, Yearul Kabir
TP53 is considered to be the most frequently mutated gene in every forms of human cancer. The objective of this study was to evaluate the association of TP53 codon 72 and 248 polymorphisms with the susceptibility and severity of bladder cancer in Bangladeshi population. A case-control study on 102 bladder cancer patients and 140 control subjects was conducted. The genotype...... hiện toàn bộ
Expression of TGFβ-1 and EHD1 correlated with survival of non-small cell Lung cancer
Tumor Biology - - 2014
Yuanyuan Gao, Yan Wang, Lichun Sun, Qingwei Meng, Li Cai, Xiaoqun Dong
Transforming growth factor-β1 (TGFβ-1) signaling is regulated by endocytotic pathway. To clarify the prognostic value of TGFβ-1 and to verify the involvement of endocytosis in drug resistance, we examined the expression of TGFβ-1 and Eps15 homology domain 1 (EHD1) in non-small cell lung cancer (NSCLC) and its association with tumor characteristics and survival of patients with NSCLC. Expression of...... hiện toàn bộ
Survivin mRNA-circulating tumor cells predict treatment efficacy of chemotherapy and survival for advanced non-small cell lung cancer patients
Tumor Biology - Tập 35 Số 5 - Trang 4499-4507 - 2014
Yong-Jie Du, Jian Li, Wen Zhu, Yan Wu, Xinping Tang, Yi Wang, Yutian Hu
Role of ERCC1 variants in response to chemotherapy and clinical outcome of advanced non-small cell lung cancer
Tumor Biology - Tập 35 - Trang 4023-4029 - 2013
Shao-jun Huang, Yu-fei Wang, Zhi-yong Jin, Jia-yang Sun, Zhan-lin Guo
Excision repair cross-complementation group 1 (ERCC1) and xeroderma pigmentosum-F (XPF) in the nucleotide excision repair pathway have been effectively repairing DNA damage induced by chemotherapeutic agents. We conducted a cohort study to assess the associations of ERCC1 and XPF polymorphisms with response to platinum-based chemotherapy and clinical outcome of non-small-cell lung cancer (NSCLC). ...... hiện toàn bộ
Zoledronic acid increases cytotoxicity by inducing apoptosis in hormone and docetaxel-resistant prostate cancer cell lines
Tumor Biology - Tập 36 - Trang 779-786 - 2014
Umut Varol, Mustafa Degirmenci, Burcak Karaca, Harika Atmaca, Asli Kisim, Selim Uzunoglu, Canfeza Sezgin, Ulus Ali Sanli, Ruchan Uslu
Our aim was to investigate the possible synergistic/additive cytotoxic and apoptotic effects of combination of docetaxel and zoledronic acid (ZA), in PC-3 hormone-refractory prostate cancer cells (HRPC), as well as their docetaxel-resistant sublines. We established a docetaxel-resistant cell line (PC-3R) from PC-3 prostate cancer cells, by intermittent exposure to increasing concentrations of doce...... hiện toàn bộ
Tổng số: 3,529   
  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • 10