Treatments in Respiratory Medicine

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Respimat?? Soft Mist??? Inhaler versus Hydrofluoroalkane Metered Dose Inhaler
Treatments in Respiratory Medicine - Tập 4 Số 1 - Trang 53-61 - 2005
Wolfgang Schürmann, Sören Schmidtmann, Petra Moroni, Dan Massey, Mahmud Qidan
Pathogenesis and Management of Aspirin-Intolerant Asthma
Treatments in Respiratory Medicine - Tập 4 - Trang 325-336 - 2012
Yasushi Obase, Hiroto Matsuse, Terufumi Shimoda, Tari Haahtela, Shigeru Kohno
In 2–23% of adults with asthma, and rarely in children with asthma, aspirin (acetylsalicylic acid) and non-steroidal anti-inflammatory drugs (NSAIDs) cause asthma exacerbations. Within 3 hours of ingestion of aspirin/NSAIDs, individuals with aspirin-intolerant asthma (AIA) develop bronchoconstriction, often accompanied by rhinorrhea, conjunctival irritation, and scarlet flush. In severe cases, a s...... hiện toàn bộ
Matrix Metalloproteinases in the Pathogenesis of Asthma and COPD
Treatments in Respiratory Medicine - Tập 3 - Trang 17-27 - 2012
Ryujiro Suzuki, Yutaka Miyazaki, Kenzo Takagi, Keizo Torii, Hiroyuki Taniguchi
While asthma is an inflammatory disorder of the airways involving mediators released from mast cells and eosinophils, inflammation alone is insufficient to explain the chronic nature of the disease. Recent progress in the understanding of disease pathogenesis has revealed that airway remodeling, which is at least in part due to an excess of extracellular matrix (ECM) deposition in the airway wall,...... hiện toàn bộ
The Novolizer®: A Multidose Dry Powder Inhaler
Treatments in Respiratory Medicine - Tập 4 - Trang 70-70 - 2012
Peter Haidl
The Role of Antihistamines in Asthma Management
Treatments in Respiratory Medicine - - 2012
Andrew M. Wilson
Histamine is an important mediator in airway inflammation. It is elevated in the airways of asthmatic patients and is responsible for many of the pathophysiological features in asthma. Antihistamines block the actions of histamine and also have effects on inflammation which is independent of histamine-H1-receptor antagonism. Antihistamines have been shown to have bronchodilatory effects, effects o...... hiện toàn bộ
Lucinactant
Treatments in Respiratory Medicine - Tập 4 - Trang 139-145 - 2012
Marit D. Moen, Caroline M. Perry, Keri Wellington
▲ Lucinactant, formerly known as KL4 surfactant, is a novel synthetic lung surfactant containing phospholipids and an engineered peptide, sinapultide, which is designed to mimic the actions of human surfactant protein B. It has been developed for use in the prevention or treatment of respiratory distress syndrome (RDS), a common problem in premature infants, which results from a deficiency or degr...... hiện toàn bộ
Monotherapy versus Combination Therapy in Patients Hospitalized with Community-Acquired Pneumonia
Treatments in Respiratory Medicine - Tập 5 - Trang 371-383 - 2012
Martin Kolditz, Michael Halank, Gert Höffken
Current international guidelines for the management of community acquired pneumonia (CAP) recommend therapy with a β-lactam plus a macrolide or a ‘respiratory’ fluoroquinolone alone in patients hospitalized in a medical ward, and combination therapy with a β-lactam plus a macrolide or a fluoroquinolone in patients hospitalized in the intensive care unit. However, which of the available options sho...... hiện toàn bộ
Lung Volume Reduction Surgery
Treatments in Respiratory Medicine - Tập 4 Số 3 - Trang 211-213 - 2005
Joel D. Cooper
Spotlight on Cefditoren Pivoxil in Bacterial Infections
Treatments in Respiratory Medicine - Tập 4 - Trang 149-152 - 2012
Keri Wellington, Monique P. Curran
Cefditoren pivoxil (Spectracef®, Meiact®) is a third-generation oral cephalosporin with a broad spectrum of activity against pathogens, including both Gram-positive and -negative bacteria, and is stable to hydrolysis by many common β-lactamases. Cefditoren pivoxil is approved for use in the treatment of acute exacerbations of chronic bronchitis (AECB), mild-to-moderate community-acquired pneumonia...... hiện toàn bộ
Modeling and Remodeling of the Lung in Neonatal Chronic Lung Disease
Treatments in Respiratory Medicine - Tập 4 - Trang 347-359 - 2012
David G. Sweet, Henry L. Halliday
Neonatal chronic lung disease (CLD) is the major long-term pulmonary complication of preterm birth affecting about 20% of infants who need mechanical ventilation. CLD is the result of abnormal repair processes following inflammatory lung injury that lead to remodeling of the lung. Inflammation may be initiated by a variety of stimuli including mechanical ventilation, oxygen toxicity and infection....... hiện toàn bộ
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