Early Inflammatory Response in the Brain and Anesthesia Recovery Time Evaluation After Experimental Subarachnoid HemorrhageTranslational Stroke Research - Tập 10 - Trang 308-318 - 2018
K. Duris, J. Lipkova, Z. Splichal, T. Madaraszova, Michal Jurajda
The main objective was to evaluate, whether the subarachnoid hemorrhage (SAH)-associated early inflammatory response has focal or global character, i.e., whether areas distant to hematoma may be affected by an early inflammatory response. The second objective was to evaluate the association of anesthesia recovery time for basic reflexes/neurological functions with severity of SAH. SAH was induced ...... hiện toàn bộ
Blocking Hepatoma-Derived Growth Factor Attenuates Vasospasm and Neuron Cell Apoptosis in Rats Subjected to Subarachnoid HemorrhageTranslational Stroke Research - Tập 13 - Trang 300-310 - 2021
Chia-Li Chung, Chieh-Hsin Wu, Yu-Hua Huang, Shu-Chuan Wu, Chee-Yin Chai, Hung-Pei Tsai, Aij-Lie Kwan
Subarachnoid hemorrhage (SAH) is an important subcategory of stroke due to its unacceptably high mortality rate as well as the severe complications it causes, such as cerebral vasospasm, neurological deficits, and cardiopulmonary abnormality. Hepatoma-derived growth factor (HDGF) is a growth factor related to normal development and is involved in liver development and regeneration. This study expl...... hiện toàn bộ
Translational Research Using a Mouse Model of Intracranial AneurysmTranslational Stroke Research - Tập 5 - Trang 248-251 - 2013
Kosuke Wada, Hiroshi Makino, Kenji Shimada, Fumiaki Shikata, Atsushi Kuwabara, Tomoki Hashimoto
We have developed a mouse model of intracranial aneurysm that recapitulates key features of human intracranial aneurysms. In this model, spontaneous aneurysmal rupture occurs with a predictable time course. Aneurysmal rupture in this model can be easily detected by assessing neurological symptoms. Similar to human intracranial aneurysms, intracranial aneurysms in this model show an infiltration wi...... hiện toàn bộ
Bench to Cribside: the Path for Developing a NeuroprotectantTranslational Stroke Research - Tập 4 - Trang 258-277 - 2012
Nelina Ramanantsoa, Bobbi Fleiss, Myriam Bouslama, Boris Matrot, Leslie Schwendimann, Charles Cohen-Salmon, Pierre Gressens, Jorge Gallego
The consequences of perinatal brain injury include immeasurable anguish for families and substantial ongoing costs for care and support of effected children. Factors associated with perinatal brain injury in the preterm infant include inflammation and infection, and with increasing gestational age, a higher proportion is related to hypoxic–ischemic events, such as stroke and placental abruption. O...... hiện toàn bộ
Increased Number of Passes and Double Stent Retriever Technique Induces Cumulative Injury on Arterial Wall After Mechanical Thrombectomy in a Swine ModelTranslational Stroke Research - Tập 14 - Trang 425-433 - 2022
David Hernández, José Luis Cuevas, Laura Ludovica Gramegna, Manuel Requena, Carlos Piñana, Marta de Dios, Pilar Coscojuela, Marielle Esteves, Jiahui Li, Alberto Gil, Marc Ribó, Alejandro Tomasello
The number of stentriever passes during endovascular thrombectomy impacts clinical outcomes in acute ischemic stroke. Previous studies suggest that the simultaneous double stent retriever technique (DSRT) could improve the efficacy and reduce the number of passes. We aim to analyze the degree of vessel wall injury according to the number of passes and technique (single vs. simultaneous devices). H...... hiện toàn bộ