Translational Stroke Research

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Perihematoma Edema: A Potential Translational Target in Intracerebral Hemorrhage?
Translational Stroke Research - - 2015
Magdy Selim, Kevin N. Sheth
cPKCγ-Modulated Autophagy in Neurons Alleviates Ischemic Injury in Brain of Mice with Ischemic Stroke Through Akt-mTOR Pathway
Translational Stroke Research - Tập 7 - Trang 497-511 - 2016
Haiping Wei, Yun Li, Song Han, Shuiqiao Liu, Nan Zhang, Li Zhao, Shujuan Li, Junfa Li
We have reported that neuron-specific conventional protein kinase C (cPKC)γ is involved in the development of cerebral hypoxic preconditioning (HPC) and the neuroprotection against ischemic injuries, but its molecular mechanism is unclear. In this study, the adult and postnatal 24 h C57BL/6J wild-type (cPKCγ+/+) and cPKCγ knockout (cPKCγ−/−) mice were respectively used to establish the models of m... hiện toàn bộ
Co-ultramicronized Palmitoylethanolamide/Luteolin in the Treatment of Cerebral Ischemia: from Rodent to Man
Translational Stroke Research - Tập 7 - Trang 54-69 - 2015
Carlo Caltagirone, Carlo Cisari, Carlo Schievano, Rosanna Di Paola, Marika Cordaro, Giuseppe Bruschetta, Emanuela Esposito, Salvatore Cuzzocrea
Acute ischemic stroke, the most frequent cause of permanent disability in adults worldwide, results from transient or permanent reduction in regional cerebral blood flow and involves oxidative stress and inflammation. Despite the success of experimental animal models of stroke in identifying anti-inflammatory/neuroprotective compounds, translation of these putative neuroprotectants to human clinic... hiện toàn bộ
Vascular Disruption and the Role of Angiogenic Proteins After Spinal Cord Injury
Translational Stroke Research - Tập 2 - Trang 474-491 - 2011
Michelle T. L. Ng, Anthea T. Stammers, Brian K. Kwon
Spinal cord injuries (SCI) can result in devastating paralysis, for which there is currently no robustly efficacious neuroprotective/neuroregenerative treatment. When the spinal cord is subjected to a traumatic injury, the local vasculature is disrupted and the blood–spinal cord barrier is compromised. Subsequent inflammation and ischemia may then contribute to further secondary damage, exacerbati... hiện toàn bộ
Intra-hematomal White Matter Tracts Act As a Scaffold for Macrophage Infiltration After Intracerebral Hemorrhage
Translational Stroke Research - - 2021
Jingyin Chen, Sravanthi Koduri, Shuhui Dai, Yasunori Toyota, Ya Hua, Neeraj Chaudhary, Aditya S. Pandey, Richard F. Keep, Guohua Xi
Correction to: Comparative Studies of Cerebral Reperfusion Injury in the Posterior and Anterior Circulations After Mechanical Thrombectomy
Translational Stroke Research - Tập 13 - Trang 1056-1056 - 2022
Matthew M. Bower, Shuichi Suzuki, Kiarash Golshani, Li-Mei Lin, Mohammad Shafie, Hermelinda G. Abcede, Jay Shah, Dana Stradling, Wengui Yu
Critical Early Thrombolytic and Endovascular Reperfusion Therapy for Acute Ischemic Stroke Victims: a Call for Adjunct Neuroprotection
Translational Stroke Research - Tập 6 - Trang 345-354 - 2015
Paul A. Lapchak
Today, there is an enormous amount of excitement in the field of stroke victim care due to the recent success of MR. CLEAN, SWIFT PRIME, ESCAPE, EXTEND-IA, and REVASCAT endovascular trials. Successful intravenous (IV) recombinant tissue plasminogen activator (rt-PA) clinical trials [i.e., National Institute of Neurological Disorders and Stroke (NINDS) rt-PA trial, Third European Cooperative Acute ... hiện toàn bộ
Stroke Research in China over the Past Decade: Analysis of NSFC Funding
Translational Stroke Research - Tập 6 - Trang 253-256 - 2015
Lijun Zhu, Dongsheng He, Lijuan Han, Heqi Cao
We analyzed the projects and published studies funded by NSFC (National Natural Science Foundation of China) in the field of stoke. Further more, we searched the published papers supported by NSFC in the last decade using the keywords of "stroke" or "cerebrovascular disease" and analyzed the results according to the topics associated with the mechanisms of ischemic brain injury, novel techniques a... hiện toàn bộ
Comparative Studies of Cerebral Reperfusion Injury in the Posterior and Anterior Circulations After Mechanical Thrombectomy
Translational Stroke Research - Tập 13 - Trang 556-564 - 2022
Matthew M. Bower, Shuichi Suzuki, Kiarash Golshani, Li-Mei Lin, Mohammad Shafie, Hermelinda G. Abcede, Jay Shah, Dana Stradling, Wengui Yu
Cerebral reperfusion injury is the major complication of mechanical thrombectomy (MT) for acute ischemic stroke (AIS). Contrast extravasation (CE) and intracranial hemorrhage (ICH) are the key radiographical features of cerebral reperfusion injury. The aim of this study was to investigate CE and ICH after MT in the anterior and posterior circulation, and their effect on functional outcome. This is... hiện toàn bộ
Transplantation of Exercise-Induced Extracellular Vesicles as a Promising Therapeutic Approach in Ischemic Stroke
Translational Stroke Research - - 2023
Parsa Alehossein, Maryam Taheri, Pargol Tayefeh Ghahremani, Duaa Dakhlallah, Candice M. Brown, Tauheed Ishrat, Sanaz Nasoohi
Tổng số: 833   
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