Physiology of Iron Metabolism Tập 41 Số 3 - Trang 213-221 - 2014
Sophie Waldvogel‐Abramowski, Gérard Waeber, Christoph Gassner, Andreas Buser, Beat M. Frey, Bernard Favrat, Jean‐Daniel Tissot
A revolution occurred during the last decade in the comprehension of the
physiology as well as in the physiopathology of iron metabolism. The purpose of
this review is to summarize the recent knowledge that has accumulated, allowing
a better comprehension of the mechanisms implicated in iron homeostasis. Iron
metabolism is very fine tuned. The free molecule is very toxic; therefore,
complex regula... hiện toàn bộ
Platelet Interaction with Innate Immune Cells Tập 43 Số 2 - Trang 78-88 - 2016
Julia B. Kral‐Pointner, Waltraud C. Schrottmaier, Manuel Salzmann, Alice Assinger
Beyond their traditional role in haemostasis and thrombosis, platelets are
increasingly recognised as immune modulatory cells. Activated platelets and
platelet-derived microparticles can bind to leukocytes, which stimulates mutual
activation and results in rapid, local release of platelet-derived cytokines.
Thereby platelets modulate leukocyte effector functions and contribute to
inflammatory and ... hiện toàn bộ
The Rhesus Site Tập 41 Số 5 - Trang 357-363 - 2014
Franz F. Wagner, Willy A. Flegel
The Rhesus Site is a resource for information of the ‘Rhesus' blood group. It is
intended for specialists and non-specialists. The website details research in
the field relevant for transfusion medicine, immunohematology, and molecular
research. Link areas guide to important publications and to methodological
resources for Rhesus. Many data originally presented at The Rhesus Site have
been formall... hiện toàn bộ
Physiology and Pharmacology of Plerixafor Tập 40 Số 4 - Trang 237-245 - 2013
Simon P. Fricker
Autologous hematopoietic stem cell (HSC) transplantation is an important
therapeutic option for patients with non-Hodgkin's lymphoma and multiple
myeloma. The primary source of HSC is from the peripheral blood which requires
mobilization from the bone marrow. Current mobilization regimens include
cytokines such as G-CSF and/or chemotherapy. However not all patients mobilize
enough HSC to proceed t... hiện toàn bộ
Transfusion-Related Acute Lung Injury: The Work of DAMPs* Tập 40 Số 1 - Trang 3-13 - 2013
W. Land
Current notions in immunology hold that not only pathogen-mediated tissue injury
but any injury activates the innate immune system. In principle, this
evolutionarily highly conserved, rapid first-line defense system responds to
pathogen-induced injury with the creation of infectious inflammation, and
non-pathogen-induced tissue injury with ‘sterile’ tissue inflammation. In this
review, evidence ha... hiện toàn bộ