Toxicological Research

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Determination of Goitrogenic Metabolites in the Serum of Male Wistar Rat Fed Structurally Different Glucosinolates
Toxicological Research - - 2014
Eunji Choi, Ping Zhang, Hoonjeong Kwon
Pelargonium sidoides extract mediates nephrotoxicity through mitochondrial malfunction and cytoskeleton destabilization
Toxicological Research - Tập 39 - Trang 601-609 - 2023
Ju Young Lee, JuKyung Lee, Sung Ho Lee, Jeong Ho Hwang, Han Na Suh
We investigated the cytotoxic effect of Pelargonium sidoides extract on Madin–Darby canine kidney (MDCK) cells. P. sidoides extract decreased the cell viability in a dose dependent manner (> 0.2%). The extract of P. sidoides decreased the mitochondrial action potential, increased the number of reactive oxygen species (ROS) inside the cell, and caused nicotinamide adenine dinucleotide hydride (NADH...... hiện toàn bộ
Modulation of Apoptosis and Differentiation by the Treatment of Sulfasalazine in Rabbit Articular Chondrocytes
Toxicological Research - Tập 32 - Trang 115-121 - 2016
Won Kil Lee, Jin Seok Kang
This study was conducted to examine the cellular regulatory mechanisms of sulfasalazine (SSZ) in rabbit articular chondrocytes treated with sodium nitroprusside (SNP). Cell phenotype was determined, and the MTT assay, Western blot analysis and immunofluorescence staining of type II collagen was performed in control, SNP-treated and SNP plus SSZ (50~200 µg/mL) rabbit articular chondrocytes. Cellula...... hiện toàn bộ
Allele Frequencies of the Single Nucleotide Polymorphisms Related to the Body Burden of Heavy Metals in the Korean Population and Their Ethnic Differences
Toxicological Research - Tập 32 - Trang 195-205 - 2016
Sang-Yong Eom, Ji-Ae Lim, Yong-Dae Kim, Byung-Sun Choi, Myung Sil Hwang, Jung-Duck Park, Heon Kim, Ho-Jang Kwon
This study was performed to select single nucleotide polymorphisms (SNPs) related to the body burden of heavy metals in Koreans, to provide Korean allele frequencies of selected SNPs, and to assess the difference in allele frequencies with other ethnicities. The candidate-gene approach method and genome-wide association screening were used to select SNPs related to the body burden of heavy metals....... hiện toàn bộ
Analysis of 3-MCPD and 1,3-DCP in Various Foodstuffs Using GC-MS
Toxicological Research - Tập 31 - Trang 313-319 - 2015
Wooseok Kim, Yun A. Jeong, Jiwon On, Ari Choi, Jee-yeon Lee, Joon Goo Lee, Kwang-Geun Lee, Heesoo Pyo
This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0...... hiện toàn bộ
Hepatoprotective Effects of Polysaccharides Isolated from Phellinus gilvus Against Carbon Tetrachloride-induced Liver Injury in Rats
Toxicological Research - Tập 25 Số 1 - Trang 29-33 - 2009
Seung-Chun Park, Yong-Pil Cheon, Wha-Young Son, Man Hee Rhee, Tae‐Wan Kim, Jae-Chan Song, Kil-Soo Kim
Error-Prone and Error-Free Translesion DNA Synthesis over Site-Specifically Created DNA Adducts of Aryl Hydrocarbons (3-Nitrobenzanthrone and 4-Aminobiphenyl)
Toxicological Research - Tập 33 - Trang 265-272 - 2017
Takashi Yagi, Yoshihiro Fujikawa, Tomoko Sawai, Takeji Takamura-Enya, Sayoko Ito-Harashima, Masanobu Kawanishi
Aryl hydrocarbons such as 3-nitrobenzanthrone (NBA), 4-aminobiphenyl (ABP), acetylaminofluorene (AAF), benzo(a)pyrene (BaP), and 1-nitropyrene (NP) form bulky DNA adducts when absorbed by mammalian cells. These chemicals are metabolically activated to reactive forms in mammalian cells and preferentially get attached covalently to the N2 or C8 positions of guanine or the N6 position of adenine. The...... hiện toàn bộ
Antihyperglycemic and Antihyperlipidemic Effects of Fermented Rhynchosia nulubilis in Alloxan-induced Diabetic Rats
Toxicological Research - Tập 29 - Trang 15-19 - 2013
Min Jeong Kim, Bae Jin Ha
Alloxan administration in rats is used as a model for non-insulin dependent diabetes mellitus (NIDDM). NIDDM is a multifactorial disease, characterized by hyperglycemia and lipoprotein abnormalities. In this study, we evaluated the antihyperglycemic and antihyperlipidemic effects of fermented Rhynchosia nulubilis (FRN) through the regulation of glucose uptake in alloxan-induced rats. Fermented R. ...... hiện toàn bộ
Investigation of Water Safety in Non-treated Drinking Water with Trace Toxic Metals
Toxicological Research - Tập 29 - Trang 211-215 - 2013
Suw Young Ly, Dae Hong Kim, Ga Eun Lee
The trace toxic metal copper was assayed using mercury immobilized on a carbon nanotube electrode (MCW), with a graphite counter and a reference electrode. In this study, a macro-scale convection motor was interfaced with a MCW three-electrode system, in which a handmade MCW was optimized using cyclic- and square-wave stripping voltammetry. An analytical electrolyte for tap water was used instead ...... hiện toàn bộ
Erratum to: A Study on the Prevention of Salmonella Infection by Using the Aggregation Characteristics of Lactic Acid Bacteria
Toxicological Research - Tập 31 - Trang 219-219 - 2015
Min-Soo Kim, Yeo-Sang Yoon, Jae-Gu Seo, Hyun-Gi Lee, Myung-Jun Chung, Do-Young Yum
The authors regret that there is an error in the first sentence of the method section for ‘LAB and S. typhimurium preparation’. The correct text is shown below in bold.
Tổng số: 477   
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