An LC-MS/MS Method for Absolute Quantification of Nivolumab in Human Plasma: Application to Clinical Therapeutic Drug MonitoringTherapeutic Drug Monitoring - Tập 40 Số 6 - Trang 716-724 - 2018
Kei Irie, Akira Okada, Yuta Yamasaki, Chiyuki Kokan, Akito Hata, Reiko Kaji, Keizo Fukushima, Nobuyuki Sugioka, Yutaka Okada, Nobuyuki Katakami, Shoji Fukushima
Background: Nivolumab is a fully humanized IgG4 monoclonal antibody that targets
the programmed death-1 (PD-1) receptor, disrupting PD-1–mediated signaling and
restoring antitumor immunity. The objective of this study was to develop a
nivolumab quantification method using liquid chromatography-tandem mass
spectrometry (LC-MS/MS) and to evaluate its application in clinical therapeutic
drug monitori... hiện toàn bộ
Pharmacologic Treatment of Transplant Recipients Infected With SARS-CoV-2: Considerations Regarding Therapeutic Drug Monitoring and Drug–Drug InteractionsTherapeutic Drug Monitoring - Tập 42 Số 3 - Trang 360-368 - 2020
Laure Elens, Loralie J. Langman, Dennis A. Hesselink, Stein Bergan, Dirk Jan A. R. Moes, Mariadelfina Molinaro, Raman Venkataramanan, Florian Lemaître
Background: COVID-19 is a novel infectious disease caused by the severe acute
respiratory distress (SARS)-coronavirus-2 (SARS-CoV-2). Several therapeutic
options are currently emerging but none with universal consensus or proven
efficacy. Solid organ transplant recipients are perceived to be at increased
risk of severe COVID-19 because of their immunosuppressed conditions due to
chronic use of imm... hiện toàn bộ
Consensus Document: Therapeutic Monitoring of Tacrolimus (FK-506)Therapeutic Drug Monitoring - Tập 17 Số 6 - Trang 606-614 - 1995
William J. Jusko, Angus W. Thomson, John J. Fung, P McMaster, Steven Wong, E Zylber-Katz, Uwe Christians, M. Winkler, William E. Fitzsimmons, Ronald Lieberman, James H. McBride, Masakazu Kobayashi, V Warty, Steven J. Soldin
Pitfalls in Monitoring Tacrolimus (FK 506)Therapeutic Drug Monitoring - Tập 19 Số 6 - Trang 628-631 - 1997
Felix Braun, Ekkehard Schütz, Uwe Christians, T Lorf, J H Schiffmann, V W Armstrong, W. Schröter, Karl–Friedrich Sewing, Michael Oellerich, B. Ringe