Stroke
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Correlation between rCBF and histological changes following temporary middle cerebral artery occlusion.
Stroke - Tập 11 Số 5 - Trang 487-493 - 1980
Correlations between changes in regional, cortical, cerebral blood flow (rCBF)
and histological changes in the corresponding brain regions were examined
following middle cerebral arterial occlusion in 24 cats. In all animals, the
duration of arterial occlusion was 2 hours followed by 2 hours of recirculation.
The animals were divided into 2 groups according to the severity of the observed
histolog...
Regional cerebral blood flow in the anesthetized mouse as measured by local hydrogen clearance.
Stroke - Tập 8 Số 1 - Trang 103-106 - 1977
Platinum microelectrodes were used to measure H2 clearance in mouse brain, and
the clearance curves were used to calculate regional cerebral blood flow (rCBF).
The curves were usually biexponential, whether or not electrode placement was
confined to the cortex. When calculated by the height over area method, rCBF in
anesthetized mice averaged 37+/-14 and 49+/-15 ml/100 gm per minute in two
success...
The Hydrogen Clearance Method in Assessment of Blood Flow in Cortex, White Matter and Deep Nuclei of Baboons
Stroke - Tập 4 Số 4 - Trang 556-567 - 1973
The technique of hydrogen clearance by an inhalation method is discussed. The
electronic instrumentation necessary to secure stability and reproducibility
from the recordings is described. Clearance rates in gray matter of about 80
ml/100 gm per minute in the cortex and putamen have been obtained, and of about
20 ml/100 gm per minute in white matter.Clearance curves have invariably been
monoexpone...
Comparison between hydrogen clearance and microsphere technique for rCBF measurement.
Stroke - Tập 12 Số 2 - Trang 161-167 - 1981
Regional cerebral blood flow was measured repeatedly in anesthetized and
immobilized cats under various experimental conditions by recording the
clearance of inhaled hydrogen with inserted platinum electrodes and by recording
the distribution of 15 mu microspheres labeled with 3 different radioisotopes.
The values for both methods in normal cortical tissue were comparable (75.7 +/-
23.5 ml/100 g m...
A New Endoluminal, Flow-Disrupting Device for Treatment of Saccular Aneurysms
Stroke - Tập 38 Số 8 - Trang 2346-2352 - 2007
Background and Purpose— We report a preclinical study of a new endoluminal
device for aneurysm occlusion to test the hypothesis that the device, even
without use of intrasaccular coil placement, could occlude saccular aneurysms
without causing substantial parent artery compromise or compromise of adjacent,
small branch arteries. Methods— The Pipeline Neuroendovascular Device (Pipeline
NED; Chestnu...
Acute Cerebrovascular Events in Hospitalized COVID-19 Patients
Stroke - Tập 51 Số 9 - 2020
Background and Purpose: Initial reports suggest a significant risk of thrombotic
events, including stroke, in patients hospitalized with coronavirus disease 2019
(COVID-19). However, there is little systematic data on stroke incidence and
mechanisms, particularly in racially diverse populations in the United States.
Methods: We performed a retrospective, observational study of stroke incidence
and...
Cortical Neurogenesis in Adult Rats After Transient Middle Cerebral Artery Occlusion
Stroke - Tập 32 Số 5 - Trang 1201-1207 - 2001
Background and Purpose —This study explored the possible occurrence of newly
generated nerve cells in the ischemic cortex of adult rats after middle cerebral
artery occlusion and reperfusion. Methods —Nine- to 10-week-old male Wistar rats
were subjected to 2 hours of middle cerebral artery occlusion by the
monofilament method. Rats received repeated intraperitoneal injections of the
cell prolifera...
Artificial Embolization of the Middle Cerebral Artery in Primates
Stroke - Tập 6 Số 4 - Trang 387-390 - 1975
Artificial embolization of the middle cerebral artery (MCA) was produced in the
primate, with a technique similar to that described by Luessenhop and Spence
(1960) for the treatment of an inoperable arteriovenous malformation in the
territory of the MCA. Silicone spheres (1 to 1.5 mm in diameter) were introduced
into the internal carotid artery (ICA) via the external carotid artery (ECA).
Emboli (...
Dementia associated with lacunar infarction.
Stroke - Tập 23 Số 9 - Trang 1225-1229 - 1992
The purpose of this study was to assess the number of patients with lacunar
lesions who develop dementia and to evaluate in patients with and without
dementia the relevance of risk factors for cerebrovascular disease, the
occurrence of leukoaraiosis, the volume and location of vascular lesions, the
size of ventricular and subarachnoid spaces, and stroke recurrence. One hundred
eight patients in wh...
Measurement variability in duplex scan assessment of carotid atherosclerosis.
Stroke - Tập 23 Số 2 - Trang 215-220 - 1992
The reproducibility of duplex scan measures of carotid atherosclerosis was
evaluated as part of a study assessing the prevalence of carotid disease in
elderly adults. Doppler measures of blood flow velocity were used to evaluate
disease severity, and extent of carotid plaque was scored from the B-mode image.
A reader assigned a grade from 0 to 3 to each of seven segments in the carotid
system, bas...
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