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Identification of Key Gene Targets for Sensitizing Colorectal Cancer to Chemoradiation: an Integrative Network Analysis on Multiple Transcriptomics Data
Springer Science and Business Media LLC - Tập 53 - Trang 649-668 - 2021
Hamed Manoochehri, Akram Jalali, Hamid Tanzadehpanah, Amir Taherkhani, Massoud Saidijam
Colorectal cancer (CRC) is a main cause of morbidity and mortality in the world. Chemoradioresistance is a major problem in CRC treatment. Identification of novel therapeutic targets in order to overcome treatment resistance in CRC is necessary. In this study, gene expression omnibus (GEO) database was searched to find microarray datasets. Data normalization/analyzing was performed using ExAtlas. ...... hiện toàn bộ
Carbamazepine, một chất ức chế histone deacetylase gây ra hiện tượng apoptosis ở dòng tế bào adenocarcinoma đại trực tràng người HT-29 Dịch bởi AI
Springer Science and Business Media LLC - Tập 51 - Trang 564-570 - 2019
Sohaib M, Ezhilarasan D
Ung thư đại trực tràng đứng thứ tư và gây ra 10% tỷ lệ tử vong liên quan đến ung thư ở các nước phương Tây. Tỷ lệ mắc bệnh đang gia tăng ở nhiều quốc gia do việc áp dụng rộng rãi chế độ ăn uống và lối sống phương Tây. Carbamazepine (CBZ) là một loại thuốc chống động kinh được FDA phê duyệt và là một chất ức chế histone deacetylase. Mục tiêu của nghiên cứu này là đánh giá khả năng gây độc tế bào củ...... hiện toàn bộ
#Carbamazepine #Apoptosis #Histone Deacetylase Inhibitor #Colon Cancer #HT-29 Cells
Bevacizumab in Combination with Chemotherapy for Colorectal Brain Metastasis
Springer Science and Business Media LLC - Tập 47 Số 1 - Trang 82-88 - 2016
Fabian Finkelmeier, Se‐Jong You, Oliver Waidmann, Robert A. Wolff, Stefan Zeuzem, Oliver Bähr, Jörg Trojan
MALT Lymphoma of the Gastric Remnant After Roux-en-Y Gastric Bypass
Springer Science and Business Media LLC - Tập 43 - Trang 194-197 - 2012
Ahmed Jawad, Allan H. Bar, Demetri Merianos, Jing Zhou
A Meta-analysis of Total Neoadjuvant Therapies Combining Chemoradiotherapy with Induction or Consolidated Chemotherapy for Locally Advanced Rectal Cancer
Springer Science and Business Media LLC - Tập 54 - Trang 693-702 - 2022
Pengkhun Nov, Kunpeng Du, Zijian Huang, Yanyang Li, Min Gong, Xiang Liu, Chunhui Li, Lilin Li, Duanyu Wang, Yangfeng Zhang, Changqian Wang, Jiqiang Li
Total neoadjuvant therapy (TNT) combining chemoradiotherapy (CRT) with chemotherapy (CT) was a novel pre-surgical approach to cancer treatment. This meta-analysis aimed to compare the clinical outcomes between neoadjuvant CRT (nCRT) with induction CT and nCRT with consolidated CT in locally advanced rectal cancer (LARC) patients. In July 2022, a literature search was conducted using the following ...... hiện toàn bộ
Isolated Portal Venous Hepatocellular Carcinoma
Springer Science and Business Media LLC - Tập 48 - Trang 80-82 - 2016
John Mutai, Twahirwa Nebayosi, Joyce Sande, M. V. Shah
Rare, Unusual Causality of Acute Appendicitis
Springer Science and Business Media LLC - Tập 52 - Trang 759-765 - 2020
Katleen K. Janssens, Dorien Mannens, Sabine Declercq, Menno Maes, Steven M. Van Outryve
Cystic Neuroendocrine Tumor of Retroperitoneum Origin—a Case Report
Springer Science and Business Media LLC - - 2016
Heejin Kwon
Adenocarcinoma of the Gastro-jejunal Anastomosis After One Anastomosis Gastric Bypass
Springer Science and Business Media LLC - - Trang 1-3 - 2023
Christian Mouawad, Houssam Dahboul, Daniel Kazan, Bilal Chamaa, Michael Osseis, Roger Noun, Ghassan Chakhtoura
One anastomosis gastric bypass (OAGB) is mainly criticized for the supposed carcinogenic effect of bile reflux on the gastric pouch mucosa. A 56-year-old male patient presented 12 years after OAGB with a 10-month history of gradual dysphagia and vomiting. He was diagnosed with a tumor of the gastro-jejunal anastomosis, and underwent total gastrectomy with D2 lymphadenectomy. Specimen examination s...... hiện toàn bộ
Incidence of Brain Metastasis as First Event in Patients with Esophageal Carcinoma: a Report from Three Prospective Alliance Clinical Trials
Springer Science and Business Media LLC - Tập 54 - Trang 846-854 - 2022
Ron S. Smith, Nathan R. Foster, Aminah Jatoi, Stephan D. Thomé, Robert C. Miller
Historically, reported incidence of brain metastasis secondary to esophageal carcinoma is low. We sought to determine the incidence of brain metastasis in a contemporary cohort of patients with carcinoma of the esophagus. Data from patients with localized esophageal carcinoma prospectively enrolled on three curative intent Alliance treatment trials (N0044, N0342, N044E) were reviewed including tim...... hiện toàn bộ
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