Genotoxicity of Psychotropic Drugs in Experimental and Clinical StudiesSpringer Science and Business Media LLC - Tập 53 - Trang 776-785 - 2023
A. D. Durnev, N. V. Eremina, A. K. Zhanataev, L. G. Kolik
Data from studies of the genotoxic activity of psychotropic drugs published over the past 25 years were analyzed. Information describing the genotoxicity of psychotropic drugs was found to be fragmentary and inconsistent, and the experimental conditions in which they were produced often fail to meet accepted requirements. Among the 94 drugs considered, sufficient data for concluding that genotoxic...... hiện toàn bộ
Modulation by Nitric Oxide (NO) of the Intensity of Non-Quantum Mediator Secretion in Neuromuscular Junctions in RatsSpringer Science and Business Media LLC - Tập 31 - Trang 451-455 - 2001
M. R. Mukhtarov, A. Kh. Urazaev, E. E. Nikol'skii, F. Vyskocil
Experiments on rat diaphragm muscle showed that the nitric oxide (NO) donors sodium nitroprusside (SNP) and S-nitroso-N-acetylpenicillamine (SNAP), as well as L-arginine, a substrate for NO synthesis, decreased the level of muscle fiber hyperpolarization (the H effect) after blockade of cholinoceptors on the postsynaptic membrane by d-tubocurarine in conditions of irreversible inhibition of acetyl...... hiện toàn bộ