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Phosphorylase isoenzymes of human brain
Springer Science and Business Media LLC - Tập 1 - Trang 171-178 - 1983
Nereo Bresolin, Armand F. Miranda, Mercedes P. Jacobson, Jeen Hyung Lee, Thomas Capilupi, Salvatore Dimauro
The isoenzyme pattern of phosphorylase in human brain was studied by polyacrylamide slab gel electrophoresis and activity was revealed by iodine stain and by autoradiography: A major fast-migrating band was similar to isoenzyme I of the heart; an intermediate band migrated like the hybrid cardiac isoenzyme II; and a slow-migrating band, best revealed by autoradiography, migrated like the “muscle” ... hiện toàn bộ
The role of astrocytes in hepatic encephalopathy
Springer Science and Business Media LLC - Tập 6 - Trang 13-33 - 1987
Michael D. Norenberg
The Alzheimer type II astrocyte change is the distinctive morphologic alteration in brain of humans and experimental animals succumbing to hepatic encephalopathy (HE). Whether this change is a primary event in the pathogenesis of HE or whether it is secondary to injury of some other component(s) of the CNS has not been clarified. Studies in a rat model of HE have revealed early reactive changes in... hiện toàn bộ
Genetic galactosylceramidase deficiency (Globoid cell leukodystrophy, Krabbe disease) in different mammalian species
Springer Science and Business Media LLC - Tập 3 - Trang 53-68 - 1983
Kunihiko Suzuki, Kinuko Suzuki
Globoid cell leukodystrophy (Krabbe disease) in man is a rare genetic disorder caused by deficiency of galactosylceramidase activity. Clinical and pathological manifestations are almost exclusively confined to the nervous system, particularly to the white matter and the peripheral nerve. The disease also occurs in four other mammalian species: dog, cat, sheep and mouse. Except for the feline disea... hiện toàn bộ
Dorsal root axonal regeneration in the adult frog spinal cord
Springer Science and Business Media LLC - Tập 5 - Trang 237-253 - 1986
Francis J. Liuzzi, Raymond J. Lasek
The frog dorsal root provides a useful model for the study of axonal regeneration in an adult vertebrate CNS. We have used the model to compare the regeneration of two very different types of axons within the same CNS environment and have found that regenerating dorsal root, as well as rerouted motoneuron axons, display similar growth patterns in the spinal cord. Both sensory and motor axons grow ... hiện toàn bộ
Sudanophilic leukodystrophy with large amounts of cholesterol ester
Springer Science and Business Media LLC - Tập 1 - Trang 103-123 - 1983
Allan J. Yates, Yasuo Kishimoto, Charles Richard, Karen L. Shoup
The patient was a 31-yr-old white male who developed behavioral abnormalities 6 months prior to death. He became progressively lethargic, socially withdrawn and somnolent. Over the 2 months prior to death his memory worsened, he exhibited an increasingly stumbling gait, and he developed multiple cranial nerve deficits. he became comatose, developed respiratory insufficiency, and died. The brain ha... hiện toàn bộ
Ammonia: Key factor in the pathogenesis of hepatic encephalopathy
Springer Science and Business Media LLC - Tập 6 - Trang 1-12 - 1987
Roger F. Butterworth, Jean-François Giguère, Jean Michaud, Joël Lavoie, Gilles Pomier Layrargues
There is substantial clinical and experimental evidence to suggest that ammonia toxicity is a major factor in the pathogenesis of hepatic encephalopathy associated with subacute and chronic liver disease. Ammonia levels in patients with severe liver disease are frequently found to be elevated both in blood and cerebrospinal fluid (csf). Hepatic encephalopathy results in neuropathological damage of... hiện toàn bộ
Announcements
Springer Science and Business Media LLC - Tập 5 - Trang 85-86 - 1986
Biochemical aspects of globoid and metachromatic leukodystrophies
Springer Science and Business Media LLC - Tập 2 Số 3 - Trang 189-218 - 1984
Akhlaq A. Farooqui, Lloyd A. Horrocks
Rabbit brain lipids during short-term hyperthermia
Springer Science and Business Media LLC - Tập 4 - Trang 153-163 - 1986
K. Domańska-Janik, Z. Dąbrowiecki, W. Gordon-Majszak, J. Strosznajder
Rabbits were subjected to 3 h of hyperthermia at 40°C. The phospholipid content of the brain was unchanged, whereas the free fatty acids increased by about 73% over control levels. Hyperthermia also induced inhibition of fatty acid peroxidation processes. The last products of fatty acid peroxidation, the thiobarbituric acid reactive substances, diminished significantly during hyperthermia, whereas... hiện toàn bộ
The multimolecular cascade of spinal cord injury
Springer Science and Business Media LLC - Tập 7 - Trang 57-77 - 1987
Naren L. Banik, Edward L. Hogan, Chung Y. Hsu
Experimental spinal cord injury in animals induced by weight drop produces neurological deficit and paralysis. Correlation of the progressive morphological changes in the lesion by both light and electron microscopy with the biochemical alterations revealed ischemia, edema, hemorrhage, tissue necrosis, granular changes in axons, vesicular degeneration of myelin and axonal calcification. The bioche... hiện toàn bộ
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