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Clinical and histological risk factors for progression of IgA nephropathy: an update in children, young and adult patients
Springer Science and Business Media LLC - Tập 30 - Trang 339-346 - 2016
Rosanna Coppo
The identification of risk factors conditioning the progression of immunoglobulin (Ig)A nephropathy (IgAN) is needed due to the variability of the outcome of this renal disease, which ranges from remission or indolent course to progressive slow loss of renal function or rapidly evolving chronic renal failure. Based on the supposed individual risk of progression, the therapy is modulated from renin...... hiện toàn bộ
Glomerular injury after trauma, burn, and sepsis
Springer Science and Business Media LLC - Tập 36 - Trang 2417-2429 - 2023
Lorena Schult, Rebecca Halbgebauer, Ebru Karasu, Markus Huber-Lang
Acute kidney injury development after trauma, burn, or sepsis occurs frequently but remains a scientific and clinical challenge. Whereas the pathophysiological focus has mainly been on hemodynamics and the downstream renal tubular system, little is known about alterations upstream within the glomerulus post trauma or during sepsis. Particularly for the glomerular endothelial cells, mesangial cells...... hiện toàn bộ
Prevalence of hyperuricemia among Chinese adults: a national cross-sectional survey using multistage, stratified sampling
Springer Science and Business Media LLC - Tập 27 Số 6 - Trang 653-658 - 2014
Liu, Hong, Zhang, Xiao-Min, Wang, Yan-Li, Liu, Bi-Cheng
Hyperuricemia is a non-communicable disease that threatens human health, and its prevalence has been increasing in recent decades. However, there have been no national surveys about hyperuricemia performed in China. We aimed to investigate the prevalence of hyperuricemia and its risk factors in Chinese adults. Using data from 36,348 participants aged 18 years and older from the China National...... hiện toàn bộ
Temporal trends in prevalence and disability of chronic kidney disease caused by specific etiologies: an analysis of the Global Burden of Disease Study 2019
Springer Science and Business Media LLC - - 2024
Xin Qing, Junyi Jiang, Chunlei Yuan, Kunke Xie, Ke Wang
The prevalence of disability in CKD is high. In this context the aim of the present study was to assess the  temporal trends of prevalence and disability progression for chronic kidney disease (CKD) caused by specific etiologies. Using data from the Global Burden of Diseases Study (GBD) 2019, we examined the age-standardized rates of CKD prevalence and disability-adjusted life-years for different ...... hiện toàn bộ
Is withdrawal of nocturnal hyperhydration possible in children with primary hyperoxaluria treated with RNAi?
Springer Science and Business Media LLC - Tập 36 - Trang 1473-1476 - 2023
Nathalie Biebuyck, Camille Destombes, Richa Prakash, Olivia Boyer
Primary hyperoxaluria type 1 is a rare genetic disorder caused by bi-allelic pathogenic variants in the AGXT gene leading to an overproduction of oxalate which accumulates in the kidneys in the form of calcium oxalate crystals. Thus, patients may present with recurrent nephrocalcinosis and lithiasis, with progressive impairment of the  renal function and eventually kidney failure.  There is no spe...... hiện toàn bộ
Atheroembolic renal disease associated with dabigatran overdose
Springer Science and Business Media LLC - Tập 35 - Trang 1053-1057 - 2021
Maria Chiara Pacchiarini, Giuseppe Vizzini, Chiara Italiano, Enrico Fiaccadori, Giovanni Maria Rossi
Assessing accuracy of estimated dry weight in dialysis patients post transplantation: the kidney knows best
Springer Science and Business Media LLC - Tập 34 - Trang 2093-2097 - 2021
Michael J Germain, Barbara A Greco, Spencer Hodgins, Bikash Chapagain, Ravi Thadhani, David Wojciechowski, Kerry Crisalli, Brian H. Nathanson, Yossi Chait
Estimated dry weight is used to guide fluid removal during outpatient hemodialysis sessions. Errors in estimated dry weight can result in intradialytic hypotension and interdialytic fluid overload. The goal of this study was to assess the accuracy of estimated dry weight by comparing it to the 2-week post-transplant weight in two cohorts of hemodialysis patients. This observational, multi-cente...... hiện toàn bộ
Lower magnesium level associated with new-onset diabetes and pre-diabetes after kidney transplantation
Springer Science and Business Media LLC - Tập 27 - Trang 339-344 - 2014
Neetika Garg, Janice Weinberg, Sandeep Ghai, Gitana Bradauskaite, Matthew Nuhn, Amitabh Gautam, Nilay Kumar, Jean Francis, Joline L. T. Chen
Hypomagnesemia is associated with increased peripheral insulin resistance in the general population. It is frequently seen after renal transplantation. We examined its role as a risk factor for new-onset diabetes after transplantation (NODAT) and new-onset pre-diabetes after transplantation (NOPDAT). A retrospective analysis of 138 previously non-diabetic renal transplant recipients was conducted....... hiện toàn bộ
Transcription factor NRF2 as potential therapeutic target for preventing muscle wasting in aging chronic kidney disease patients
Springer Science and Business Media LLC - Tập 35 - Trang 2215-2225 - 2022
Erika F. Gómez-García, Fabiola Martín del Campo, Laura Cortés-Sanabria, Francisco Mendoza-Carrera, Carla Maria Avesani, Peter Stenvinkel, Bengt Lindholm, Alfonso M. Cueto-Manzano
Increased muscle protein catabolism leading to muscle wasting is a prominent feature of the syndrome of protein-energy wasting (PEW) in patients with chronic kidney disease (CKD). PEW and muscle wasting are induced by factors such as inflammation, oxidative stress and metabolic acidosis that activate the ubiquitin–proteasome system, the main regulatory mechanism of skeletal muscle degradation. Whe...... hiện toàn bộ
Nephrology a discipline evolving into complexity: between complex systems and philosophy
Springer Science and Business Media LLC - Tập 33 - Trang 1-4 - 2019
Natale G. De Santo
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