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Reply to the letter by Gaetano Loscocco, Secondary hemophagocytic lymphohistiocytosis, HScore and COVID-19
Springer Science and Business Media LLC - Tập 112 Số 1 - Trang 127-127 - 2020
Akiyoshi Takami
Acute lower limb ischemia in a patient with aortic thrombus and essential thrombocytosis
Springer Science and Business Media LLC - Tập 90 - Trang 343-346 - 2009
P. Caridad Morata Barrado, E. Blanco Cañibano, B. García Fresnillo, M. Guerra Requena
Aortic thrombus is rare in patients with essential thrombocytosis (ET), so the optimal treatment remains undefined. A 45-year-old man with history of ET, under chronic treatment with aspirin, presented to the emergency department complaining of acute onset in both the legs and abdominal pain. Physical examination revealed that both dorsalis pedis pulses were not palpable with cold and pale feet. H...... hiện toàn bộ
High serum ferritin levels in newly diagnosed patients with myelodysplastic syndromes are associated with greater symptom severity
Springer Science and Business Media LLC - - 2020
Giovanni Caocci, Marco Vignetti, Andrea Patriarca, Massimo Breccia, Uwe Platzbecker, Giuseppe A. Palumbo, Reinhard Stauder, Francesco Cottone, Duska Petranovic, Maria Teresa Voso, Agostino Tafuri, Rosangela Invernizzi, Jo Caers, Mario Luppi, Giorgio La Nasa, Pasquale Niscola, Fabio Efficace
We examined the association between serum ferritin (SF) levels and patient-reported functional aspects and symptoms, as measured by the EORTC QLQ-C30, in newly diagnosed patients with myelodysplastic syndromes (MDS). Analysis was conducted on 497 MDS patients who were classified in two groups based on the SF value of 1000 ng/mL. Clinically relevant differences of patient-reported functional and sy...... hiện toàn bộ
Regulation of Hematopoietic Stem Cell Processing and Transplantation
Springer Science and Business Media LLC - Tập 75 - Trang 237-245 - 2002
Scott D. Rowley
The widespread use of tissue including hematopoietic stem cell products is justification for the development of standards by professional societies and for regulation by governmental agencies. The Food and Drug Administration (FDA) developed a tiered, risk-based regulatory model.At the low end of risk to the tissue recipient, the regulations being developed by the FDA are comparable to standards d...... hiện toàn bộ
AbnormalN-Glycosylation of the Immunoglobulin G κ Chain in a Multiple Myeloma Patient with Crystalglobulinemia: Case Report
Springer Science and Business Media LLC - Tập 85 - Trang 203-206 - 2007
Ryo Hashimoto, Tosifusa Toda, Hisashi Tsutsumi, Masatsugu Ohta, Mayumi Mori
Spontaneous crystallization of monoclonal immunoglobulins (crystalglobulin) is a rare complication of multiple myeloma. We describe a 64-year-old Japanese man with skin ulcers and renal failure associated with immunoglobulin G κ multiple myeloma. Crystallized immunoglobulin was detected in his serum at room temperature. Analysis of the patient’s crystalglobulin by sodium dodecyl sulfate-polyacryla...... hiện toàn bộ
Quantification of bone-marrow plasma cell levels using various International Myeloma Working Group response criteria in patients with multiple myeloma
Springer Science and Business Media LLC - Tập 108 - Trang 371-374 - 2018
Kentaro Narita, Hiroki Kobayashi, Yoshiaki Abe, Hiroaki Kitadate, Masami Takeuchi, Kosei Matsue
We examined the association of residual bone-marrow plasma cells (PCs) and International Myeloma Working Group (IMWG) response assessment in light-chain-only multiple myeloma (LCMM) and intact immunoglobulin multiple myeloma (IIMM) using multicolour flow cytometry (MFC). We identify considerable differences in bone-marrow neoplastic PC levels between IIMM and LCMM for the same IMWG response catego...... hiện toàn bộ
Predictive and risk factor analysis for bloodstream infection in high-risk hematological patients with febrile neutropenia: post-hoc analysis from a prospective, large-scale clinical study
Springer Science and Business Media LLC - Tập 114 - Trang 472-482 - 2021
Akinao Okamoto, Yoshinobu Kanda, Shun-ichi Kimura, Tatsuo Oyake, Kazuo Tamura
Bloodstream infection (BSI) is a frequent complication observed in patients with febrile neutropenia (FN). BSI risk factors and incidence vary depending on chemotherapy types and prophylactic antimicrobial agents. We clarified these issues by post-hoc analysis of a prospective clinical trial cohort for severe FN in hematological malignancy. We performed an intention-to-treat analysis of 413 high-r...... hiện toàn bộ
Recombinant Factor VIIa is an Effective Therapy for Abdominal Surgery and Severe Thrombocytopenia: A Case Report
Springer Science and Business Media LLC - Tập 81 - Trang 75-76 - 2005
Venancio Conesa, Andrés Navarro-Ruiz, Joaquín Borrás-Blasco, Angela Mompel, Amparo GÓmez, Mercedes González
A 50-year-old woman was admitted to the emergency room. An appendectomy was done. On the sixth day the patient’s general state deteriorated and she became somnolent with jaundice due to distal obstructive choledocholithiasis. The results of laboratory tests were platelets 12 x 109/L, prothrombin time 13 seconds, international normalized ratio 1.19, activated partial thromboplastin time 31.8 second...... hiện toàn bộ
A case of Klinefelter syndrome with aplastic anemia
Springer Science and Business Media LLC - Tập 93 - Trang 213-215 - 2011
Chao Xu, Cai-Yu Zhang, Nan Chen, Xun Sun, Ye Xiao, Ling Gao, Jia-Jun Zhao
In this manuscript, we report the first patient who suffered from Klinefelter syndrome with aplastic anemia and hyperprolactinemia.
Antibody therapy for Adult T-cell leukemia–lymphoma
Springer Science and Business Media LLC - - 2011
Takashi Ishida, Ryuzo Ueda
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