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Reply to the letter by Gaetano Loscocco, Secondary hemophagocytic lymphohistiocytosis, HScore and COVID-19
Springer Science and Business Media LLC - Tập 112 Số 1 - Trang 127-127 - 2020
Akiyoshi Takami
Regulation of Hematopoietic Stem Cell Processing and Transplantation
Springer Science and Business Media LLC - Tập 75 - Trang 237-245 - 2002
Scott D. Rowley
The widespread use of tissue including hematopoietic stem cell products is justification for the development of standards by professional societies and for regulation by governmental agencies. The Food and Drug Administration (FDA) developed a tiered, risk-based regulatory model.At the low end of risk to the tissue recipient, the regulations being developed by the FDA are comparable to standards d...... hiện toàn bộ
AbnormalN-Glycosylation of the Immunoglobulin G κ Chain in a Multiple Myeloma Patient with Crystalglobulinemia: Case Report
Springer Science and Business Media LLC - Tập 85 - Trang 203-206 - 2007
Ryo Hashimoto, Tosifusa Toda, Hisashi Tsutsumi, Masatsugu Ohta, Mayumi Mori
Spontaneous crystallization of monoclonal immunoglobulins (crystalglobulin) is a rare complication of multiple myeloma. We describe a 64-year-old Japanese man with skin ulcers and renal failure associated with immunoglobulin G κ multiple myeloma. Crystallized immunoglobulin was detected in his serum at room temperature. Analysis of the patient’s crystalglobulin by sodium dodecyl sulfate-polyacryla...... hiện toàn bộ
Recombinant Factor VIIa is an Effective Therapy for Abdominal Surgery and Severe Thrombocytopenia: A Case Report
Springer Science and Business Media LLC - Tập 81 - Trang 75-76 - 2005
Venancio Conesa, Andrés Navarro-Ruiz, Joaquín Borrás-Blasco, Angela Mompel, Amparo GÓmez, Mercedes González
A 50-year-old woman was admitted to the emergency room. An appendectomy was done. On the sixth day the patient’s general state deteriorated and she became somnolent with jaundice due to distal obstructive choledocholithiasis. The results of laboratory tests were platelets 12 x 109/L, prothrombin time 13 seconds, international normalized ratio 1.19, activated partial thromboplastin time 31.8 second...... hiện toàn bộ
A case of Klinefelter syndrome with aplastic anemia
Springer Science and Business Media LLC - Tập 93 - Trang 213-215 - 2011
Chao Xu, Cai-Yu Zhang, Nan Chen, Xun Sun, Ye Xiao, Ling Gao, Jia-Jun Zhao
In this manuscript, we report the first patient who suffered from Klinefelter syndrome with aplastic anemia and hyperprolactinemia.
Antibody therapy for Adult T-cell leukemia–lymphoma
Springer Science and Business Media LLC - - 2011
Takashi Ishida, Ryuzo Ueda
Association of high levels of plasma OX40 with acute adult T-cell leukemia
Springer Science and Business Media LLC - Tập 109 - Trang 319-327 - 2019
Yuetsu Tanaka, Yoshiaki Takahashi, Reiko Tanaka, Takuya Miyagi, Mineki Saito, Takuya Fukushima
OX40, a member of the tumor necrosis factor receptor (TNFR) superfamily, co-stimulates activated T cells following interaction with its own ligand OX40L. Human T-cell leukemia virus type-1 (HTLV-1) is an etiological agent of adult T-cell leukemia (ATL). ATL cells are known to express cell surface OX40; however, the level of soluble OX40 (sOX40) in blood samples from ATL patients is unknown. Quanti...... hiện toàn bộ
Gene transfer for hemophilia and viral infection
Springer Science and Business Media LLC - Tập 76 - Trang 147-147 - 2002
Mark A. Kay
The goal of our work has been to establish an experimental basis for gene transfer as a method of treating hemophilia, an inherited bleeding disorder that results from the absence of functional Factor VIII or Factor IX. We have carried out pre-clinical and clinical studies of AAV-mediated gene transfer of the Factor IX gene in animal models and in human subjects with severe hemophilia B. Target ti...... hiện toàn bộ
IL-6-positive classical Hodgkin’s lymphoma co-occurring with plasma cell type of Castleman’s disease: report of a case
Springer Science and Business Media LLC - Tập 97 - Trang 275-279 - 2013
Akihito Momoi, Masaru Kojima, Takeshi Sakai, Junya Ajiro, Noriatsu Isahai, Kouichi Nagai, Sadao Aoki
We present a case of classical Hodgkin’s lymphoma (HL) co-occurring with histological features of Castleman’s disease (CD). A 25-year-old man presented with left supraclavicular and axillary lymph node swelling and mediastinal mass. Using an initial biopsy specimen from left axillary lymph node, a tentative diagnosis of multicentric CD of plasma cell type was made. The serum level of interleukin-6...... hiện toàn bộ
Dendritic Cells and Immunotherapy for Cancer
Springer Science and Business Media LLC - Tập 77 - Trang 439-443 - 2003
David H. Chang, Madhav V. Dhodapkar
Dendritic cells, nature’s adjuvant, are antigen-presenting cells specialized to initiate and regulate immunity. Their potent antigen-presenting function has encouraged targeting of dendritic cells (DCs) for harnessing the immune system against cancer. DCs are efficient at activating not only CD4+ helper T-cells and CD8+ killer T-cells but also B-cells and innate effectors such as natural killer an...... hiện toàn bộ
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