In vivo imaging of oxidative stress and fronto-limbic white matter integrity in young adults with mood disordersSpringer Science and Business Media LLC - Tập 268 - Trang 145-156 - 2017
Daniel F. Hermens, Sean N. Hatton, Rico S. C. Lee, Sharon L. Naismith, Shantel L. Duffy, G. Paul Amminger, Manreena Kaur, Elizabeth M. Scott, Jim Lagopoulos, Ian B. Hickie
Fronto-limbic connectivity is compromised in mood disorders, as reflected by impairments in white matter (WM) integrity revealed by diffusion tensor imaging. Although the underlying mechanisms remain unclear, disruption to normal myelination due to oxidative stress is thought to play a key role. We aimed to determine whether fronto-limbic WM integrity is compromised, and associated with in vivo an...... hiện toàn bộ
Der Einfluß frühkindlicher Hirnschäden auf Art und Verlauf psychischer Erkrankungen bei ErwachsenenSpringer Science and Business Media LLC - Tập 220 - Trang 361-371 - 1975
H. P. Vogel
Die Daten von 1926 stationär behandelten, psychiatrischen Patienten der Jahre 1968–1972, welche mit dem AMP-Dokumentationssystem erfaßt worden waren, wurden hinsichtlich der Häufigkeit des anamnestischen Merkmals „Frühkindlicher Hirnschaden“ ausgewertet. Es fanden sich 82 Merkmalsträger (4,26%). Zu jedem Patienten mit frühkindlichem Hirnschaden wurde ein Kontrollfall gleichen Alters, Geschlechts u...... hiện toàn bộ
Do antipsychotics lead to cognitive impairment in dementia? A meta-analysis of randomised placebo-controlled trialsSpringer Science and Business Media LLC - Tập 267 - Trang 187-198 - 2016
Alexander Wolf, Stefan Leucht, Frank-Gerald Pajonk
Behavioural and psychological symptoms in dementia (BPSD) are common and often treated with antipsychotics, which are known to have small efficacy and to cause many side effects. One potential side effect might be cognitive decline. We searched MEDLINE, Scopus, CENTRAL and
www.ClincalStudyResult.org
for randomized, double-blind, placebo-contro...... hiện toàn bộ