Detection of inflammatory cytokines in psoriatic skinSpringer Science and Business Media LLC - Tập 287 - Trang 158-164 - 1995
Yoko Yoshinaga, Meguma Higaki, Satomi Terajima, Emiko Ohkubo, Toshitatsu Nogita, Nobuyuki Miyasaka, Makota Kawashima
Recent investigations have revealed the involvement of cytokines in the pathogenesis of psoriasis. This study examined the amount of inflammatory cytokines — interleukin-1 (IL-1), interleukin-6 (IL-6) and granulocyte macrophage colony-stimulating factor (GM-CSF) — released into the supernatants of organ cultures of involved and uninvolved skin from psoriatic patients and normal skin from healthy i...... hiện toàn bộ
Complete prevention of radiation-induced dermatitis using topical adrenergic vasoconstrictorsSpringer Science and Business Media LLC - Tập 308 Số 10 - Trang 751-757 - 2016
Fahl, William E.
Radiation dermatitis is a commonly occurring, painful, side effect of cancer radiotherapy that causes some patients to withdraw from the radiotherapy course. Our goal was to test and optimize topical application of an adrenergic vasoconstrictor to rat skin in a preclinical test to prevent radiation-induced dermatitis. A radiation dermatitis assay was developed in which 17.2 Gy to a 1.5 ×...... hiện toàn bộ
Prognostic significance in malignant melanoma of nuclear DNA content measured by a microfluorimetric methodSpringer Science and Business Media LLC - Tập 287 - Trang 718-722 - 1995
Yoshihiro Umebayashi, Fujio Otsuka
The nuclear DNA content of 47 primary malignant melanomas was measured by 4′,6-diamidino-2-phenylindole-DNA (DAPI-DNA) microfluorimetry, and the DNA index, a quantitative measure of nuclear DNA content, was calculated. The DNA index and other clinical and pathological variables were examined and compared with patient survival using univariate and multivariate analyses. The Kaplan-Meier life table ...... hiện toàn bộ