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Effect of tissue engineering small vessel scaffolds in experimental animals
Springer Science and Business Media LLC - Tập 9 - Trang 109-115 - 2012
Huayong Chen, Shuling Bai, Yingqing Chen
Acellular xenogeneic small vessel scaffolds preliminarily eliminate the xenogeneic antigen that could induce an immune rejection. We transplanted the Wistar rat caudal artery scaffolds into Japanese white rabbit ear central arteries, and observed the changes of blood flow and vessel wall. We acquired 30 caudal arteries from 15 Wistar rats, some were directly assigned as caudal artery group, the ot...... hiện toàn bộ
A Non-woven Path: Electrospun Poly(lactic acid) Scaffolds for Kidney Tissue Engineering
Springer Science and Business Media LLC - Tập 15 Số 3 - Trang 301-310 - 2018
Todd P Burton, Anthony Callanan
Heparin/Collagen 3D Scaffold Accelerates Hepatocyte Differentiation of Wharton’s Jelly-Derived Mesenchymal Stem Cells
Springer Science and Business Media LLC - Tập 14 - Trang 443-452 - 2017
Fatemeh Aleahmad, Sepideh Ebrahimi, Mahin Salmannezhad, Mahnaz Azarnia, Mansooreh Jaberipour, Mojtaba Hoseini, Tahereh Talaei-Khozani
Both mature and stem cell-derived hepatocytes lost their phenotype and functionality under conventional culture conditions. However, the 3D scaffolds containing the main extracellular matrix constitutions, such as heparin, may provide appropriate microenvironment for hepatocytes to be functional. The current study aimed to investigate the efficacy of the differentiation capability of hepatocytes d...... hiện toàn bộ
Intravitreal delivery of mesenchymal stem cells loaded onto hydrogel affects the regulatory expression of endogenous NGF and BDNF in ischemic rat retina
Springer Science and Business Media LLC - Tập 9 - Trang 249-258 - 2012
Ji-Yeon Lee, Ji-Man Shin, Chung Eun Yeum, Gue Tae Chae, Myung-Hoon Chun, Su-Ja Oh
The utility of a biodegradable hyaluronic acid (HyA)-based hydrogel as a tissue scaffold for intravitreal carriage of mesenchymal stem cells (MSCs) into the retina was tested. A rat model of retinal ischemia-reperfusion (IR) injury was used. DiI-labeled MSCs from three passages were loaded onto hydrogel and injected into the vitreous body of experimental and control eyeballs 1 week after IR. The n...... hiện toàn bộ
Retinal Tissue Bioengineering, Materials and Methods for the Treatment of Glaucoma
Springer Science and Business Media LLC - Tập 17 - Trang 253-269 - 2020
Sanaz Behtaj, Andreas Öchsner, Yuri G. Anissimov, Maksym Rybachuk
Glaucoma, a characteristic type of optic nerve degeneration in the posterior pole of the eye, is a common cause of irreversible vision loss and the second leading cause of blindness worldwide. As an optic neuropathy, glaucoma is identified by increasing degeneration of retinal ganglion cells (RGCs), with consequential vision loss. Current treatments only postpone the development of retinal degener...... hiện toàn bộ
Abdominoplasty Panniculus as a Source for Human Acellular Dermis: A Preliminary Report
Springer Science and Business Media LLC - Tập 19 - Trang 727-738 - 2022
Nayef Abdulrahman. Louri, Nigamananda Dey, Rashed N. AlHasan, Safa Hassan Abdulla, Mohamed Elsakka, Rasheeqa Gulreez, Abdulla Hassan Darwish, Balamuthu Kadalmani, Khalid Bin Ali Al Khalifa
In extensive deep dermal burn injuries, split-thickness skin graft (STSG) has been the most preferred treatment option for resurfacing burn wounds. A thick split-thickness skin graft is ideal for preventing graft contracture but is associated with delayed donor healing and the lack of adequate donor skin. When applied with STSG, the dermal substitutes offer better-reconstructed skin than STSG alon...... hiện toàn bộ
Dental Pulp Stem Cells: Current Advances in Isolation, Expansion and Preservation
Springer Science and Business Media LLC - Tập 14 - Trang 333-347 - 2017
Beatriz A. Rodas-Junco, Claudia Villicaña
Dental pulp stem cells (DPSCs) are mesenchymal stem cells with high self-renewal potential that have the ability to differentiate into several cell types. Thus, DPSCs have become a promising source of cells for several applications in regenerative medicine, tissue engineering, and stem cell therapy. Numerous methods have been reported for the isolation, expansion, and preservation of DPSCs. Howeve...... hiện toàn bộ
Reduced Expression of YAP in Dermal Fibroblasts is Associated with Impaired Wound Healing in Type 2 Diabetic Mice
Springer Science and Business Media LLC - Tập 14 - Trang 49-55 - 2017
Jinyeong Yu, Sanghyuk Choi, Jihyun Um, Ki-Sook Park
Dermal fibroblasts play essential roles in wound healing and their dysfunction has been shown to be associated with impaired wound healing in diabetes. In the present study, we aimed at investigating whether Yes-associated protein (YAP), a mediator of mechanotransduction in dermal fibroblasts, is associated with impaired wound healing in diabetic mice. Compared with that in the control, the rate o...... hiện toàn bộ
Applications of Computer Modeling and Simulation in Cartilage Tissue Engineering
Springer Science and Business Media LLC - - 2020
Daniel P. Pearce, Sarah Fischer, Fatama Huda, Akbar Vahdati
In Vivo Safety and Regeneration of Long-Term Transported Amniotic Fluid Stem Cells for Renal Regeneration
Springer Science and Business Media LLC - Tập 16 - Trang 81-92 - 2018
Na-hee Yu, So Young Chun, Yun-Sok Ha, Hyun Tae Kim, Eugene Lih, Dae Hwan Kim, Jeongshik Kim, Jae-Wook Chung, Phil Hyun Song, Eun Sang Yoo, Sung Kwang Chung, Dong Keun Han, Bum Soo Kim, Tae Gyun Kwon
Despite major progress in stem cell therapy, our knowledge of the characteristics and tissue regeneration potency of long-term transported cells is insufficient. In a previous in vitro study, we established the optimal cell transport conditions for amniotic fluid stem cells (AFSCs). In the present study, the target tissue regeneration of long-term transported cells was validated in vivo. For renal...... hiện toàn bộ
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