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Intra-articular Injection of Chitosan-Based Supramolecular Hydrogel for Osteoarthritis Treatment
Springer Science and Business Media LLC - Tập 18 - Trang 113-125 - 2021
Donggang Mou, Qunying Yu, Jimei Zhang, Jianping Zhou, Xinmin Li, Weiyi Zhuang, Xuming Yang
Pain and cartilage destruction caused by osteoarthritis (OA) is a major challenge in clinical treatment. Traditional intra-articular injection of hyaluronic acid (HA) can relieve the disease, but limited by the difficulty of long-term maintenance of efficacy. In this study, an injectable and self-healing hydrogel was synthesized by in situ crosslinking of N-carboxyethyl chitosan (N-chitosan), adip...... hiện toàn bộ
Adaptation of Human Testicular Niche Cells for Pluripotent Stem Cell and Testis Development Research
Springer Science and Business Media LLC - - 2020
Marina V. Pryzhkova, Philip W. Jordan
Preparation and Characterization of Human Adipose Tissue-Derived Extracellular Matrix, Growth Factors, and Stem Cells: A Concise Review
Springer Science and Business Media LLC - Tập 16 - Trang 385-393 - 2019
So Young Chun, Jeong Ok Lim, Eun Hye Lee, Man-Hoon Han, Yun-Sok Ha, Jun Nyung Lee, Bum Soo Kim, Min Jeong Park, MyungGu Yeo, Bongsu Jung, Tae Gyun Kwon
Human adipose tissue is routinely discarded as medical waste. However, this tissue may have valuable clinical applications since methods have been devised to effectively isolate adipose-derived extracellular matrix (ECM), growth factors (GFs), and stem cells. In this review, we analyze the literature that devised these methods and then suggest an optimal method based on their characterization resu...... hiện toàn bộ
Near-infrared Transillumination and Photodynamic Therapy Using Hypericin in Animal Laryngeal Tumors
Springer Science and Business Media LLC - Tập 18 - Trang 941-951 - 2021
Min-Jung Jung, Daa Young Kwon, Chulho Oak, Haeyoung Lee, Sung Won Kim, Yeh-Chan Ahn, Jun Hyeong Kim, Hyun Wook Kang
We aimed to validate a pilot study of photodiagnosis using near infrared (NIR) transillumination and assess the clinical efficacy of hypericin-mediated photodynamic therapy (HYP-PDT) in a rabbit laryngeal cancer model in order to develop a novel therapeutic modality with complete remission and preservation of the functional organ. (1) In vitro study: VX tumor cells were subcultured and subjected t...... hiện toàn bộ
Abdominoplasty Panniculus as a Source for Human Acellular Dermis: A Preliminary Report
Springer Science and Business Media LLC - Tập 19 - Trang 727-738 - 2022
Nayef Abdulrahman. Louri, Nigamananda Dey, Rashed N. AlHasan, Safa Hassan Abdulla, Mohamed Elsakka, Rasheeqa Gulreez, Abdulla Hassan Darwish, Balamuthu Kadalmani, Khalid Bin Ali Al Khalifa
In extensive deep dermal burn injuries, split-thickness skin graft (STSG) has been the most preferred treatment option for resurfacing burn wounds. A thick split-thickness skin graft is ideal for preventing graft contracture but is associated with delayed donor healing and the lack of adequate donor skin. When applied with STSG, the dermal substitutes offer better-reconstructed skin than STSG alon...... hiện toàn bộ
Electroporation of AsCpf1/RNP at the Zygote Stage is an Efficient Genome Editing Method to Generate Knock-Out Mice Deficient in Leukemia Inhibitory Factor
Springer Science and Business Media LLC - Tập 17 - Trang 45-53 - 2019
Yeon Sun Kim, Gyeong Ryeong Kim, Mira Park, Seung Chel Yang, So Hee Park, Ji Eun Won, Ju Hee Lee, Ha Eun Shin, Haengseok Song, Hye-Ryun Kim
CRISPR/Cpf1 is a class II, type V RNA-guided endonuclease that is distinct from the type II CRISPR/Cas9 nuclease, widely used for genome editing. Cpf1 is a smaller and simpler endonuclease than Cas9, overcoming some limitations of the CRISPR/Cas9 system. The applications of CRISPR to rodent embryos for the production of knock-out (KO) mice have been achieved mainly by microinjection, which require...... hiện toàn bộ
Three-Dimensional Cell Cultures as a Research Platform in Lung Diseases and COVID-19
Springer Science and Business Media LLC - Tập 18 - Trang 735-745 - 2021
Felipe Allan da Silva da Costa, Murilo Racy Soares, Maria José Malagutti-Ferreira, Gustavo Ratti da Silva, Francislaine Aparecida dos Reis Lívero, João Tadeu Ribeiro-Paes
Chronic respiratory diseases (CRD) are a major public health problem worldwide. In the current epidemiological context, CRD have received much interest when considering their correlation with greater susceptibility to SARS-Cov-2 and severe disease (COVID-19). Increasingly more studies have investigated pathophysiological interactions between CRD and COVID-19. Animal experimentation has decisively...... hiện toàn bộ
The effect of gamma radiation sterilization on dental biomaterials
Springer Science and Business Media LLC - Tập 11 - Trang 341-349 - 2014
N. Selcan Türker, A. Yekta Özer, Burak Kutlu, Rahime Nohutcu, Arzu Sungur, Hasan Bilgili, Melike Ekizoglu, Meral Özalp
Biomaterials are used in the field of bone and tissue engineering, orthopaedics and dentistry. Dental biomaterials including commercially available biodegradable materials act as physical barriers to help quicker healing while stimulating the regeneration of periodontal tissues, which is defined as Guided Tissue Regeneration (GTR). Amongst natural and synthetic biomaterials, collagen and aliphatic...... hiện toàn bộ
Transplantation of Differentiated Tonsil-Derived Mesenchymal Stem Cells Ameliorates Murine Duchenne Muscular Dystrophy via Autophagy Activation
Springer Science and Business Media LLC - Tập 19 - Trang 1283-1294 - 2022
Saeyoung Park, Soyeon Jeong, Yu Hwa Nam, Yoonji Yum, Sung-Chul Jung
Skeletal muscles play many important roles in the human body and any malfunction or disorder of the skeletal muscles can lead to a reduced quality of life. Some skeletal dysfunctions are acquired, such as sarcopenia but others are congenital. Duchenne muscular dystrophy (DMD) is one of the most common forms of hereditary muscular dystrophy and is caused by a deficiency of the protein, Dystrophin. ...... hiện toàn bộ
Characterization of a hybrid bone substitute composed of polylactic acid tetrapod chips and hydroxyapatite powder
Springer Science and Business Media LLC - Tập 10 Số 2 - Trang 71-76 - 2013
So Hee Park, Sung-Hee Park, Dae Sung Park, Yun Gyeong Kang, Ji Won Shin, Hyung Keun Kim, Taek Rim Yoon, Jung-Woog Shin
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