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Signal Transducer and Activator of Transcription 4-Induced Up-Regulated LINC01278 Enhances Proliferation and Invasion of Non-Small Cell Lung Cancer Cells via the MicroRNA-877-5p/Activating Transcription Factor 4 Axis
Springer Science and Business Media LLC - - 2024
The purpose of this study was to investigate the specific effects of signal transducer and activator of transcription 4 (STAT4)-induced long intergenic nonprotein coding RNA 1278 (LINC01278) on the growth of non-small cell lung cancer (NSCLC) cells involved in the microRNA (miR)-877-5p/activated transcription factor 4 (ATF4) axis. NSCLC tumor tissue and adjacent normal tissue were collected. Human......
Three-Dimensional Bioprinting Scaffolding for Nasal Cartilage Defects: A Systematic Review
Springer Science and Business Media LLC - Tập 18 - Trang 343-353 - 2021
In recent years, three-dimensional (3D)-printing of tissue-engineered cartilaginous scaffolds is intended to close the surgical gap and provide bio-printed tissue designed to fit the specific geometric and functional requirements of each cartilage defect, avoiding donor site morbidity and offering a personalizing therapy. To investigate the role of 3D—bioprinting scaffolding for nasal cartilage de......
Enrichment and In Vitro Culture of Spermatogonial Stem Cells from Pre-Pubertal Monkey Testes
Springer Science and Business Media LLC - Tập 14 - Trang 557-566 - 2017
Spermatogonial stem cells (SSCs) are essential for spermatogenesis throughout the lifespan of the male. However, the rarity of SSCs has raised the need for an efficient selection method, but little is known about culture conditions that stimulate monkey SSC proliferation in vitro. In this study, we report the development of effective enrichment techniques and in vitro culturing of germ cells from ......
Indirect co-culture of stem cells from human exfoliated deciduous teeth and oral cells in a microfluidic platform
Springer Science and Business Media LLC - Tập 13 - Trang 428-436 - 2016
Oral epithelial-mesenchymal interactions play a key role in tooth development and assist differentiation of dental pulp. Many epithelial and mesenchymal factors in the microenvironment influence dental pulp stem cells to differentiate and regenerate. To investigate the interaction between oral cells during differentiation, we designed a microfluidic device system for indirect co-culture. The syste......
Intra-articular Injection of Chitosan-Based Supramolecular Hydrogel for Osteoarthritis Treatment
Springer Science and Business Media LLC - Tập 18 - Trang 113-125 - 2021
Pain and cartilage destruction caused by osteoarthritis (OA) is a major challenge in clinical treatment. Traditional intra-articular injection of hyaluronic acid (HA) can relieve the disease, but limited by the difficulty of long-term maintenance of efficacy. In this study, an injectable and self-healing hydrogel was synthesized by in situ crosslinking of N-carboxyethyl chitosan (N-chitosan), adip......
A Non-woven Path: Electrospun Poly(lactic acid) Scaffolds for Kidney Tissue Engineering
Springer Science and Business Media LLC - Tập 15 Số 3 - Trang 301-310 - 2018
Ascorbic Acid 2-Phosphate Releasing Supercritically Foamed Porous Poly-L-Lactide-Co-ε-Caprolactone Scaffold Enhances the Collagen Production of Human Vaginal Stromal Cells: A New Approach for Vaginal Tissue Engineering
Springer Science and Business Media LLC - - Trang 1-16 - 2023
The reconstructive surgery of vaginal defects is highly demanding and susceptible to complications, especially in larger defects requiring nonvaginal tissue grafts. Thus, tissue engineering-based solutions could provide a potential approach to the reconstruction of vaginal defects. Here, we evaluated a novel porous ascorbic acid 2-phosphate (A2P)-releasing supercritical carbon dioxide foamed poly-......
A tissue-engineered conduit for urinary diversion using bone marrow mesenchymal stem cells and bladder acellular matrix
Springer Science and Business Media LLC - Tập 12 - Trang 188-194 - 2015
Ileal conduits are commonly used in bladder cancer treatment and in pediatric patients who require urinary diversion surgeries. We constructed a tissue-engineered conduit using bone marrow mesenchymal stem cells (BMSCs) and a bladder acellular matrix (BAM) and transplanted it into rabbits for urinary diversion to evaluate the feasibility of its clinical application. Rabbit BMSCs were isolated, exp......
Adaptation of Human Testicular Niche Cells for Pluripotent Stem Cell and Testis Development Research
Springer Science and Business Media LLC - - 2020
The effect of fibroblast growth factor and periodontal ligament fibroblast-conditioned medium on fibroblast-related gene expression in bone marrow stromal cells
Springer Science and Business Media LLC - Tập 10 - Trang 176-182 - 2013
Periodontal ligament fibroblasts (PDLFs) are essential to most periodontal tissue regeneration processes. This study evaluated the potential of fibroblast growth factor (FGF) and PDLF-conditioned media to modulate fibroblast differentiation from bone marrow stromal cells (BMSCs) that were obtained from mongrel dogs. The medium obtained from culture of periodontal ligament fibroblasts of dogs was u......
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