Abstract Background A shortened reproductive period and earlier menopause have
been associated with type 2 diabetes. Growth differentiation factor 9(GDF9) and
bone morphogenetic protein 15 (BMP15) gene mutations have been associated with
earlier menopause. Therefore, this study aimed to evaluate the association
between BMP15 and GDF9 mutations with impairing female fecundity in diabetic
patients. ... hiện toàn bộ
Abstract Background The embryology laboratory remains one of the primary factors
influencing the overall performance of the IVF clinic. Clinical embryology,
however, has undergone remarkable advancements over the last decade. These
developments in both practice and education have been driven together by science
and technology. Main body The changes in clinical embryology practice have
created a si... hiện toàn bộ
Emad Abdelrahman Eltemamy, Sameh Salama, S. A. Salem, Mazen Abdel-Rasheed, Ehab Salama, Sherif Elsirgany, Tamer El-Nahas
AbstractBackgroundMany issues need to be studied regarding pregnant women during
the SARS-CoV-2 (COVID-19) infection pandemic. The aim of this study was to
assess fetal growth, fetal well-being, and any observed gross anomalies that may
follow SARS-CoV-2 infection in Egyptian pregnant women. During fetal anomaly
scan at 22 weeks, we compared 30 pregnant women with a history of SARS-CoV-2
infection... hiện toàn bộ
Diogo Edele Dos Santos, Tamy Colonetti, Lídia Rosi Medeiros, Maria Laura Rodrigues Uggioni, Antônio José Grande, Maria Inês da Rosa
AbstractA recent systematic review with meta-analysis performed by Tiwari et al.
(Middle East Fertil Soc J 26:44, 2021) suggested that coronavirus disease 2019
(COVID-19) affects both semen parameters and sexual hormones. However, we have
observed a few inconsistencies in their systematic review methods and their
synthesis of results (meta-analysis), which would have impacted their results.
Abstract Background Epigenetics refers to an alteration in gene expression
without alteration in the sequence of DNA and this process may be affected by
environmental factors and lifestyle like cigarette smoking. This study was
designed to evaluate the potential effect of cigarette smoking on the global DNA
methylation status and the transcription level of protamine 1 and protamine 2 in
human sper... hiện toàn bộ
Anna Gideon Kasililika, Akin‐Tunde A. Odukogbe, Magbagbeola David Dairo, Belinda Balandya, Emmanuel Kulwa Bunuma
Abstract Background Female infertility is a public health problem, contributing
to 65.9% of infertility in Tanzania. Lifestyle and oxidative stress (OS) have
been suggested to affect female fertility; however, there are limited and
controversial reports. This study aimed to determine the lifestyle and OS status
of fertile and infertile women and relate lifestyle and OS to female
infertility. The s... hiện toàn bộ
Abstract Background Vitamin D3 (Vit.D3) is an antioxidant that can improve sperm
motility. However, the specific mechanisms of Vit.D3’s effect on sperm are not
yet elucidated. Since heat shock protein 70 (HSP70) and oxidative stress (OS)
are effective in sperm motility and it has been shown that vitamin D3 is
associated with these factors, thus this pilot study evaluated the effects of
Vit.D3 on H... hiện toàn bộ
Mustafa Ali, Aruna Kumari Hira, Haris Jawaid, Faiza Zakaria, Zehra Somjee
Abstract Background Heavy menstrual bleeding (HMB) is a common clinical finding
in patients with uterine leiomyomas that can negatively impact their quality of
life. Recently, a novel oral GnRH-antagonist (elagolix) has emerged as a
possible therapeutic agent for this ailment. Herein data was pooled from
clinical trials assessing the safety and efficacy of elagolix with and without
add-back therap... hiện toàn bộ
Shofwal Widad, Detty Siti Nurdiati, Sarrah Ayuandari, Kuky Cahya Hamurajib, Muhammad Dimas Reza Rahmana, Nurulita Ainun Alma, Agung Dewanto
Abstract Background Ovarian tissue vitrification is an alternative fertility
preservation procedure for young female patients prior to gonadotoxic treatment.
Primordial follicle loss might be a potential issue for vitrification and
transplantation procedures. This study aimed to evaluate primordial follicle
density and deoxyribonucleic acid (DNA) fragmentation in each stage of the
preservation pro... hiện toàn bộ
Abstract Background The effect of obesity on IVF consequences is still
debatable. Main body Obesity is linked to a greater likelihood of maternal and
fetal complications all through gestation, including miscarriage, premature
births, fetal demise, and adverse pregnancy outcomes. There was no increase in
chromosomal abnormality percentages with increasing body mass index (BMI),
implying that poor o... hiện toàn bộ