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A weakly supervised deep learning model integrating noncontrasted computed tomography images and clinical factors facilitates haemorrhagic transformation prediction after intravenous thrombolysis in acute ischaemic stroke patients
Springer Science and Business Media LLC - Tập 22 - Trang 1-17 - 2023
Haemorrhage transformation (HT) is a serious complication of intravenous thrombolysis (IVT) in acute ischaemic stroke (AIS). Accurate and timely prediction of the risk of HT before IVT may change the treatment decision and improve clinical prognosis. We aimed to develop a deep learning method for predicting HT after IVT for AIS using noncontrast computed tomography (NCCT) images. We retrospectivel......
Hypoxia-inducible transcription factor-1α inhibition by topotecan protects against lipopolysaccharide-induced inflammation and apoptosis of cardiomyocytes
Springer Science and Business Media LLC - - 2021
Myocarditis, an inflammatory disease of the myocardium, is a serious hazard to human life due to the expansion of inflammatory lesions in the myocardium. The aim of this study was to investigate the role of hypoxia-inducible transcription factor (HIF)-1α and its inhibitor topotecan in the pathogenesis of myocarditis. H9c2 cardiomyoblasts was stimulated with lipopolysaccharide (LPS) to simulate myo......
Stiffness and ultimate load of osseointegrated prosthesis fixations in the upper and lower extremity
Springer Science and Business Media LLC - Tập 12 - Trang 1-13 - 2013
Techniques for the skeletal attachment of amputation-prostheses have been developed over recent decades. This type of attachment has only been performed on a small number of patients. It poses various potential advantages compared to conventional treatment with a socket, but is also associated with an increased risk of bone or implant-bone interface fracture in the case of a fall. We therefore inv......
"Handbook of biomedical optics", edited by David A. Boas, Constantinos Pitris, and Nimmi Ramanujam
Springer Science and Business Media LLC - Tập 11 - Trang 1-5 - 2012
David A. Boas, Constantinos Pitris, and Nimmi Ramanujam, Eds.:
Handbook of Biomedical Optics
CRC Press, Taylor and Francis Group, Boca Raton, London, New York, 2011 ISBN: 978-1-4200-9036-9 (Hardback), 787 pages
Is there any advantage of using stand-alone cages? A numerical approach
Springer Science and Business Media LLC - Tập 18 - Trang 1-17 - 2019
Segment fusion using interbody cages supplemented with pedicle screw fixation is the most common surgery for the treatment of low back pain. However, there is still much controversy regarding the use of cages in a stand-alone fashion. The goal of this work is to numerically compare the influence that each surgery has on lumbar biomechanics. A non-linear FE model of the whole lumbar spine was devel......
Comparative study of optical coherence tomograph and histological images of eustachian tube nasopharyngeal region and adjacent structures in vivo and ex-vivo miniature pigs
Springer Science and Business Media LLC - Tập 22 - Trang 1-11 - 2023
Optical Coherence Tomograph (OCT) imaging technology can be used to examine, in vivo, the human ET. At present, it is impossible to achieve the OCT scanning vivo and ex vivo in the same individual human body, or study the consistency between OCT images and histological images of the eustachian tube nasopharyngeal region and adjacent structures. The aim of this study was to determine the consistenc......
Instantaneous radiated power of brain activity: application to prepulse inhibition and facilitation for body dysmorphic disorder
Springer Science and Business Media LLC - Tập 20 - Trang 1-21 - 2021
Global measures of neuronal activity embrace the advantage of a univariate, holistic and unique description of brain activity, reducing the spatial dimensions of electroencephalography (EEG) analysis at the cost of lower precision in localizing effects. In this work, the instantaneous radiated power (IRP) is proposed as a new whole-brain descriptor, reflecting the cortical activity from an exclusi......
Computational flow cytometric analysis to detect epidermal subpopulations in human skin
Springer Science and Business Media LLC - Tập 20 Số 1 - Trang 1-12 - 2021
The detection and dissection of epidermal subgroups could lead to an improved understanding of skin homeostasis and wound healing. Flow cytometric analysis provides an effective method to detect the surface markers of epidermal cells while producing high-dimensional data files. A 9-color flow cytometric panel was optimized to reveal the heterogeneous subgroups in the epidermis of human skin. The s......
A study of polymerase chain reaction device control via cloud using Firebase Cloud Messaging protocol
Springer Science and Business Media LLC - - 2018
In this paper, we propose a system for data monitoring and control of polymerase chain reaction (PCR) externally. PCR is a technique for amplifying a desired DNA molecule by repeatedly synthesizing a specific part of DNA sequence. Currently, commercially available systems are standalone systems or operate PCR devices through a computer in the vicinity of devices for control purposes. These systems......
Design optimization of stent and its dilatation balloon using kriging surrogate model
Springer Science and Business Media LLC - Tập 16 - Trang 1-17 - 2017
Although stents have great success of treating cardiovascular disease, it actually undermined by the in-stent restenosis and their long-term fatigue failure. The geometry of stent affects its service performance and ultimately affects its fatigue life. Besides, improper length of balloon leads to transient mechanical injury to the vessel wall and in-stent restenosis. Conventional optimization meth......
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