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Effect of serum 25-hydroxyvitamin D concentrations on skeletal mineralization in black and white women
Springer Science and Business Media LLC - Tập 39 - Trang 843-850 - 2021
Shijing Qiu, Sudhaker D. Rao
There is controversy over the adverse effect of vitamin D deficiency on bone mineralization. The purpose of this study was to determine the ethnical differences in vitamin D and bone mineralization as well as the association between vitamin D deficiency and bone mineralization defects. We examined serum 25-hydroxyvitamin D (25(OH)D) levels and transiliac bone biopsies in 92 healthy black and white...... hiện toàn bộ
CT evaluation of bone fragility 2 years after bariatric surgery: an observational study
Springer Science and Business Media LLC - Tập 41 - Trang 105-112 - 2022
Marine Fauny, Marion Halin, Edem Allado, Didier Quilliot, Laurent Brunaud, Eliane Albuisson, Isabelle Chary-Valckenaere, Damien Loeuille
The objectives were to evaluate bone fragility on computed tomography (CT) in patients with obesity before and 2 years after bariatric surgery and to identify risk factors for a decrease in the scanographic bone attenuation coefficient of the first lumbar vertebra (SBAC-L1). Patients with obesity who underwent bariatric surgery and CT before and 2 years (± 6 months) after bariatric surgery were in...... hiện toàn bộ
Association of body mass index and waist circumference with osteocalcin and C-terminal telopeptide in Iranian elderly: results from a cross-sectional study
Springer Science and Business Media LLC - Tập 37 - Trang 179-184 - 2018
Hamed Kord-Varkaneh, Hadith Tangestani, Sara Mansouri, Abbas Rahimi-Foroushani, Sakineh Shab-Bidar
There is no agreement on the role of obesity as a protection or unfavorable factor on bone. In the present study, the association of body mass index (BMI) and waist circumference (WC) with osteocalcin, C-terminal telopeptide of type 1 collagen (CTX-I), highly sensitive C-reactive protein (hs-CRP), parathormon (PTH) and 25-hydroxyvitamin D (25(OH)D) in elderly people was investigated. This cross-se...... hiện toàn bộ
Calcium restriction during lactation has minimal effects on post-weaning mineral metabolism and bone recovery
Springer Science and Business Media LLC - Tập 37 - Trang 648-657 - 2018
Ryan D. Ross, Matthew J. Meagher, D. Rick Sumner
Dietary calcium (Ca) restriction during lactation in the rat, which induces intra-cortical and endocortical remodeling, has been proposed as a model to study bone matrix maturation in the adult skeleton. The purpose of this study was to assess the effects of dietary Ca restriction during lactation on post-weaning mineral metabolism and bone formation. Mated female Sprague–Dawley rats were randomiz...... hiện toàn bộ
Effects of additional resistance training during diet-induced weight loss on bone mineral density in overweight premenopausal women
Springer Science and Business Media LLC - Tập 26 - Trang 172-177 - 2008
Yoshio Nakata, Kazunori Ohkawara, Dong Jun Lee, Tomohiro Okura, Kiyoji Tanaka
Bone loss accompanies a diet-induced weight loss and could be prevented with a combination of exercises. This study was conducted to examine the effects of additional resistance training during diet-induced weight loss on whole-body and selected regional bone mineral density (BMD). The participants of a 14-week weight-loss study were 42 overweight premenopausal Japanese women who were randomly pla...... hiện toàn bộ
The effects of calcitonin on bone resorption in hyperthyroidism: a placebo-controlled clinical study
Springer Science and Business Media LLC - Tập 22 - Trang 90-93 - 2004
MÜfide Nuran AkÇay, GÜngÖr AkÇay, Habib Bİlen
The effects of intranasal calcitonin on bone metabolism were investigated in patients with hyperthyroidism. Urinary deoxypyridinoline (uDPD) levels were measured as a bone turnover marker and lumbar spine (L2) bone mineral density (BMD) was measured by dual-energy X-ray absorptiometry (DEXA) in 7 patients who were given only antithyroid drug (group 1), in 10 patients who were given antithyroid dru...... hiện toàn bộ
Lack of association between vitamin D receptor gene polymorphism (BsmI) and osteomalacia
Springer Science and Business Media LLC - Tập 22 - Trang 39-43 - 2004
Hakkı Kahraman, Belgin SÜsleyici Duman, Faruk AlagÖl, Refik Tanakol, Selma Yılmazer
Vitamin D receptor (VDR) gene polymorphism has been reported to be a determinant of bone formation and intestinal calcium absorption. We carried out this study to assess the role of VDR gene polymorphism in the pathogenesis of osteomalacia. We investigated BsmI polymorphisms in the gene encoding the 1,25 dihydroxyvitamin D receptor in 38 patients with osteomalacia and 31 healthy controls, along wi...... hiện toàn bộ
Effect of etidronate on three-dimensional trabecular structure in ovariectomized or sciatic neurectomized rats
Springer Science and Business Media LLC - Tập 22 - Trang 335-340 - 2004
Akifumi Nishida, Masako Ito, Masataka Uetani, Tatsuo Nakayama, Tomoyuki Tanaka
The purpose of this study was to evaluate the effect of etidronate (EHDP) on three-dimensional (3D) trabecular structure in ovariectomized (OVX) and sciatic neurectomized (NX) rats. Eight-week-old female Lewis rats received ovariectomy (n = 19) or sham operation (OVX-sham; n = 10). OVX rats received either vehicle (OVX-control; n = 9) or EHDP (OVX-EHDP; n = 10). Eight-week-old female Lewis rats re...... hiện toàn bộ
Rheumatoid arthritis-related antigen 47 kDa (RA-A47) is a product of colligin-2 and acts as a human HSP47
Springer Science and Business Media LLC - Tập 18 - Trang 328-334 - 2000
Takako Hattori, Kojiro Takahashi, Yasutaka Yutani, Takuo Fujisawa, Tohru Nakanishi, Masaharu Takigawa
We previously isolated RA-A47, which is recognized as an antigen of rheumatoid arthritis (RA), from a human chondrosarcoma-derived cell line (HCS-2/8). The N-terminal 21-amino-acid sequence of RA-A47 had 81% homology to the deduced amino acid sequence of the human heat-shock protein (HSP) 47 gene, the colligin gene, and 100% homology to that of the colligin-2 gene. Moreover, as is HSP47, RA-A47 ...... hiện toàn bộ
Expression of bone resorption genes in osteoarthritis and in osteoporosis
Springer Science and Business Media LLC - Tập 25 - Trang 219-225 - 2007
Darja Bitenc Logar, Radko Komadina, Janez Preželj, Barbara Ostanek, Zoran Trošt, Janja Marc
Cathepsin K and MMP-9 are considered to be the most abundant proteases in osteoclasts. TRAP is a marker for osteoclasts, and there is increasing evidence of its proteolytic role in bone resorption. RANKL is a recently discovered regulator of osteoclast maturation and activity and induces expression of many genes. This study compared cathepsin K, MMP-9, TRAP, RANKL, OPG, and osteocalcin gene expres...... hiện toàn bộ
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