Is the Alzheimer’s disease cortical thickness signature a biological marker for memory?Springer Science and Business Media LLC - Tập 10 - Trang 517-523 - 2015
Edgar Busovaca, Molly E. Zimmerman, Irene B. Meier, Erica Y. Griffith, Stuart M. Grieve, Mayuresh S. Korgaonkar, Leanne M. Williams, Adam M. Brickman
Recent work suggests that analysis of the cortical thickness in key brain regions can be used to identify individuals at greatest risk for development of Alzheimer’s disease (AD). It is unclear to what extent this “signature” is a biological marker of normal memory function – the primary cognitive domain affected by AD. We examined the relationship between the AD signature biomarker and memory fun...... hiện toàn bộ
Atrophy patterns in hippocampus and amygdala subregions of depressed patients with Parkinson's diseaseSpringer Science and Business Media LLC - - Trang 1-10 - 2024
Mingrui Qu, Bingbing Gao, Yuhan Jiang, Yuan Li, Chenhui Pei, Lizhi Xie, Yukun Zhang, Qingwei Song, Yanwei Miao
We aimed to explore the subregional atrophy patterns of the amygdala and hippocampus in Parkinson's disease (PD) with depression and their correlation with the severity of the depressive symptom. MRI scans were obtained for 34 depressed PD patients (DPD), 22 nondepressed PD patients (NDPD), and 28 healthy controls (HC). Amygdala and hippocampal subregions were automatically segmented, and the inte...... hiện toàn bộ
Neurofunctional characteristics of executive control in older people with HIV infection: a comparison with Parkinson’s diseaseSpringer Science and Business Media LLC - Tập 16 - Trang 1776-1793 - 2022
Eva M. Müller-Oehring, Jui-Yang Hong, Kathleen L. Poston, Helen M. Brontë-Stewart, Edith V. Sullivan, Lawrence McGlynn, Tilman Schulte
Expression of executive dysfunctions is marked by substantial heterogeneity in people living with HIV infection (PLWH) and attributed to neuropathological degradation of frontostriatal circuitry with age and disease. We compared the neurophysiology of executive function in older PLWH and Parkinson’s disease (PD), both affecting frontostriatal systems. Thirty-one older PLWH, 35 individuals with PD,...... hiện toàn bộ
Structural brain network connectivity in trichotillomania (hair-pulling disorder)Springer Science and Business Media LLC - Tập 17 Số 4 - Trang 395-402 - 2023
Annerine Roos, Jean‐Paul Fouché, Dan J. Stein, Christine Löchner
AbstractNeuroimaging studies suggest involvement of frontal, striatal, limbic and cerebellar regions in trichotillomania, an obsessive-compulsive related disorder. However, findings regarding the underlying neural circuitry remains limited and inconsistent. Graph theoretical analysis offers a way to identify structural brain networks in trichotillomania. T1-weighte...... hiện toàn bộ
Diffusion kurtosis imaging tractography reveals disrupted white matter structural networks in children with obstructive sleep apnea syndromeSpringer Science and Business Media LLC - Tập 18 - Trang 92-105 - 2023
Yanhua Li, Hongwei Wen, Wenfeng Li, Yun Peng, Hongbin Li, Jun Tai, Tingting Ji, Lin Mei, Yue Liu
To assess the disruptions of brain white matter (WM) structural network in children with obstructive sleep apnea (OSA) using diffusion kurtosis imaging (DKI). We use DKI tractography to construct individual whole-brain, region-level WM networks in 40 OSA and 28 healthy children. Then, we apply graph theory approaches to analyze whether OSA children would show altered global and regional network to...... hiện toàn bộ
The fMRI correlates of visuo-spatial abilities: sex differences and gender dysphoriaSpringer Science and Business Media LLC - Tập 16 - Trang 955-964 - 2022
Gioele Gavazzi, Alessandra Daphne Fisher, Stefano Orsolini, Andrea Bianchi, Alessia Romani, Fiorenza Giganti, Fabio Giovannelli, Jiska Ristori, Francesca Mazzoli, Mario Maggi, Maria Pia Viggiano, Mario Mascalchi
The contribution of brain regions to visuospatial abilities according to sex differences and gender identity is inconsistently described. One potential explaining factor may be the different tasks employed requiring a variable load of working memory and other cognitive resources. Here we asked to 20 cis and 20 transgender participants to undergo functional Magnetic Resonance Imaging during perform...... hiện toàn bộ
Modeling motor task activation from resting-state fMRI using machine learning in individual subjectsSpringer Science and Business Media LLC - Tập 15 - Trang 122-132 - 2020
Chen Niu, Alexander D. Cohen, Xin Wen, Ziyi Chen, Pan Lin, Xin Liu, Bjoern H. Menze, Benedikt Wiestler, Yang Wang, Ming Zhang
Resting-state functional MRI (rs-fMRI) has provided important insights into brain physiology. It has become an increasingly popular method for presurgical mapping, as an alternative to task-based functional MRI wherein the subject performs a task while being scanned. However, there is no commonly acknowledged gold standard approach for detecting eloquent brain areas using rs-fMRI data in clinical ...... hiện toàn bộ
Intrinsic network connectivity and own body perception in gender dysphoriaSpringer Science and Business Media LLC - Tập 11 - Trang 964-976 - 2016
Jamie D. Feusner, Andreas Lidström, Teena D. Moody, Cecilia Dhejne, Susan Y. Bookheimer, Ivanka Savic
Gender dysphoria (GD) is characterized by incongruence between one’s identity and gender assigned at birth. The biological mechanisms of GD are unclear. We investigated brain network connectivity patterns involved in own body perception in the context of self in GD. Twenty-seven female-to-male (FtM) individuals with GD, 27 male controls, and 27 female controls underwent resting state fMRI. We comp...... hiện toàn bộ
Mental fatigue after mild traumatic brain injury: a 3D-ASL perfusion studySpringer Science and Business Media LLC - Tập 10 - Trang 857-868 - 2016
Kai Liu, Bo Li, Shaowen Qian, Qingjun Jiang, Li Li, Wei Wang, Gaiyun Zhang, Yajuan Sun, Gang Sun
Our purpose was to evaluate mental fatigue associated with mild traumatic brain injury (MTBI) and investigate the underlying neurological mechanisms. We used a 20-min psychomotor vigilance test (PVT) related ASL-fMRI to evaluate mental fatigue in 25 MTBI patients in acute phase, 21 MTBI patients in chronic phase, and 20 healthy subjects. Mental fatigue in patients in acute phase was more severe th...... hiện toàn bộ