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Asymmetric alterations of white matter integrity in patients with insomnia disorder
Springer Science and Business Media LLC - Tập 16 - Trang 389-396 - 2021
Despite the adverse consequences of insomnia disorder for both individuals and society, the underlying neurobiological processes are poorly understood. The purpose was to further understand the alterations of white matter tracts in patients with insomnia and their association with sleep variables and also to determine if diffusion tensor imaging measures would be a useful disease marker. Twenty-si...... hiện toàn bộ
Blood pressure variability and medial temporal atrophy in apolipoprotein ϵ4 carriers
Springer Science and Business Media LLC - Tập 16 - Trang 792-801 - 2021
Blood pressure variability is an emerging risk factor for dementia but relationships with markers of neurodegeneration and Alzheimer’s disease risk are understudied. We investigated blood pressure variability over one year and follow-up medial temporal brain volume change in apolipoprotein ϵ4 carriers and non-carriers, and in those with and without Alzheimer’s disease biomarker abnormality. 1051 A...... hiện toàn bộ
Neuroanatomical substrates of maximizing tendency in decision-making: a voxel-based morphometric study
Springer Science and Business Media LLC - Tập 16 - Trang 1938-1945 - 2022
Maximizing tendency is a central decision-making concept that has increasingly drawn attention from the scientific community. It refers to individuals’ predisposition to look for the best option instead of settling for something that merely passes an internal threshold of acceptability. Although this maximizing strategy intuitively increases individual benefits, it also has been linked to various ...... hiện toàn bộ
Effective connectivity predicts cognitive empathy in cocaine addiction: a spectral dynamic causal modeling study
Springer Science and Business Media LLC - Tập 15 - Trang 1553-1561 - 2020
Social cognition plays a crucial role in the development and treatment of cocaine dependence. However, studies investigating social cognition, such as empathy and its underlying neural basis, are lacking. To explore the neural interactions among reward and memory circuits, we applied effective connectivity analysis on resting-state fMRI data collected from cocaine-dependent subjects. The relations...... hiện toàn bộ
Hormonal factors moderate the associations between vascular risk factors and white matter hyperintensities
Springer Science and Business Media LLC - Tập 17 - Trang 172-184 - 2022
To examine the moderation effects of hormonal factors on the associations between vascular risk factors and white matter hyperintensities in men and women, separately. White matter hyperintensities were automatically segmented and quantified in the UK Biobank dataset (N = 18,294). Generalised linear models were applied to examine (1) the main effects of vascular and hormonal factors on white matte...... hiện toàn bộ
Altered spatio-temporal state patterns for functional dynamics estimation in first-episode drug-naive major depression
Springer Science and Business Media LLC - - 2022
Quantitative prediction of individual cognitive flexibility using structural MRI
Springer Science and Business Media LLC - Tập 13 - Trang 781-788 - 2018
Cognitive flexibility, a core dimension of executive functions, refers to one’s ability to switch between multiple tasks and sets in a quick and flexible manner. However, whether objective neuroimaging can be used to quantitatively predict cognitive flexibility at the individual level remains largely unexplored. High-resolution magnetic resonance imaging data of 100 healthy young participants from...... hiện toàn bộ
Glutamate System Genes Associated with Ventral Prefrontal and Thalamic Volume in Pediatric Obsessive-Compulsive Disorder
Springer Science and Business Media LLC - - 2009
A preliminary investigation of corpus callosum subregion white matter vulnerability and relation to chronic outcome in boxers
Springer Science and Business Media LLC - Tập 14 - Trang 772-786 - 2018
Microstructural neuropathology occurs in the corpus callosum (CC) after repetitive sports concussion in boxers and can be dose-dependent. However, the specificity and relation of CC changes to boxing exposure extent and post-career psychiatric and neuropsychological outcomes are largely unknown. Using deterministic diffusion tensor imaging (DTI) techniques, boxers and demographically-matched, nonc...... hiện toàn bộ
Mapping anticipatory anhedonia: an fMRI study
Springer Science and Business Media LLC - Tập 13 - Trang 1624-1634 - 2019
Anhedonia—broadly defined as loss of interest and/or an inability to experience pleasure—is an important feature of several psychiatric disorders. Research into the clinical presentation and neurobiology of this symptom has identified components related to motivation, learning, anticipation, and experience of pleasure as important constructs that inform therapeutic interventions. The experimental ...... hiện toàn bộ
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