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Is the Alzheimer’s disease cortical thickness signature a biological marker for memory?
Springer Science and Business Media LLC - Tập 10 - Trang 517-523 - 2015
Edgar Busovaca, Molly E. Zimmerman, Irene B. Meier, Erica Y. Griffith, Stuart M. Grieve, Mayuresh S. Korgaonkar, Leanne M. Williams, Adam M. Brickman
Recent work suggests that analysis of the cortical thickness in key brain regions can be used to identify individuals at greatest risk for development of Alzheimer’s disease (AD). It is unclear to what extent this “signature” is a biological marker of normal memory function – the primary cognitive domain affected by AD. We examined the relationship between the AD signature biomarker and memory fun...... hiện toàn bộ
The fMRI correlates of visuo-spatial abilities: sex differences and gender dysphoria
Springer Science and Business Media LLC - Tập 16 - Trang 955-964 - 2022
Gioele Gavazzi, Alessandra Daphne Fisher, Stefano Orsolini, Andrea Bianchi, Alessia Romani, Fiorenza Giganti, Fabio Giovannelli, Jiska Ristori, Francesca Mazzoli, Mario Maggi, Maria Pia Viggiano, Mario Mascalchi
The contribution of brain regions to visuospatial abilities according to sex differences and gender identity is inconsistently described. One potential explaining factor may be the different tasks employed requiring a variable load of working memory and other cognitive resources. Here we asked to 20 cis and 20 transgender participants to undergo functional Magnetic Resonance Imaging during perform...... hiện toàn bộ
Mental fatigue after mild traumatic brain injury: a 3D-ASL perfusion study
Springer Science and Business Media LLC - Tập 10 - Trang 857-868 - 2016
Kai Liu, Bo Li, Shaowen Qian, Qingjun Jiang, Li Li, Wei Wang, Gaiyun Zhang, Yajuan Sun, Gang Sun
Our purpose was to evaluate mental fatigue associated with mild traumatic brain injury (MTBI) and investigate the underlying neurological mechanisms. We used a 20-min psychomotor vigilance test (PVT) related ASL-fMRI to evaluate mental fatigue in 25 MTBI patients in acute phase, 21 MTBI patients in chronic phase, and 20 healthy subjects. Mental fatigue in patients in acute phase was more severe th...... hiện toàn bộ
Prediction of future weight change with the dopamine transporter
Springer Science and Business Media LLC - Tập 13 - Trang 588-593 - 2018
Kyoungjune Pak, Keunyoung Kim, Myung Jun Lee, Jae Meen Lee, Bum Soo Kim, Seong-Jang Kim, In Joo Kim
The brain plays a critical role in controlling and inhibiting pre-potent responses to foods. We investigated the predictive value of dopamine transporter (DAT) availability in the striatum of healthy subjects using 123I-FP-CIT single-photon emission computed tomography (SPECT). In total, 84 participants with available data on their weight for the 60 months after SPECT were included. Specific bindi...... hiện toàn bộ
Individual differences in pain sensitivity in drug-naive patients with major depressive disorder: an fMRI study
Springer Science and Business Media LLC - Tập 15 - Trang 1335-1343 - 2020
Qianmei Hou, Chen Wang, Changyue Hou, Juan Tan, Shaoyue He, Lei Tang, Na Yong, Xianghong Ding, Guohui Jiang, Jixin Liu, Xiaoming Wang
Patients with major depressive disorder (MDD) often report pain; however, the pain-related brain mechanism that contributes to MDD with pain remains largely unclear. In the current study, we aimed to observe the cortical responses by employing fMRI technique combined with thermal stimulation paradigm in 17 major depressive disorder patients with pain (MDDP), 19 major depressive disorder patients w...... hiện toàn bộ
Increased resting state functional irregularity of T2DM brains with high HbA1c: sign for impaired verbal memory function?
Springer Science and Business Media LLC - Tập 15 - Trang 772-781 - 2020
Xin Zhang, Ying Yu, Zhe-Sheng Shi, Ke Xu, Jia-Hao Feng, Ze-Yang Li, Xiang-Nan Zhang, Shu-Ning Shen, Yang Yang, Lin-Feng Yan, Jin Zhang, Qian Sun, Bo Hu, Guang-Bin Cui, Wen Wang
Glycosylated hemoglobin A1c (HbA1c) has been considered as a key contributor to impaired cognition in type 2 diabetes mellitus (T2DM) brains. However, how does it affect the brain and whether the glucose controlling can slow down the process are still unknown. In the current study, T2DM patients with high glycosylated hemoglobin level (HGL) and controls with normal glycosylated hemoglobin level (N...... hiện toàn bộ
Less reduced gray matter volume in the subregions of superior temporal gyrus predicts better treatment efficacy in drug-naive, first-episode schizophrenia
Springer Science and Business Media LLC - Tập 15 - Trang 1997-2004 - 2020
Xilong Cui, Qijian Deng, Bing Lang, Qinji Su, Feng Liu, Zhikun Zhang, Jindong Chen, Jingping Zhao, Wenbin Guo
Decreased gray matter volume (GMV) in the superior temporal gyrus (STG) has been implicated in the neurophysiology of schizophrenia. However, it remains unclear whether volumetric reduction in the subregions of the STG can predict treatment efficacy for schizophrenia. Our cohort included 44 drug-naive, first-episode patients, 42 unaffected siblings and 44 healthy controls. Voxel-based morphometry ...... hiện toàn bộ
Specific cerebellar and cortical degeneration correlates with ataxia severity in spinocerebellar ataxia type 7
Springer Science and Business Media LLC - Tập 10 - Trang 252-257 - 2015
Carlos R. Hernandez-Castillo, Victor Galvez, Rosalinda Diaz, Juan Fernandez-Ruiz
Spinocerebellar ataxia type 7 (SCA7) is a progressive neurodegenerative disorder that is accompanied by loss of motor control and macular degeneration. Previous studies have shown cerebellar and pons atrophy as well as functional connectivity changes across the whole brain. Although different MRI modalities have been used to study the degenerative process, little is known about the relationship be...... hiện toàn bộ
Is bruxism associated with changes in neural pathways? A systematic review and meta-analysis of clinical studies using neurophysiological techniques
Springer Science and Business Media LLC - Tập 16 Số 5 - Trang 2268-2280 - 2022
Boscato, Noéli, Exposto, Fernando, Nascimento, Gustavo G., Svensson, Peter, Costa, Yuri M.
This study aimed to systematically review the literature to identify clinical studies assessing neuroplasticity changes induced by or associated with bruxism or a tooth-clenching task using neurophysiological techniques. Searches were performed in five electronic databases (PubMed, EMBASE, Scopus, Web of Science, and Google Scholar) in April 2020. This review included clinical studies using neurop...... hiện toàn bộ
The functional connectivity in the motor loop of human basal ganglia
Springer Science and Business Media LLC - Tập 11 - Trang 417-429 - 2016
Clara Rodriguez-Sabate, Magdalena Sabate, Catalina Llanos, Ingrid Morales, Alberto Sanchez, Manuel Rodriguez
Basal ganglia interact in a complex way which is still not completely understood. The model generally used to explain basal ganglia interactions is based on experimental data in animals, but its validation in humans has been hampered by methodological restrictions. The time-relationship (partial correlation) of the fluctuations of the blood-oxygen-level-dependent signals recorded in the main basal...... hiện toàn bộ
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