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Classifying the diagnosis of study participants in clinical trials: a structured and efficient approach
Springer Science and Business Media LLC - Tập 4 - Trang 1-9 - 2020
Tjitske S. R. van Engelen, Maadrika M. N. P. Kanglie, Inge A. H. van den Berk, Merel L. J. Bouwman, Hind J. M. Suhooli, Sascha L. Heckert, Jaap Stoker, Patrick M. M. Bossuyt, Jan M. Prins
A challenge in imaging research is a diagnostic classification of study participants. We hypothesised that a structured approach would be efficient and that classification by medical students, residents, and an expert panel whenever necessary would be as valid as classification of all patients by experts. OPTIMACT is a randomised trial designed to evaluate the effectiveness of replacing chest x-ra... hiện toàn bộ
Artificial intelligence for assessment of vascular involvement and tumor resectability on CT in patients with pancreatic cancer
Springer Science and Business Media LLC - Tập 8 - Trang 1-10 - 2024
Jacqueline I. Bereska, Boris V. Janssen, C. Yung Nio, Marnix P. M. Kop, Geert Kazemier, Olivier R. Busch, Femke Struik, Henk A. Marquering, Jaap Stoker, Marc G. Besselink, Inez M. Verpalen
This study aimed to develop and evaluate an automatic model using artificial intelligence (AI) for quantifying vascular involvement and classifying tumor resectability stage in patients with pancreatic ductal adenocarcinoma (PDAC), primarily to support radiologists in referral centers. Resectability of PDAC is determined by the degree of vascular involvement on computed tomography scans (CTs), whi... hiện toàn bộ
Average absorbed breast dose (2ABD): an easy radiation dose index for digital breast tomosynthesis
Springer Science and Business Media LLC - - 2020
Antonio Claudio Traino, Patrizio Barca, Rocco Lamastra, Raffaele M. Tucciariello, Chiara Sottocornola, Carolina Marini, Giacomo Aringhieri, Davide Caramella, Maria Evelina Fantacci
Right main pulmonary artery distensibility on dynamic ventilation CT and its association with respiratory function
Springer Science and Business Media LLC - - 2024
Tatsuya Oki, Yukihiro Nagatani, Shota Ishida, Masayuki Hashimoto, Yasuhiko Oshio, Jun Hanaoka, Ryo Uemura, Yoshiyuki Watanabe
Heartbeat-based cross-sectional area (CSA) changes in the right main pulmonary artery (MPA), which reflects its distensibility associated with pulmonary hypertension, can be measured using dynamic ventilation computed tomography (DVCT) in patients with and without chronic obstructive pulmonary disease (COPD) during respiratory dynamics. We investigated the relationship between MPA distensibility (... hiện toàn bộ
An MRI-guided HIFU-triggered wax-coated capsule for supertargeted drug release: a proof-of-concept study
Springer Science and Business Media LLC - Tập 3 - Trang 1-11 - 2019
Simon Matoori, Maurizio Roveri, Peter Tiefenboeck, Annatina Romagna, Olha Wuerthinger, Orpheus Kolokythas, Johannes M. Froehlich
Externally controlling and monitoring drug release at a desired time and location is currently lacking in the gastrointestinal tract. The aim of the study was to develop a thermoresponsive wax-coated capsule and to trigger its release upon applying a magnetic resonance imaging (MRI)-guided high-intensity focused ultrasound (HIFU) pulse. Capsules containing a lyophilised gadolinium-based contrast a... hiện toàn bộ
Radiological findings in ancient Egyptian canopic jars: comparing three standard clinical imaging modalities (x-rays, CT and MRI)
Springer Science and Business Media LLC - Tập 2 - Trang 1-9 - 2018
Patrick E. Eppenberger, Mislav Cavka, Michael E. Habicht, Francesco M. Galassi, Frank Rühli
The aim of our study was to evaluate the potential and the limitations of standard clinical imaging modalities for the examination of ancient Egyptian canopic jars and the mummified visceral organs (putatively) contained within them. A series of four ancient Egyptian canopic jars was imaged comparing the three standard clinical imaging modalities: x-rays, computed tomography (CT) and magnetic reso... hiện toàn bộ
PET/CT imaging for tumour response assessment to immunotherapy: current status and future directions
Springer Science and Business Media LLC - Tập 4 - Trang 1-13 - 2020
Marcus Unterrainer, Michael Ruzicka, Matthias P. Fabritius, Lena M. Mittlmeier, Michael Winkelmann, Johannes Rübenthaler, Matthias Brendel, Marion Subklewe, Michael von Bergwelt-Baildon, Jens Ricke, Wolfgang G. Kunz, Clemens C. Cyran
Recent immunotherapeutic approaches have evolved as powerful treatment options with high anti-tumour responses involving the patient’s own immune system. Passive immunotherapy applies agents that enhance existing anti-tumour responses, such as antibodies against immune checkpoints. Active immunotherapy uses agents that direct the immune system to attack tumour cells by targeting tumour antigens. A... hiện toàn bộ
Multiexponential T2 relaxometry of benign and malignant adipocytic tumours
Springer Science and Business Media LLC - Tập 4 - Trang 1-11 - 2020
Katerina Nikiforaki, Georgios S. Ioannidis, Eleni Lagoudaki, Georgios H. Manikis, Eelco de Bree, Apostolos Karantanas, Thomas G. Maris, Kostas Marias
We investigated a recently proposed multiexponential (Mexp) fitting method applied to T2 relaxometry magnetic resonance imaging (MRI) data of benign and malignant adipocytic tumours and healthy subcutaneous fat. We studied the T2 distributions of the different tissue types and calculated statistical metrics to differentiate benign and malignant tumours. Twenty-four patients with primary benign and... hiện toàn bộ
Thermal ablation with configurable shapes: a comprehensive, automated model for bespoke tumor treatment
Springer Science and Business Media LLC - Tập 7 Số 1
Iwan Paolucci, Milica Bulatović, Stefan Weber, Pascale Tinguely
Abstract Background Malignant tumors routinely present with irregular shapes and complex configurations. The lack of customization to individual tumor shapes and standardization of procedures limits the success and application of thermal ablation. Methods We introduced an automated treatment model consisting of (i) trajectory and ablation profile planning, (ii) ablation probe insertion, (iii) dyna... hiện toàn bộ
A machine learning approach for differentiating malignant from benign enhancing foci on breast MRI
Springer Science and Business Media LLC - Tập 4 - Trang 1-8 - 2020
Natascha C. D’Amico, Enzo Grossi, Giovanni Valbusa, Francesca Rigiroli, Bernardo Colombo, Massimo Buscema, Deborah Fazzini, Marco Ali, Ala Malasevschi, Gianpaolo Cornalba, Sergio Papa
Differentiate malignant from benign enhancing foci on breast magnetic resonance imaging (MRI) through radiomic signature. Forty-five enhancing foci in 45 patients were included in this retrospective study, with needle biopsy or imaging follow-up serving as a reference standard. There were 12 malignant and 33 benign lesions. Eight benign lesions confirmed by over 5-year negative follow-up and 15 ma... hiện toàn bộ
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