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Tuberculosis exposure, infection and disease in children: a systematic diagnostic approach
Springer Science and Business Media LLC - - 2016
Aboriginal and non-Aboriginal children in Western Australia carry different serotypes of pneumococci with different antimicrobial susceptibility profiles
Springer Science and Business Media LLC - Tập 8 - Trang 1-9 - 2016
Carriage of Streptococcus pneumoniae is considered a precursor to pneumococcal diseases including pneumonia. As part of the Kalgoorlie Otitis Media Research Project, we characterised pneumococci isolated from the nasopharynx of Western Australian Aboriginal and non-Aboriginal children. Between 1999 and 2005, 100 Aboriginal and 180 non-Aboriginal children were followed from birth to two years, with...... hiện toàn bộ
Economic burden of community-acquired pneumonia among elderly patients: a Japanese perspective
Springer Science and Business Media LLC - Tập 9 - Trang 1-10 - 2017
This study aimed to estimate the economic burden of community-acquired pneumonia (CAP) among elderly patients in Japan. In addition, the study evaluated the relationship between total treatment cost and CAP risk factors. An administrative database was searched for elderly patients (≥ 65 years old) who had pneumonia (ICD-10 code: J12–J18) and an antibiotic prescription between 1 June 2014 and 31 Ma...... hiện toàn bộ
Association of nasopharyngeal viruses and pathogenic bacteria in children and their parents with and without HIV
Springer Science and Business Media LLC - Tập 13 - Trang 1-10 - 2021
Bacteria and respiratory viruses co-occur in the nasopharynx, and their interactions may impact pathogenesis of invasive disease. Associations of viruses and bacteria in the nasopharynx may be affected by HIV. We conducted a nested case-control study from a larger cohort study of banked nasopharyngeal swabs from families with and without HIV in West Bengal India, to look at the association of viru...... hiện toàn bộ
Treatment of community-onset pneumonia in neutropenic cancer patients: β-lactam monotherapy versus combination antibiotic regimens
Springer Science and Business Media LLC - - 2019
Although β-lactam monotherapy may be sufficient in non-critically ill patients with community-acquired pneumonia, the value of combination antibiotic regimens in community-onset neutropenic pneumonia remains unclear. A retrospective cohort study was conducted to compare the effects of combination antibiotic regimens to those of β-lactam monotherapy in cancer patients with community-onset neutropen...... hiện toàn bộ
Innate immune responses in pneumonia
Springer Science and Business Media LLC - Tập 15 - Trang 1-26 - 2023
The lungs are an immunologically unique environment; they are exposed to innumerable pathogens and particulate matter daily. Appropriate clearance of pathogens and response to pollutants is required to prevent overwhelming infection, while preventing tissue damage and maintaining efficient gas exchange. Broadly, the innate immune system is the collection of immediate, intrinsic immune responses to...... hiện toàn bộ
Tuberculosis and pneumonia in HIV-infected children: an overview
Springer Science and Business Media LLC - - 2016
Pneumonia remains the most common cause of hospitalization and the most important cause of death in young children. In high human immunodeficiency virus (HIV)-burden settings, HIV-infected children carry a high burden of lower respiratory tract infection from common respiratory viruses, bacteria and Mycobacterium tuberculosis. In addition, Pneumocystis jirovecii and cytomegalovirus are important o...... hiện toàn bộ
A brief history of and future prospects for pneumococcal vaccination in Malaysia
Springer Science and Business Media LLC - Tập 15 - Trang 1-8 - 2023
Pneumococcal pneumonia remains a significant global public health issue. Malaysia has recently added the 10 valent pneumococcal conjugate vaccine to its national immunisation programme. Data on pneumococcal serotype epidemiology is vital for informing national vaccination policy. However, there remains a lack of representative population-based pneumococcal surveillance in Malaysia to help both the...... hiện toàn bộ
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