The Potential for PCR Based Testing to Improve Diagnosis and Treatment of SepsisSpringer Science and Business Media LLC - Tập 15 - Trang 372-379 - 2013
Ngan Lyle, John Boyd
Early and appropriate antibiotic use is critical for the treatment of sepsis. In practice, however, early antibiotic administration is hampered by diagnostic uncertainty with regard to both early diagnosis of disease and delayed or absent microbiological results. The diagnostic uncertainty often persists into the later stages of sepsis when clinical response to antibiotic treatment is assessed. Bl...... hiện toàn bộ
Sexually transmitted infections during pregnancySpringer Science and Business Media LLC - Tập 9 - Trang 125-133 - 2009
Hope L. Johnson, Emily J. Erbelding, Khalil G. Ghanem
Two million of the 15 million (13.3%) new cases of sexually transmitted infections (STIs) among persons 15 to 49 years old occur in pregnant women. Access to care and a provider’s ability to assess risk, screen, and treat STIs are critical factors in preventing adverse pregnancy outcomes. Significant variations in provider STI screening and treatment practices exist despite recommended guidelines....... hiện toàn bộ
The Current State and Future Prospects of Chronic Hepatitis C Virus Infection TreatmentSpringer Science and Business Media LLC - Tập 16 - Trang 1-10 - 2014
Christopher Moore, Josh Levitsky
Hepatitis C virus (HCV) infection is a significant cause of chronic liver disease with substantial long-term sequelae. Until very recently, therapies to cure HCV were hindered by high nonresponse rates and severe side effects. The first-generation protease inhibitor-containing regimens provided superior cure rates for many HCV-infected patients, although their side-effect profile proved to be quit...... hiện toàn bộ
Recent considerations in recurrent cellulitisSpringer Science and Business Media LLC - Tập 3 - Trang 461-465 - 2014
Larry M. Baddour
Cellulitis is a frequently diagnosed syndrome that causes considerable morbidity. For a subset of patients, recurrent bouts of infection impact their quality of life. Most cases are due to b-hemolytic streptococci or Staphylococcus aureus. Inclusion of interdigital space (toe web) or mucosal (anal) swab cultures may increase the ability to define pathogens among patients with lower extremity cellu...... hiện toàn bộ
Renal dysfunction in HIV-1-infected patientsSpringer Science and Business Media LLC - - 2002
Jeffrey B. Kopp
Improved therapy directed against opportunistic infection and HIV-1 itself has resulted in greatly enhanced patient survival in the past decade among patients infected with HIV-1. Since patients are living longer, HIV-1 infection is associated with a rising burden of kidney disease. Approximately 14% of black patients and 6% of white patients dying with HIV-1 infection in 1999 in the United States...... hiện toàn bộ
Vulvovaginal Candidiasis in PregnancySpringer Science and Business Media LLC - Tập 17 - Trang 1-6 - 2015
T. J. Aguin, J. D. Sobel
Prevalence studies indicate that Candida species colonize the vagina in at least 20 % of all women, rising to 30 % in pregnancy. Although, some studies concluded that pregnant women were more likely to have symptomatic vaginal infections caused by Candida, yet other studies found a high prevalence of asymptomatic infection only during pregnancy. Most episodes of symptomatic vulvovaginal candidiasi...... hiện toàn bộ
Why Activated Protein C Was Not Successful in Severe Sepsis and Septic Shock: Are We Still Tilting at Windmills?Springer Science and Business Media LLC - Tập 15 - Trang 407-412 - 2013
Peggy S. Lai, B. Taylor Thompson
Drotrecogin alpha activated (DAA), trade name Xigris, is a recombinant human protein C that has been the subject of controversy since 2001, when it became the first biologic agent approved for the treatment of severe sepsis and septic shock. The PROWESS trial showed a 6.1 % absolute reduction in 28-day mortality, although these findings were not replicated in later trials, ultimately leading to th...... hiện toàn bộ
Medical treatment of endocarditisSpringer Science and Business Media LLC - Tập 9 - Trang 271-282 - 2007
Elias Abrutyn, Christopher H. Cabell, Vance G. Fowler, Bruno Hoen, José M. Miro, Carlos A. Mestres, Daniel J. Sexton, G. Ralph Corey
Infective endocarditis (IE) remains a serious and deadly disease. The incidence, which varies by gender and on the presence of predisposing factors, has not decreased, due in part to the aging population with more healthcare exposures and predisposing risk factors such as prosthetic heart valves and intracardiac devices. The most important aspects of treatment in IE hinge upon early diagnosis, mic...... hiện toàn bộ