Springer Science and Business Media LLC

Công bố khoa học tiêu biểu

* Dữ liệu chỉ mang tính chất tham khảo

Sắp xếp:  
Association between red blood cell distribution width and macrovascular and microvascular complications in diabetes
Springer Science and Business Media LLC - Tập 55 - Trang 226-235 - 2011
N. Malandrino, W. C. Wu, T. H. Taveira, H. B. Whitlatch, R. J. Smith
Red blood cell distribution width (RDW) has been reported to be a risk marker of morbidity and mortality for cardiovascular disease in various study populations. However, no studies have investigated the relationship between RDW and diabetes complications. We therefore evaluated RDW as a marker of macrovascular and microvascular complications in a nationally representative sample of the adult diab...... hiện toàn bộ
DNA damage by the glycation products of glyceraldehyde 3-phosphate and lysine
Springer Science and Business Media LLC - Tập 37 - Trang 145-149 - 1994
E. A. Mullokandov, W. A. Franklin, M. Brownlee
In order to evaluate whether base modifications, apurinic/apyrimidinic site formation, strand breaks, or a combination of these lesions results from the interaction of glycation products with DNA, plasmid DNA was first reacted with these products, and then subjected to digestion with endonuclease III and endonuclease IV of Escherichia coli. Analysis of the differential effects of digestions with t...... hiện toàn bộ
Elevated nocturnal NEFA are an early signal for hyperinsulinaemic compensation during diet-induced insulin resistance in dogs
Springer Science and Business Media LLC - Tập 58 - Trang 2663-2670 - 2015
Josiane L. Broussard, Cathryn M. Kolka, Ana V. B. Castro, Isaac Asare Bediako, Rebecca L. Paszkiewicz, Edward W. Szczepaniak, Lidia S. Szczepaniak, Kristen L. Knutson, Stella P. Kim, Richard N. Bergman
A normal consequence of increased energy intake and insulin resistance is compensatory hyperinsulinaemia through increased insulin secretion and/or reduced insulin clearance. Failure of compensatory mechanisms plays a central role in the pathogenesis of type 2 diabetes mellitus; consequently, it is critical to identify in vivo signal(s) involved in hyperinsulinaemic compensation. We have previousl...... hiện toàn bộ
Announcements
Springer Science and Business Media LLC - Tập 31 - Trang 406-406 - 1988
Suppression of portal venous insulin concentration by epinephrine in the conscious monkey
Springer Science and Business Media LLC - Tập 5 - Trang 179-182 - 1969
R. E. Miller, J. S. Soeldner
Conscious male rhesus monkeys were given epinephrine bitartrate (1 μg/kg.min) through a catheter implanted in the right internal jugular vein. Blood samples were taken from the portal vein through another catheter before, during, and after a 15-minute-long jugular infusion. Sugar in the plasma rose during, and was still high 10 min after the infusion, while mean immunoreactive insulin decreased du...... hiện toàn bộ
Increased insulin dose requirement of long-acting insulin analogues in obese patients with type 2 diabetes
Springer Science and Business Media LLC - - 2009
Christoph Schmid, Pierre–Alexandre Krayenbühl, Peter Wiesli
Impact of age, age at diagnosis and duration of diabetes on the risk of macrovascular and microvascular complications and death in type 2 diabetes
Springer Science and Business Media LLC - Tập 57 - Trang 2465-2474 - 2014
Sophia Zoungas, Mark Woodward, Qiang Li, Mark E. Cooper, Pavel Hamet, Stephen Harrap, Simon Heller, Michel Marre, Anushka Patel, Neil Poulter, Bryan Williams, John Chalmers
Data are inconsistent regarding the associations between age, age at diagnosis of diabetes, diabetes duration and subsequent vascular complications. The associations between age (or age at diagnosis), diabetes duration and major macrovascular events, all-cause death and major microvascular events were examined in 11,140 patients with type 2 diabetes randomly allocated to intensive or standard gluc...... hiện toàn bộ
Can twin studies assess the genetic component in Type 2 (non-insulin-dependent) diabetes mellitus?
Springer Science and Business Media LLC - Tập 36 Số 5 - Trang 471-472 - 1993
David I. W. Phillips, Jaakko Tuomilehto
Saturated non-esterified fatty acids stimulate de novo diacylglycerol synthesis and protein kinase c activity in cultured aortic smooth muscle cells
Springer Science and Business Media LLC - Tập 44 - Trang 614-620 - 2001
H. Y. Yu, T. Inoguchi, M. Kakimoto, N. Nakashima, M. Imamura, T. Hashimoto, F. Umeda, H. Nawata
Aims/hypothesis. Insulin resistance is linked with a cluster of multiple risk factors and excessive acceleration of atherosclerosis. The underlying mechanism is not, however, fully understood. Methods. To determine the link between insulin resistance and altered vascular function, we focused on the effect of various non-esterified fatty acids on diacylglycerol-protein kinase C pat...... hiện toàn bộ
New insulins and other possible therapeutic approaches
Springer Science and Business Media LLC - Tập 40 - Trang B89-B93 - 1997
J. Johannesen, K. F. Petersen, M. Berger, C. Binder
Tổng số: 9,402   
  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • 10