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Association between red blood cell distribution width and macrovascular and microvascular complications in diabetes
Springer Science and Business Media LLC - Tập 55 - Trang 226-235 - 2011
N. Malandrino, W. C. Wu, T. H. Taveira, H. B. Whitlatch, R. J. Smith
Red blood cell distribution width (RDW) has been reported to be a risk marker of morbidity and mortality for cardiovascular disease in various study populations. However, no studies have investigated the relationship between RDW and diabetes complications. We therefore evaluated RDW as a marker of macrovascular and microvascular complications in a nationally representative sample of the adult diab...... hiện toàn bộ
DNA damage by the glycation products of glyceraldehyde 3-phosphate and lysine
Springer Science and Business Media LLC - Tập 37 - Trang 145-149 - 1994
E. A. Mullokandov, W. A. Franklin, M. Brownlee
In order to evaluate whether base modifications, apurinic/apyrimidinic site formation, strand breaks, or a combination of these lesions results from the interaction of glycation products with DNA, plasmid DNA was first reacted with these products, and then subjected to digestion with endonuclease III and endonuclease IV of Escherichia coli. Analysis of the differential effects of digestions with t...... hiện toàn bộ
Announcements
Springer Science and Business Media LLC - Tập 31 - Trang 406-406 - 1988
Suppression of portal venous insulin concentration by epinephrine in the conscious monkey
Springer Science and Business Media LLC - Tập 5 - Trang 179-182 - 1969
R. E. Miller, J. S. Soeldner
Conscious male rhesus monkeys were given epinephrine bitartrate (1 μg/kg.min) through a catheter implanted in the right internal jugular vein. Blood samples were taken from the portal vein through another catheter before, during, and after a 15-minute-long jugular infusion. Sugar in the plasma rose during, and was still high 10 min after the infusion, while mean immunoreactive insulin decreased du...... hiện toàn bộ
Increased insulin dose requirement of long-acting insulin analogues in obese patients with type 2 diabetes
Springer Science and Business Media LLC - - 2009
Christoph Schmid, Pierre–Alexandre Krayenbühl, Peter Wiesli
Impact of age, age at diagnosis and duration of diabetes on the risk of macrovascular and microvascular complications and death in type 2 diabetes
Springer Science and Business Media LLC - Tập 57 - Trang 2465-2474 - 2014
Sophia Zoungas, Mark Woodward, Qiang Li, Mark E. Cooper, Pavel Hamet, Stephen Harrap, Simon Heller, Michel Marre, Anushka Patel, Neil Poulter, Bryan Williams, John Chalmers
Data are inconsistent regarding the associations between age, age at diagnosis of diabetes, diabetes duration and subsequent vascular complications. The associations between age (or age at diagnosis), diabetes duration and major macrovascular events, all-cause death and major microvascular events were examined in 11,140 patients with type 2 diabetes randomly allocated to intensive or standard gluc...... hiện toàn bộ
Saturated non-esterified fatty acids stimulate de novo diacylglycerol synthesis and protein kinase c activity in cultured aortic smooth muscle cells
Springer Science and Business Media LLC - Tập 44 - Trang 614-620 - 2001
H. Y. Yu, T. Inoguchi, M. Kakimoto, N. Nakashima, M. Imamura, T. Hashimoto, F. Umeda, H. Nawata
Aims/hypothesis. Insulin resistance is linked with a cluster of multiple risk factors and excessive acceleration of atherosclerosis. The underlying mechanism is not, however, fully understood. Methods. To determine the link between insulin resistance and altered vascular function, we focused on the effect of various non-esterified fatty acids on diacylglycerol-protein kinase C pat...... hiện toàn bộ
Segmental demyelination in the distal peripheral nerves of chronically diabetic chinese hamsters
Springer Science and Business Media LLC - Tập 10 - Trang 541-548 - 1974
W. W. Schlaepfer, G. C. Gerritsen, W. E. Dulin
Distal tibial nerves of 14 chronically diabetic and 6 control Chinese hamsters were examined using ultrastructural and teased whole-mount methods. Glucosuria was present for varying intervals up to 976 days, while 10 hamsters manifested ketonuria for intervals up to 551 days. Myelin internodal ensheathment patterns were analyzed from whole-mount preparations. A normal proportional relationship exi...... hiện toàn bộ
Gastric and oesophageal emptying in patients with Type 2 (non-insulin-dependent) diabetes mellitus
Springer Science and Business Media LLC - Tập 32 - Trang 151-159 - 1989
M. Horowitz, P. E. Harding, A. F. Maddox, J. M. Wishart, L. M. A. Akkermans, B. E. Chatterton, D. J. C. Shearman
Gastric emptying of a digestible solid and liquid meal and oesophageal emptying of a solid bolus were measured with scintigraphic techniques in 20 randomly selected Type 2 (non-insulin-dependent) diabetic patients receiving oral hypoglycaemic therapy and 20 control subjects. In the diabetic patients, the relationships between oesophageal emptying, gastric emptying, gastrointestinal symptoms, auton...... hiện toàn bộ
Announcement
Springer Science and Business Media LLC - Tập 45 - Trang R9-R12 - 2014
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