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5′-Nucleotidase activity as a synaptic marker of parasagittal compartmentation in the mouse cerebellum
Springer Science and Business Media LLC - Tập 24 Số 11 - Trang 879-890 - 1995
In the molecular layer of the mouse cerebellum, the histochemical activity of the adenosine-producing ectoenzyme 5′-nucleotidase discloses a parasagittal pattern of alternating enzyme-rich and enzyme-poor bands. In the rat, 5′-nucleotidase activity transiently labels cerebellar synapses during postnatal development and shifts later on towards an exclusive glial location in the molecular layer. We ......
Dorsal thalamic connections of the ventral lateral geniculate nucleus of rats
Springer Science and Business Media LLC - Tập 29 - Trang 31-41 - 2000
In order to understand better the organisation of the ventral lateral geniculate nucleus of the ventral thalamus, this paper has examined the patterns of connections that this nucleus has with various nuclei of the dorsal thalamus in rats. Injections of biotinylated dextran or cholera toxin subunit B were made into the parafascicular, central lateral, posterior thalamic, medial dorsal, lateral dor......
Terminal sprouting in partially denervated muscle of the mouse: a scanning electron microscopic study
Springer Science and Business Media LLC - Tập 17 - Trang 563-571 - 1988
Terminal sprouting in the mouse gastrocnemius muscle was examined by scanning electron microscopy after partial denervation. After one of the two muscle nerves in the medial head was cut, terminal sprouts arose from the outer edge of the intact motor endplates and grew out onto a connective tissue layer on the muscle fibres. The sprouts were very slender along their length, although some had a var......
Immunocytochemical identification of GABA in astrocytes located in white matter after inhibition of GABA-transaminase with gamma-acetylenic GABA
Springer Science and Business Media LLC - Tập 20 - Trang 290-298 - 1991
Several lines of evidence suggest that astrocytes contribute to the uptake and degradation of the inhibitory neurotransmitter γ-aminobutyric acid (GABA). Recent immunohistochemical studies have shown that GABA-like immunoreactivity can be demonstrated in astrocytes in the grey matter of the rat's brainstem. The present study investigates whether GABA is also present in astrocytes located in the wh......
A giant nerve net with multi-effector synapses underlying epithelial adhesive strips in the mouth ofBeroë (Ctenophora)
Springer Science and Business Media LLC - Tập 24 - Trang 711-723 - 1995
We present ultrastructural evidence for the first known example of a giant nerve net in the phylum Ctenophora. The giant fibre system inBeroë underlies paired strips of adherent epithelial cells that run inside the lips. Interlocking actin-lined cell junctions between opposing adhesive strips keepBeroë's large mouth closed while the ctenophore searches for prey. The giant neurons, up to 6–8 μm in ......
The Nogo receptor, its ligands and axonal regeneration in the spinal cord; A review
Springer Science and Business Media LLC - Tập 31 - Trang 93-120 - 2002
At least three proteins present in CNS myelin, Nogo, MAG and OMgp are capable of causing growth cone collapse and inhibiting neurite outgrowth in vitro. Surprisingly, Nogo and OMgp are also strongly expressed by many neurons (including neocortical projection cells). Nogo expression is increased by some cells at the borders of CNS lesion sites and by cells in injured peripheral nerves, but Nogo and......
Survival, proliferation and morphological specialization of mouse Schwann cells in a serum-free, fully defined medium
Springer Science and Business Media LLC - Tập 9 - Trang 683-697 - 1980
Neonatal mouse dorsal root ganglionic (DRG) cell dissociates were cultured in a synthetic medium with horse serum or the serum-free supplement N1 (insulin, transferrin, progesterone, putrescine, selenium). Serum-supplemented cultures with added nerve growth factor (NGF) yielded neurons, small flat and spindle cells (Schwann) and large flat cells (fibroblastic elements). However, in serum-free, N1-......
Immunocytochemical localization of glycogen phosphorylase kinase in rat brain sections and in glial and neuronal primary cultures
Springer Science and Business Media LLC - - 1998
Summary. The physiological function of brain glycogen and the role of phosphorylase kinase as a regulatory enzyme in the cascade of reactions associated with glycogenolysis in the brain have not been fully elucidated. As a first step toward elucidating such a function, we studied the localization of phosphorylase kinase in glial and neuronal primary cell cultures, and in adult rat brain slices, us......
S-laminin and N-acetylgalactosamine located at the synaptic basal lamina of skeletal muscle are involved in synaptic recognition by growing neurites
Springer Science and Business Media LLC - Tập 24 - Trang 903-915 - 1995
The purpose of the work reported here is to identify molecular components of the synaptic basal lamina of skeletal muscle fibres which allow recognition of original synaptic sites by regenerating motor axons. We focused on s-larninin and components recognized by the lectinDolichos biflorus agglutinin previously shown to be specifically located at the synaptic basal lamina. We used a cryoculture bi......
Double myelination of axons in the sympathetic nervous system of the mouse. II. Mechanisms of formation
Springer Science and Business Media LLC - Tập 17 - Trang 263-276 - 1988
The phenomenon termed ‘double myelination’, present in sympathetic nerve of normal adult rats and mice, comprises regions of a myelinated axon which are concentrically ensheathed by additional (outer) myelinating Schwann cells. Evidence has been presented that in some instances the outer Schwann cell fails to make contact with an axon, yet its myelin sheath characteristically remains ultrastructur......
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