A nationwide survey of rapidly progressive glomerulonephritis in Japan: etiology, prognosis and treatment diversitySpringer Science and Business Media LLC - Tập 13 - Trang 633-650 - 2009
Akio Koyama, Kunihiro Yamagata, Hirofumi Makino, Yoshihiro Arimura, Takashi Wada, Kosaku Nitta, Hiroshi Nihei, Eri Muso, Yoshio Taguma, Hidekazu Shigematsu, Hideto Sakai, Yasuhiko Tomino, Seiichi Matsuo
The etiology, prevalence, and prognosis of rapidly progressive glomerulonephritis (RPGN) including renal vasculitis vary among races and periods. To improve the prognosis of Japanese RPGN patients, we conducted a nationwide survey of RPGN in the nephrology departments of 351 tertiary hospitals, and found 1772 patients with RPGN (Group A: diagnosed between 1989 and 1998, 884 cases; Group B: diagnos...... hiện toàn bộ
Searching for novel intercellular signal-transducing molecules in the kidney and their clinical applicationSpringer Science and Business Media LLC - Tập 14 - Trang 523-527 - 2010
Kiyoshi Mori, Masashi Mukoyama, Kazuwa Nakao
In this review, isolation and characterization of several kidney-derived molecules are described, namely carbonic anhydrase XIV, cysteine-rich protein 61, and kidney–liver-specific immunoglobulin-like protein. Features of neutrophil gelatinase-associated lipocalin (LCN2 or human neutrophil lipocalin) as a kidney differentiation inducer and renal injury biomarker and also as an iron-carrier protein...... hiện toàn bộ
Renal function evaluation in patients with cancer who were scheduled to receive carboplatin or S-1Springer Science and Business Media LLC - Tập 19 - Trang 1107-1113 - 2015
Kanako Shibata, Yoshinari Yasuda, Ryo Kobayashi, Yuichi Ando, Tomoya Shimokata, Hideki Kamiya, Mutsuharu Hayashi, Shoichi Maruyama, Seiichi Matsuo, Makoto Nakao, Teruo Tsuchiya, Hitomi Teramachi
Accurate glomerular filtration rate (GFR) evaluation is significant for drug dosing of carboplatin, anticancer drug excreted mainly from kidney. Serum cystatin-C (sCys-C) is a GFR marker with little affected by body muscle mass volume. And GFR equations based on serum creatinine (eGFRcreat) and sCys-C (eGFRcys) were developed; however, accuracy of eGFRcys has not been elucidated fully among patien...... hiện toàn bộ
Increase of 1,25 dihydroxyvitamin D in sarcoidosis patients with renal dysfunctionSpringer Science and Business Media LLC - - 2019
Naoya Toriu, Keiichi Sumida, Masahiko Oguro, Yōichi Ōshima, Hiroki Mizuno, Eiko Hasegawa, Tatsuya Suwabe, Manabu Kawada, Toshiharu Ueno, Noriko Hayami, Akinari Sekine, Rikako Hiramatsu, Masayuki Yamanouchi, Junichi Hoshino, Naoki Sawa, Kenmei Takaichi, Kenichi Ohashi, Keiichi Kinowaki, Takeshi Fujii, Ryosuke Date, Yoshifumi Ubara
Pathogenetic significance of aberrant glycosylation of IgA1 in IgA nephropathySpringer Science and Business Media LLC - Tập 12 - Trang 332-338 - 2008
Ichiei Narita, Fumitake Gejyo
IgA nephropathy (IgAN), the most common form of primary glomerulonephritis worldwide, is defined by predominant IgA1 deposits in the glomerular mesangium. Among abnormalities of the IgA immune system reported so far in IgAN, aberrant O-linked glycosylation in the hinge region of IgA1 is the most consistent finding. IgA1 molecules bearing abnormal glycosylation have been found in serum, in tonsilla...... hiện toàn bộ
Intra-body dynamics of d-serine reflects the origin of kidney diseasesSpringer Science and Business Media LLC - Tập 25 - Trang 893-901 - 2021
Hiroki Okushima, Yukimasa Iwata, Atsushi Hesaka, Eri Sugimori, Tatsuhiko Ikeda, Maiko Nakane, Masashi Mita, Terumasa Hayashi, Yoshitaka Isaka, Tomonori Kimura
d-Serine, present only in trace amounts in humans, is now recognized as a biomarker of chronic kidney disease (CKD). CKD is heterogeneous in its original kidney diseases, whose diagnoses require kidney biopsy. In this study, we examined whether the intra-body dynamics of d-serine, indexed by its blood and urinary levels, reflects the origin of kidney diseases. Patients with six kinds of kidney dis...... hiện toàn bộ