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Corticosteroid-Induced Osteoporosis
Springer Science and Business Media LLC - Tập 1 - Trang 271-279 - 2012
Ann Cranney, Jonathan D. Adachi
Corticosteroid-induced osteoporosis is the leading cause of secondary osteoporosis and a significant cause of morbidity in both men and women. Long-term use of even low-dose corticosteroids has been associated with increased risk of bone loss. Recent large randomized controlled trials have generated new knowledge on treatment strategies for patients with corticosteroid-induced osteoporosis. Howeve...... hiện toàn bộ
Diabetic Renal Disease in Patients with Type 2 Diabetes Mellitus
Springer Science and Business Media LLC - Tập 1 - Trang 3-11 - 2012
Carl Erik Mogensen
Over the last 35 years an increasing number of patients with type 2 diabetes mellitus have developed advanced renal disease and the need for dialysis. At present in the US, about 50% of the patients in dialysis units have type 2 diabetes mellitus. The explanation for the increase in the number of patients with type 2 diabetes mellitus in end-stage renal disease programs is not completely clear, bu...... hiện toàn bộ
Diabetic Ketoacidosis
Springer Science and Business Media LLC - Tập 2 - Trang 95-108 - 2012
Guillermo E. Umpierrez, Abbas E. Kitabchi
Diabetic ketoacidosis (DKA) is the most common hyperglycemic emergency in patients with diabetes mellitus. DKA most often occurs in patients with type 1 diabetes, but patients with type 2 diabetes are susceptible to DKA under stressful conditions, such as trauma, surgery, or infections. DKA is reported to be responsible for more than 100 000 hospital admissions per year in the US, and accounts for...... hiện toàn bộ
Strategies for the Management of Patients with Obesity
Springer Science and Business Media LLC - Tập 1 Số 1 - Trang 21-36 - 2002
Michael A. Hamilton
Opinion and Evidence for Treatments in Endocrine Disorders
Springer Science and Business Media LLC - Tập 4 - Trang 391-397 - 2012
The Effectiveness of Intensive Glycemic Control for the Prevention of Vascular Complications in Diabetes Mellitus
Springer Science and Business Media LLC - Tập 5 - Trang 273-286 - 2012
Abu R. Vasudevan, Alassia Burns, Vivian A. Fonseca
Obesity and type 2 diabetes mellitus have reached epidemic proportions in the US, and indeed, globally. While microvascular complications contribute to considerable morbidity, much of the excess mortality (around 70%) is due to macrovascular disease. Hyperglycemia has predictable toxic effects on multiple organs (‘glucotoxicity’) including the pancreas, where it impairs insulin secretion and insul...... hiện toàn bộ
Progress in Islet Transplantation in Patients with Type 1 Diabetes Mellitus
Springer Science and Business Media LLC - Tập 5 - Trang 147-158 - 2012
Wayne Truong, A. M. James Shapiro
More than 500 patients with type 1 diabetes mellitus have now received islet transplants at over 50 institutions worldwide in the past 5 years. Rates of insulin independence at 1 year with current protocols are impressive. However, inexorable decay of islet function over time indicates that there are many opportunities for improvement. Improved control of glycosylated hemoglobin and reduced risk o...... hiện toàn bộ
Treatment of Microalbuminuria in Patients with Type 2 Diabetes Mellitus
Springer Science and Business Media LLC - Tập 1 - Trang 163-173 - 2012
George Jerums, Richard J. Maclsaac
The incidence of type 2 diabetes mellitus is increasing world-wide, and is now one of the leading causes of end-stage renal disease in Western countries. Type 2 diabetes mellitus is also a major risk factor for cardiovascular events. Therefore, the early identification of patients at greatest risk, and the subsequent initiation of renal and cardiovascular protective treatments, are of the utmost i...... hiện toàn bộ
Managing Cutaneous Manifestations of Hyperandrogenic Disorders
Springer Science and Business Media LLC - Tập 1 - Trang 373-386 - 2012
Inka Wiegratz, Herbert Kuhl
Cutaneous manifestations of hyperandrogenic disorders (acne, seborrhea, hirsutism and androgenetic alopecia) can be caused by elevated levels of free testosterone or androgen precursors. In women with normal serum levels of testosterone or androgen precursors, enhanced local conversion to testosterone, or to the more potent androgen dihydrotestosterone, may lead to increased androgen activity in t...... hiện toàn bộ
The Role of Thiazolidinediones in the Treatment of Patients with Type 2 Diabetes Mellitus
Springer Science and Business Media LLC - Tập 1 - Trang 13-20 - 2012
Arshag D. Mooradian, Joe Chehade, Jerome E. Thurman
Diabetes mellitus is a significant and growing health concern worldwide. Unfortunately, type 2 diabetes mellitus is generally under-managed, and this may explain the increasing prevalence of diabetic complications throughout the world. The introduction of newer classes of antihyperglycemic agents should enhance the ability of clinicians to achieve optimal blood glucose control. One recent addition...... hiện toàn bộ
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