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The trials and tribulations of accessing data from routine sources
Springer Science and Business Media LLC - Tập 16 - Trang 1-1 - 2015
Graham Powell, Tony Marson, Dyfrig Hughes, Paula Williamson, Catrin Tudur-Smith
Performance of model-based vs. permutation tests in the HEALing (Helping to End Addiction Long-termSM) Communities Study, a covariate-constrained cluster randomized trial
Springer Science and Business Media LLC - Tập 23 - Trang 1-10 - 2022
Xiaoyu Tang, Timothy Heeren, Philip M. Westgate, Daniel J. Feaster, Soledad A. Fernandez, Nathan Vandergrift, Debbie M. Cheng
The HEALing (Helping to End Addiction Long-termSM) Communities Study (HCS) is a multi-site parallel group cluster randomized wait-list comparison trial designed to evaluate the effect of the Communities That Heal (CTH) intervention compared to usual care on opioid overdose deaths. Covariate-constrained randomization (CCR) was applied to balance the community-level baseline covariates in the HCS. T...... hiện toàn bộ
Does an 8-week home-based exercise program affect physical capacity, quality of life, sick leave, and use of psychotropic drugs in patients with pulmonary embolism? Study protocol for a multicenter randomized clinical trial
Springer Science and Business Media LLC - Tập 18 Số 1 - Trang 1-8 - 2017
Rolving, Nanna, Brocki, Barbara C., Mikkelsen, Hanne R., Ravn, Pernille, Bloch-Nielsen, Jannie Rhod, Frost, Lars
The existing evidence base in pulmonary embolism (PE) is primarily focused on diagnostic methods, medical treatment, and prognosis. Only a few studies have investigated how everyday life is affected by PE, although many patients are negatively affected both physically and emotionally after hospital discharge. Currently, no documented rehabilitation options are available for these patients. We aim ...... hiện toàn bộ
Public engagement in outcomes development - three degrees of separation
Springer Science and Business Media LLC - Tập 16 - Trang 1-1 - 2015
Sally Crowe, Sandra Regan, Ann Daly
Effects of neuromuscular training on pain intensity and self-reported functionality for patellofemoral pain syndrome in runners: study protocol for a randomized controlled clinical trial
Springer Science and Business Media LLC - Tập 20 Số 1 - 2019
Hongpu Hu, Yili Zheng, Xiaochen Liu, Di Gong, Changcheng Chen, Yi-Zu Wang, Meng‐Si Peng, Wu Bao, Juan Wang, Ge Song, Juan Zhang, Jiamei Guo, Yulin Dong, Xueqiang Wang
Pre-exposure prophylaxis with hydroxychloroquine for high-risk healthcare workers during the COVID-19 pandemic: A structured summary of a study protocol for a multicentre, double-blind randomized controlled trial
Springer Science and Business Media LLC - Tập 21 Số 1 - 2020
Berta Grau-Pujol, Daniel Camprubí, Helena Martí-Soler, Marc Fernández-Pardos, Caterina Guinovart, José Muñóz
Abstract Objectives The aim of this study is to assess the efficacy of the use of pre-exposure prophylaxis (PrEP) with hydroxychloroquine against placebo in healthcare workers with high risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in reducing their risk of coronavirus disease 2019 (COVID-19) disea...... hiện toàn bộ
Protocol for the Proactive Or Reactive Telephone Smoking CeSsation Support (PORTSSS) trial
Springer Science and Business Media LLC - Tập 10 - Trang 1-12 - 2009
Tim Coleman, Andy McEwen, Linda Bauld, Janet Ferguson, Paula Lorgelly, Sarah Lewis
Telephone quit lines are accessible to many smokers and are used to engage motivated smokers to make quit attempts. Smoking cessation counselling provided via telephone can either be reactive (i.e. primarily involving the provision of evidence-based information), or proactive (i.e. primarily involving repeated, sequenced calls from and interaction with trained cessation counsellors). Some studies ...... hiện toàn bộ
Equipoise in action: a qualitative investigation across six pragmatic randomised controlled trials (RCTs)
Springer Science and Business Media LLC - Tập 16 - Trang 1-1 - 2015
Leila Rooshenas, Daisy Townsend, Julia Wade, Caroline Wilson, Jane Blazeby, Jenny Donovan
The impact of Mediterranean diet on coronary plaque vulnerability, microvascular function, inflammation and microbiome after an acute coronary syndrome: study protocol for the MEDIMACS randomized, controlled, mechanistic clinical trial
Springer Science and Business Media LLC - Tập 22 Số 1 - 2021
Ana Fernández, Javier Bermejo, Raquel Yotti, Miguel Ángel Martínez‐González, Álex Mira, Uri Gophna, Roger Karlsson, Reem Al-Daccak, Irene Martín de Miguel, Enrique Gutiérrez‐Ibañes, Dominique Charron, Francisco Fernández‐Avilés
Abstract Background Primary prevention trials have demonstrated that the traditional Mediterranean diet is associated with a reduction in cardiovascular mortality and morbidity. However, this benefit has not been proven for secondary prevention after an acute coronary syndrome (ACS). We hypothesized...... hiện toàn bộ
Evaluation of a home-based transcranial direct current stimulation (tDCS) treatment device for chronic pain: study protocol for a randomised controlled trial
Springer Science and Business Media LLC - Tập 16 - Trang 1-6 - 2015
Francis O’Neill, Paul Sacco, Turo Nurmikko
Stimulation of the primary motor cortex (M1) has been shown to reduce the pain of neuropathy in multiple studies. There are several methods of stimulation both invasive and non-invasive. Recent work by this laboratory has seen that 40% of a sample of chronic neuropathic pain patients responded positively to non-invasive repetitive transcranial magnetic stimulation (rTMS) to the motor cortex with a...... hiện toàn bộ
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