Cornerstone program for transition-age youth with serious mental illness: study protocol for a randomized controlled trialSpringer Science and Business Media LLC - Tập 17 - Trang 1-13 - 2016
Michelle R. Munson, Andrea Cole, Victoria Stanhope, Steven C. Marcus, Mary McKay, James Jaccard, Shelly Ben-David
Transition-age youth have elevated rates of mental disorders, and they often do not receive services. This is a serious public health concern, as mental health conditions persist into adulthood. Continuing to engage this population has been a pervasive challenge for the mental health care system worldwide. Few mental health interventions have been developed for transition-age youth, and even fewer...... hiện toàn bộ
Stopping guidelines for an effectiveness trial: what should the protocol specify?Springer Science and Business Media LLC - Tập 17 - Trang 1-4 - 2016
Jon E. Tyson, Claudia Pedroza, Dennis Wallace, Carl D’Angio, Edward F. Bell, Abhik Das
Despite long-standing problems in decisions to stop clinical trials, stopping guidelines are often vague or unspecified in the trial protocol. Clear, well-conceived guidelines are especially important to assist the data monitoring committees for effectiveness trials. To specify better stopping guidelines in the protocol for such trials, the clinical investigators and trial statistician should care...... hiện toàn bộ
Gene therapy for lipid disordersSpringer Science and Business Media LLC - Tập 1 - Trang 1-8 - 2000
Masa-aki Kawashiri, Daniel J Rader
Lipid disorders are associated with atherosclerotic vascular disease, and therapy is associated with a substantial reduction in cardiovascular events. Current approaches to the treatment of lipid disorders are ineffective in a substantial number of patients. New therapies for refractory hypercholesterolemia, severe hypertriglyceridemia, and low levels of high-density lipoprotein cholesterol are ne...... hiện toàn bộ
Activity tracker-based intervention to increase physical activity in patients with type 2 diabetes and healthy individuals: study protocol for a randomized controlled trialSpringer Science and Business Media LLC - - 2022
Mareike Mähs, Jana Sabrina Pithan, I. Bergmann, Lars Gabrys, Johanna Graf, A. Hölzemann, Kristof Van Laerhoven, S. Otto-Hagemann, M. L. Popescu, L. Schwermann, Benjamin Wenz, I. Pahmeier, Andrea Teti
Abstract
Background
One relevant strategy to prevent the onset and progression of type 2 diabetes mellitus (T2DM) focuses on increasing physical activity. The use of activity trackers by patients could enable objective measurement of their regular physical activity in daily life and promote physical...... hiện toàn bộ