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The association of nonalcoholic fatty liver disease with bone mineral density in type 2 diabetes
Springer Science and Business Media LLC - Tập 27 - Trang 1-7 - 2022
Juan Du, Yan Ma, Hongmei Lang, Changquan Huang, Xingping Zhang
We examined the association between nonalcoholic fatty liver disease and lumbar spine bone mineral density in individuals with and without type 2 diabetes. The lumbar BMD of 1088 subjects was measured using dual-energy X-ray absorptiometry (DXA). Liver fat content was quantified via B-mode ultrasound. Multivariable linear regression was used to study the association between NAFLD and lumbar BMD in...... hiện toàn bộ
Management strategy for hematological malignancy patients with acute respiratory failure
Springer Science and Business Media LLC - Tập 26 - Trang 1-8 - 2021
Li Jiang, Qunfang Wan, Hongbing Ma
Acute respiratory failure (ARF) is still the major cause of intensive care unit (ICU) admission for hematological malignancy (HM) patients although the advance in hematology and supportive care has greatly improved the prognosis. Clinicians have to make decisions whether the HM patients with ARF should be sent to ICU and which ventilation support should be administered. Based on the reported inves...... hiện toàn bộ
Obesity is associated with increased severity of disease in COVID-19 pneumonia: a systematic review and meta-analysis
Springer Science and Business Media LLC - Tập 25 - Trang 1-15 - 2020
Yanan Chu, Jinxiu Yang, Jiaran Shi, Pingping Zhang, Xingxiang Wang
Obesity has been widely reported to be associated with the disease progression of coronavirus disease 2019 (COVID-19); however, some studies have reported different findings. We conducted a systematic review and meta-analysis to investigate the association between obesity and poor outcomes in patients with COVID-19 pneumonia. A systematic review and meta-analysis of studies from the PubMed, Embase...... hiện toàn bộ
Can radiologic parameters used to detect cervical spinal instability be used in patients with ankylosing spondylitis?
Springer Science and Business Media LLC - Tập 28 - Trang 1-7 - 2023
Henrik Teuber, Sascha Halvachizadeh, Melvin Muthirakalayil, Luxu Yin, Harry Eisenkrein, Frank Hildebrand, Philipp Kobbe, Kai Sprengel, Ladislav Mica, Hatem Alkadhi, Hans-Christoph Pape, Roman Pfeifer
Cervical spinal instability can be difficult to detect in the shock room setting even with the utilization of computed tomography (CT) scans. This may be especially true in patients with cervical degenerative disease, such as ankylosing spondylitis (AS). The purpose of this study was to investigate the influence AS has on various radiologic parameters used to detect traumatic and degenerative inst...... hiện toàn bộ
Update on microbicide research and development-seeking new HIV prevention tools for women
Springer Science and Business Media LLC - Tập 16 - Trang 1-6 - 2011
T. Mertenskoetter, P. E. Kaptur
Women and girls are especially vulnerable to HIV infection in sub-Saharan Africa, and in some of those countries, prevalence among young women can be up to 3 times higher than among men of the same age. Effective HIV prevention options for women are clearly needed in this setting. Several ARV-based vaginal microbicides are currently in development for prevention of HIV transmission to women and ar...... hiện toàn bộ
Metastasis of breast cancer to bones alters the tumor immune microenvironment
Springer Science and Business Media LLC - Tập 28 - Trang 1-9 - 2023
Xue Chao, Ying Zhang, Chengyou Zheng, Qitao Huang, Jiabin Lu, Emilia M. Pulver, Julia Houthuijzen, Stefan Hutten, Rongzhen Luo, Jiehua He, Peng Sun
Bone is one of the most frequent sites for breast cancer metastasis. Breast cancer bone metastasis (BCBM) leads to skeletal morbidities including pain, fractures, and spinal compression, all of which severely impact quality of life. Immunotherapy is a promising therapy for patients with advanced cancer, but whether it may provide benefit to metastatic bone cancer is currently unknown. Thus, a bett...... hiện toàn bộ
Calcium oxalate crystal-induced secretome derived from proximal tubular cells, not that from distal tubular cells, induces renal fibroblast activation
Springer Science and Business Media LLC - Tập 28 Số 1
Chadanat Noonin, Tanakorn Itsaranawet, Visith Thongboonkerd
Abstract Background Kidney stone disease (KSD) is commonly accompanied with renal fibrosis, characterized by accumulation and reorganization of extracellular matrix (ECM). During fibrogenesis, resident renal fibroblasts are activated to become myofibroblasts that actively produce ECM. However, such ...... hiện toàn bộ
Observation of the influences of diosgenin on aging ovarian reserve and function in a mouse model
Springer Science and Business Media LLC - Tập 22 - Trang 1-7 - 2017
Mingjie Shen, Cong Qi, Yan-Ping Kuang, Yang Yang, Qi-Feng Lyu, Hui Long, Zhi-Guang Yan, Ying-Yu Lu
The aim of this study was to investigate the impact of diosgenin, an important monomer of sapogenins in yams, on ovarian reserve in a natural aging mice model. This randomized controlled trial included 60 9-month-old C57 naturally aging female mice. Twenty-one mice were assigned to the dio group and were fed a single dose of diosgenin (200 mg/kg/day) suspended in 0.3% CMC. Twenty mice were assigne...... hiện toàn bộ
The impact of early pregnancy metabolic disorders on pregnancy outcome and the specific mechanism
Springer Science and Business Media LLC - Tập 28 Số 1
Xiaoqi Zhu, Zhanfeng Deng, Fangfang Dai, Hua Liu, Yanxiang Cheng
AbstractMiscarriage is the most common complication of pregnancy. The most common causes of early miscarriage are chromosomal abnormalities of the embryo, maternal endocrine abnormalities, organ malformations, and abnormal immune factors. Late miscarriages are mostly caused by factors such as cervical insufficiency. However, the causes of 50% of miscarriages remain...... hiện toàn bộ
The cause and effect of gut microbiota in development of inflammatory disorders of the breast
Springer Science and Business Media LLC - Tập 28 Số 1
Yufei Gu, Ming‐Chih Hou, Junhao Chu, Li Wan, Ming Yang, Jiacheng Shen, Minghui Ji
Abstract Background Inflammatory disorders of the breast (IDB) damages the interests of women and children and hinders the progress of global health seriously. Several studies had offered clues between gut microbiota (GM) and inflammatory disorders of the breast (IDB). The gut–mammary gland axis als...... hiện toàn bộ
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