The association of nonalcoholic fatty liver disease with bone mineral density in type 2 diabetesSpringer Science and Business Media LLC - Tập 27 - Trang 1-7 - 2022
Juan Du, Yan Ma, Hongmei Lang, Changquan Huang, Xingping Zhang
We examined the association between nonalcoholic fatty liver disease and lumbar spine bone mineral density in individuals with and without type 2 diabetes. The lumbar BMD of 1088 subjects was measured using dual-energy X-ray absorptiometry (DXA). Liver fat content was quantified via B-mode ultrasound. Multivariable linear regression was used to study the association between NAFLD and lumbar BMD in...... hiện toàn bộ
Visualization of breast cancer-related protein synthesis from the perspective of bibliometric analysisSpringer Science and Business Media LLC -
Jie Xu, Chengdong Yu, X. Zeng, Weifeng Tang, Siyi Xu, Lei Tang, Yanxiao Huang, Zhi‐Jun Sun, Tenghua Yu
AbstractBreast cancer, as a daunting global health threat, has driven an exponential growth in related research activity in recent decades. An area of research of paramount importance is protein synthesis, and the analysis of specific proteins inextricably linked to breast cancer. In this article, we undertake a bibliometric analysis of the literature on breast can...... hiện toàn bộ
Management strategy for hematological malignancy patients with acute respiratory failureSpringer Science and Business Media LLC - Tập 26 - Trang 1-8 - 2021
Li Jiang, Qunfang Wan, Hongbing Ma
Acute respiratory failure (ARF) is still the major cause of intensive care unit (ICU) admission for hematological malignancy (HM) patients although the advance in hematology and supportive care has greatly improved the prognosis. Clinicians have to make decisions whether the HM patients with ARF should be sent to ICU and which ventilation support should be administered. Based on the reported inves...... hiện toàn bộ
A novel stop-gain pathogenic variant in FLT4 and a nonsynonymous pathogenic variant in PTPN11 associated with congenital heart defectsSpringer Science and Business Media LLC - Tập 27 Số 1
Avisa Tabib, Taravat Talebi, Serwa Ghasemi, Maryam Pourirahim, Niloofar Naderi, Majid Maleki, Samira Kalayinia
Abstract
Background
Congenital heart defects (CHDs) are the most common congenital malformations, including structural malformations in the heart and great vessels. CHD complications such as low birth weight, prematurity, pregnancy termination, mortality, and morbidity depend on the type of defect.<...... hiện toàn bộ
Obesity is associated with increased severity of disease in COVID-19 pneumonia: a systematic review and meta-analysisSpringer Science and Business Media LLC - Tập 25 - Trang 1-15 - 2020
Yanan Chu, Jinxiu Yang, Jiaran Shi, Pingping Zhang, Xingxiang Wang
Obesity has been widely reported to be associated with the disease progression of coronavirus disease 2019 (COVID-19); however, some studies have reported different findings. We conducted a systematic review and meta-analysis to investigate the association between obesity and poor outcomes in patients with COVID-19 pneumonia. A systematic review and meta-analysis of studies from the PubMed, Embase...... hiện toàn bộ
Can radiologic parameters used to detect cervical spinal instability be used in patients with ankylosing spondylitis?Springer Science and Business Media LLC - Tập 28 - Trang 1-7 - 2023
Henrik Teuber, Sascha Halvachizadeh, Melvin Muthirakalayil, Luxu Yin, Harry Eisenkrein, Frank Hildebrand, Philipp Kobbe, Kai Sprengel, Ladislav Mica, Hatem Alkadhi, Hans-Christoph Pape, Roman Pfeifer
Cervical spinal instability can be difficult to detect in the shock room setting even with the utilization of computed tomography (CT) scans. This may be especially true in patients with cervical degenerative disease, such as ankylosing spondylitis (AS). The purpose of this study was to investigate the influence AS has on various radiologic parameters used to detect traumatic and degenerative inst...... hiện toàn bộ
Polymorphisms and mutations of ACE2 and TMPRSS2 genes are associated with COVID-19: a systematic reviewSpringer Science and Business Media LLC - Tập 27 - Trang 1-10 - 2022
Jingwei Li, Yali Wang, Yong Liu, Ziqu Zhang, Yuyun Zhai, Yan Dai, Zijian Wu, Xiang Nie, Lunfei Du
To determine the effect of polymorphisms and mutations in angiotensin-converting enzyme 2 (ACE2) and Type 2 transmembrane serine proteases (TMPRSS2) genes on susceptibility to corona virus disease 2019 (COVID-19) and patient prognosis. From December 2019 to the current time, an outbreak of epidemic of COVID-19, characterized by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has occur...... hiện toàn bộ
Update on microbicide research and development-seeking new HIV prevention tools for womenSpringer Science and Business Media LLC - Tập 16 - Trang 1-6 - 2011
T. Mertenskoetter, P. E. Kaptur
Women and girls are especially vulnerable to HIV infection in sub-Saharan Africa, and in some of those countries, prevalence among young women can be up to 3 times higher than among men of the same age. Effective HIV prevention options for women are clearly needed in this setting. Several ARV-based vaginal microbicides are currently in development for prevention of HIV transmission to women and ar...... hiện toàn bộ
Metastasis of breast cancer to bones alters the tumor immune microenvironmentSpringer Science and Business Media LLC - Tập 28 - Trang 1-9 - 2023
Xue Chao, Ying Zhang, Chengyou Zheng, Qitao Huang, Jiabin Lu, Emilia M. Pulver, Julia Houthuijzen, Stefan Hutten, Rongzhen Luo, Jiehua He, Peng Sun
Bone is one of the most frequent sites for breast cancer metastasis. Breast cancer bone metastasis (BCBM) leads to skeletal morbidities including pain, fractures, and spinal compression, all of which severely impact quality of life. Immunotherapy is a promising therapy for patients with advanced cancer, but whether it may provide benefit to metastatic bone cancer is currently unknown. Thus, a bett...... hiện toàn bộ