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Transplantation after blunt trauma to the liver: a valuable option or just a "waste of organs"?
Springer Science and Business Media LLC - Tập 15 - Trang 169-173 - 2010
Liver injury due to trauma is a rare indication for transplantation. The main indications in such cases were uncontrollable bleeding and insufficient hepatic function. Because of poor results, liver transplantation in these patients is occasionally described as "waste of organs", however based on insufficient data. This study aims to report our experience and to critically question the indication ...... hiện toàn bộ
Migration pattern of cementless press fit cups in the presence of stabilizing screws in total hip arthroplasty
Springer Science and Business Media LLC - Tập 16 Số 3 - Trang 127-132 - 2011
The aim of this study was to evaluate the initial acetabular implant stability and late acetabular implant migration in press fit cups combined with screw fixation of the acetabular component in order to answer the question whether screws are necessary for the fixation of the acetabular component in cementless primary total hip arthroplasty. One hundred and seven hips were available for follow-up ...... hiện toàn bộ
Repurposing approved non-oncology drugs for cancer therapy: a comprehensive review of mechanisms, efficacy, and clinical prospects
Springer Science and Business Media LLC - Tập 28 - Trang 1-35 - 2023
Cancer poses a significant global health challenge, with predictions of increasing prevalence in the coming years due to limited prevention, late diagnosis, and inadequate success with current therapies. In addition, the high cost of new anti-cancer drugs creates barriers in meeting the medical needs of cancer patients, especially in developing countries. The lengthy and costly process of developi...... hiện toàn bộ
The causal relationship between white blood cell counts and hepatocellular carcinoma: a Mendelian randomization study
Springer Science and Business Media LLC - - 2022
Most of hepatocellular carcinoma (HCC) arises on the background of chronic inflammation. The presence of infiltrating inflammatory cells is associated with tumour initiation, progression and clinical response to treatment. The influence of white blood cell (WBC) subtype counts on HCC progression remains unclear. In this study, we performed a Mendelian randomization (MR) study with the validation o...... hiện toàn bộ
ENT characteristics and therapeutic results in multisystemic disorders of mitochondrial encephalomyopathy
Springer Science and Business Media LLC - Tập 27 - Trang 1-12 - 2022
Here we report the evaluation of the frequency of subjective and objective otolaryngologic findings and therapeutic results in 32 patients with mitochondrial encephalomyopathy (MEM) from September 2001 to June 2021. Our analysis included studying the patients’ family histories, the clinical manifestations of MEM, and the therapeutic effects of treatments. The patients’ ages ranged from 2 to 77 yea...... hiện toàn bộ
Right atrial myxoma as the first manifestation of granulomatosis with polyangiitis, and a possible association with vascular endothelial growth factor (VEGF) and interleukin 6 (IL-6): a case report and review of the literature
Springer Science and Business Media LLC - Tập 27 - Trang 1-4 - 2022
Granulomatosis with polyangiitis and myxomas are rare conditions previously described to co-exist. Cardiac masses are often presumed to be myxomas rather than lesions of granulomatosis with polyangiitis. We present a review of the symptoms for the two diagnoses along with the first verified case. Two possible risk factors for developing myxomas (VEGF and IL-6) are explored and discussed.
Ubiquitin-conjugating enzyme E2C (UBE2C) is a prognostic indicator for cholangiocarcinoma
Springer Science and Business Media LLC - Tập 28 - Trang 1-12 - 2023
Cholangiocarcinoma is the most common malignant bile duct tumor in Southeast Asia. The special location of cholangiocarcinoma leads to it being difficult to diagnose. Currently, the progress in clinical prognosis outcomes remains abysmal owing to the lack of definitive diagnostic criteria. Therefore, uncovering the potential markers for cholangiocarcinoma is a pressing issue. Ubiquitin-conjugating...... hiện toàn bộ
Correction: Evaluating safety risks of whole-body cryotherapy/cryostimulation (WBC): a scoping review from an international consortium
Springer Science and Business Media LLC - - 2024
Maintenance electroconvulsive therapy for comorbid pharmacotherapy-refractory obsessive-compulsive and schizoaffective disorder
Springer Science and Business Media LLC - Tập 14 - Trang 367-368 - 2009
There is a high comorbidity of schizophrenia and obsessive-compulsory disorder (OCD) associated with more severe symptoms. Standard pharmacotherapy achieve symptom improvement in approximately 60% only. We report about a 48-old women treated for depression which developed successively psychotic symptoms (ideas of reference, psychotic worries), negative symptoms (blunted affect, impoverished thinki...... hiện toàn bộ
Threshold-modifying effect of the systemic inflammatory response index on kidney function decline in hypertensive patients
Springer Science and Business Media LLC - - 2024
Chronic kidney disease (decreased kidney function) is common in hypertensive patients. The SIRI is a novel immune biomarker. We investigated the correlation between the SIRI and kidney function in hypertensive patients. The present study analyzed data from participants who suffered from hypertension in the NHANES from 2009 to 2018. Multivariate regression analysis and subgroup analysis were used t...... hiện toàn bộ
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