Springer Science and Business Media LLC

Công bố khoa học tiêu biểu

* Dữ liệu chỉ mang tính chất tham khảo

Sắp xếp:  
Preclinical animal models of COPD
Springer Science and Business Media LLC - Tập 10 - Trang 1-1 - 2013
Ross Vlahos
Characterizing heterogeneity in the response of synovial mesenchymal progenitor cells to synovial macrophages in normal individuals and patients with osteoarthritis
Springer Science and Business Media LLC - Tập 13 - Trang 1-11 - 2016
Akash Fichadiya, Karri L Bertram, Guomin Ren, Robin M Yates, Roman J Krawetz
Resident macrophages in OA synovial tissue contribute to synovitis through pro-inflammatory mediators driving cartilage loss. What remains unknown is how these macrophages interact with synovial mesenchymal progenitor cells (sMPCs) in the joint. sMPCs have the potential to undergo chondrogenesis, but for yet unknown reasons, this ability is decreased in OA patients. In this study, we sought to ide...... hiện toàn bộ
TGF-β gene polimorphisms as risk factors for asthma control among clinic patients
Springer Science and Business Media LLC - Tập 18 - Trang 1-12 - 2021
Panek Michał, Stawiski Konrad, Kuna Piotr
TGF-β and its receptors play a crucial role in asthma pathogenesis, bronchial hyperreactivity, and bronchial remodeling. Expression of isoforms 1–3 of TGFβ cytokine is influenced by tagging polymorphisms in the TGFβ1, TGFβ2 and TGFβ3 gene, and these SNPs may be associated with the risk of asthma development and severity as well as with other diseases. Polymorphic forms of TGF-β1, TGF-β2 and TGF-β3...... hiện toàn bộ
Does carbon monoxide treatment alter cytokine levels after endotoxin infusion in pigs? A randomized controlled study
Springer Science and Business Media LLC - Tập 5 - Trang 1-8 - 2008
Anna-Maja Åberg, Pernilla Abrahamsson, Göran Johansson, Michael Haney, Ola Winsö, Jan Erik Larsson
Carbon monoxide (CO) has recently been suggested to have anti-inflammatory properties, but data seem to be contradictory and species-specific. Thus, in studies on macrophages and mice, pretreatment with CO attenuated the inflammatory response after endotoxin exposure. On the other hand, human studies showed no effect of CO on the inflammatory response. Anti-inflammatory efficacy of CO has been sho...... hiện toàn bộ
Relationship between vitamin D status and the inflammatory state in patients with chronic spontaneous urticaria
Springer Science and Business Media LLC - Tập 11 - Trang 1-5 - 2014
Alicja Grzanka, Edyta Machura, Bogdan Mazur, Maciej Misiolek, Jerzy Jochem, Jacek Kasperski, Alicja Kasperska-Zajac
Chronic spontaneous urticaria (CSU) is an immune-inflammatory disease, characterized by acute phase response (APR) and immune activation. There has been increasing evidence showing that vitamin D deficiency/insufficiency is associated with increased incidence and/or severity of immune-inflammatory disorders. To assess relationship between vitamin D status and C-reactive protein (CRP), a nonspecifi...... hiện toàn bộ
Nurr1 dependent regulation of pro-inflammatory mediators in immortalised synovial fibroblasts
Springer Science and Business Media LLC - Tập 2 Số 1 - Trang 1-8 - 2005
Davies, Mark R, Harding, Christine J, Raines, Stephanie, Tolley, Kurt, Parker, Andrew E, Downey-Jones, Mark, Needham, Maurice RC
Nurr1 is an orphan member of the nuclear receptor superfamily; these orphan receptors are a group for which a ligand has yet to be identified. Nurr1 has been shown to regulate the expression of a small number of genes as a monomeric, constitutively active receptor. These Nurr1 regulated genes are primarily associated with dopamine cell maturation and survival. However, previous reports have shown ...... hiện toàn bộ
Thrombin increases inflammatory cytokine and angiogenic growth factor secretion in human adipose cells in vitro
Springer Science and Business Media LLC - Tập 6 - Trang 1-10 - 2009
Jennifer L Strande, Shane A Phillips
Abdominal obesity is associated with pro-thrombotic and inflammatory states. Therefore, the purpose of this study was to examine the expression of thrombin receptors (PAR1 and PAR4) human adipose tissue and whether thrombin stimulates an inflammatory cytokine and growth factor profile in human adipose tissue. Human adipose tissue, isolated preadipocytes and differentiated adipocytes were used in t...... hiện toàn bộ
A comparative study of blood endotoxin detection in haemodialysis patients
Springer Science and Business Media LLC - Tập 13 - Trang 1-9 - 2016
Jonathan Wong, Nathan Davies, Hasan Jeraj, Enric Vilar, Adie Viljoen, Ken Farrington
Endotoxemia is commonly reported in patients receiving haemodialysis and implicated in the pathogenesis of systemic inflammation. The Limulus Amoebocyte Lysate (LAL) assay is the most commonly used blood endotoxin detection assay. Two kinetic variations of the assay are commercially available – the turbidimetric and chromogenic assay, it is unknown which assay is superior for endotoxin detection i...... hiện toàn bộ
Riboflavin along with antibiotics balances reactive oxygen species and inflammatory cytokines and controls Staphylococcus aureus infection by boosting murine macrophage function and regulates inflammation
Springer Science and Business Media LLC - Tập 13 - Trang 1-21 - 2016
Somrita Dey, Biswadev Bishayi
Macrophages serve as intracellular reservoirs of S. aureus. Recent in vitro studies have confirmed high level resistance by S. aureus to macrophage mediated killing and the intracellular persistence of Staphylococci may play an important role in the pathogenesis. Since this localization protects them from both cell-mediated and humoral immune responses, therefore, a successful anti-staphylococcal ...... hiện toàn bộ
Mitochondria protective and anti-apoptotic effects of peripheral benzodiazepine receptor and its ligands on the treatment of asthma in vitro and vivo
Springer Science and Business Media LLC - Tập 21 Số 1
Y. Liu, Zhengze Zhang, Yuewen He, Ruogen Li, Yuhao Zhang, Fei Liu, Yong Wang
Abstract Background Asthma is a prevalent respiratory inflammatory disease. Abnormal apoptosis of bronchial epithelial cells is one of the major factors in the progression of asthma. Peripheral benzodiazepine receptors are highly expressed in bronchial epithelial cells, which act as a component of t...... hiện toàn bộ
Tổng số: 493   
  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • 10