An integrated cytogenetic, radiation-hybrid, and comparative map of dog Chromosome 5Springer Science and Business Media LLC - Tập 12 - Trang 371-375 - 2001
Rachael Thomas, Matthew Breen, Panos Deloukas, Nigel G. Holmes, Matthew M. Binns
The development of a detailed genome map for the domestic dog (Canis familiaris, CFA) is a prerequisite for the continued use of this species as a model system for the study of inherited traits. We present an integrated cytogenetic, radiation-hybrid, and comparative map of dog Chromosome (Chr) 5 (CFA 5). The map comprises 14 gene markers, selected from loci previously mapped within the correspond...... hiện toàn bộ
Deficiency of the tensin2 gene in the ICGN mouse: an animal model for congenital nephrotic syndromeSpringer Science and Business Media LLC - Tập 17 - Trang 407-416 - 2006
A-Ri Cho, Kozue Uchio-Yamada, Takeshi Torigai, Tomomi Miyamoto, Ichiro Miyoshi, Junichiro Matsuda, Tsutomu Kurosawa, Yasuhiro Kon, Atsushi Asano, Nobuya Sasaki, Takashi Agui
The ICGN mouse is a model for nephrotic syndrome (NS) which presents with proteinuria, hyperlipidemia, and edema. In this study we attempted to identify the gene(s) responsible for NS. By analyzing albuminuria in 160 (ICGN × MSM)F1 × ICGN backcross progenies, we found that NS in the ICGN mouse is caused by more than one gene. We then performed a quantitative trait locus (QTL) analysis and detected...... hiện toàn bộ
AgAnimalGenomes: browsers for viewing and manually annotating farm animal genomesSpringer Science and Business Media LLC - Tập 34 - Trang 418-436 - 2023
Deborah A. Triant, Amy T. Walsh, Gabrielle A. Hartley, Bruna Petry, Morgan R. Stegemiller, Benjamin M. Nelson, Makenna M. McKendrick, Emily P. Fuller, Noelle E. Cockett, James E. Koltes, Stephanie D. McKay, Jonathan A. Green, Brenda M. Murdoch, Darren E. Hagen, Christine G. Elsik
Current genome sequencing technologies have made it possible to generate highly contiguous genome assemblies for non-model animal species. Despite advances in genome assembly methods, there is still room for improvement in the delineation of specific gene features in the genomes. Here we present genome visualization and annotation tools to support seven livestock species (bovine, chicken, goat, ho...... hiện toàn bộ
The little (lit) mutation cosegregates with the growth hormone releasing factor receptor on mouse Chromosome 6Springer Science and Business Media LLC - Tập 4 - Trang 555-559 - 1993
Streamson C. Chua, Karen Hennessey, Phillip Zeitler, Rudolph L. Leibel
The little (lit) autosomal recessive mutation in the mouse causes dwarfism due to isolated growth hormone deficiency. The in vitro physiology of pituitary growth hormone release in lit/lit animals suggests that an abnormality in the growth hormone releasing factor (GRF) receptor (Ghrfr) is a very likely candidate for the lit mutation. We mapped Ghrfr to the region around lit on Chromosome (Chr) 6 ...... hiện toàn bộ
The distinguishing sequence characteristics of mouse imprinted genesSpringer Science and Business Media LLC - Tập 13 - Trang 639-645 - 2002
Xiayi Ke, Simon N. Thomas, David O. Robinson, Andrew Collins
Sequence comparison analysis has been carried out for 31 imprinted mouse genes and a set of 150 control genes. The imprinted genes were found to be associated with significantly reduced numbers of short interspersed transposable elements (SINEs), in particular SINE Alu repeats. This is similar to recent analyses of human imprinted genes and supports the suggestion that there is either active selec...... hiện toàn bộ
Mouse chromosome 18Springer Science and Business Media LLC - Tập 1 - Trang S301-S305 - 1991
Muriel T. Davisson, Kenneth R. Johnson, Michael F. Seldin, Hitoshi Suzuki, Tomomasa Watanabe
AnnouncementSpringer Science and Business Media LLC - - 1997