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Impact of Tumor Angiogenesis in Peritoneal Mesothelioma After Radical Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy
Springer Science and Business Media LLC - Tập 16 - Trang 217-222 - 2009
Peritoneal mesothelioma is one of the peritoneal surface malignancies where long-term survival is a reality after cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). Tumor angiogenesis has been shown to be of prognostic significance on survival in mesothelioma. We investigated the impact of survival of patients with peritoneal mesothelioma following CRS and HIPEC to ...... hiện toàn bộ
Nephronectin is Decreased in Metastatic Breast Carcinoma and Related to Metastatic Organs
Springer Science and Business Media LLC - Tập 24 - Trang 679-688 - 2017
Breast cancer causes death mostly due to distant metastasis. During metastasis, cancer cells create new conditions in which normal tissue structure can be disturbed. Nephronectin, which is the primary ligand for α8β1 integrin, plays an important role in kidney development. There are conflicting findings regarding its role in cancer progression and metastasis, especially in breast carcinoma. The ai...... hiện toàn bộ
Susceptibility to Gastric Cancer and Polymorphisms of Insertion/Deletion at the Intron 3 of the XRCC4 and VNTR at the Promoter Region of the XRCC5
Springer Science and Business Media LLC - Tập 21 - Trang 689-693 - 2014
The genes encoding X-ray repair cross-complementing group 4 (XRCC4; OMIM: 194363) and 5 (XRCC5; OMIM: 194364) are involved in repair of DNA double-strand breaks. To investigating the associations between polymorphisms of Insertion/Deletion (I/D, rs28360071) in the intron 3 of the XRCC4 and VNTR in the promoter region of the XRCC5 and risk of gastric cancer, the present study was carried out. We in...... hiện toàn bộ
Investigation of β-catenin and E-cadherin Expression in Dukes B2 Stage Colorectal Cancer with Tissue Microarray Method. Is It a Marker of Metastatic Potential in Rectal Cancer?
Springer Science and Business Media LLC - Tập 18 - Trang 429-437 - 2011
β-catenin and E cadherin are both membrane-associated proteins which are essential regulators and providers of cellular adhesion. In the metastatic cascade of malignant tumours, detachment of tumour cells from each other is a very important step. It has been shown in several tumour types, that reduced expression of these proteins is important. The aim of our study was to clarify the expression pro...... hiện toàn bộ
Spermatocytic Seminoma with Brain Metastasis
Springer Science and Business Media LLC - Tập 23 - Trang 223-224 - 2016
Serotonin and Dopamine Receptor Expression in Solid Tumours Including Rare Cancers
Springer Science and Business Media LLC - Tập 26 - Trang 1539-1547 - 2019
In preclinical studies serotonin stimulates and dopamine inhibits tumour growth and angiogenesis. Information regarding serotonin and dopamine receptor (5-HTR and DRD) expression in human cancers is limited. Therefore, we screened a large tumour set for receptor mRNA overexpression using functional genomic mRNA (FGmRNA) profiling, and we analysed protein expression and location of 5-HTR1B, 5-HTR2B...... hiện toàn bộ
Coagulation and cancer: Implications for diagnosis and management
Springer Science and Business Media LLC - Tập 6 - Trang 301-312 - 2000
Coagulation disorders are a common problem in neoplastic patients and many factors contribute to increase the risk of thromboembolic events in these patients. An hypercoagulable state is induced by malignant cells interacting directly with hemostatic system and activating the coagulation cascade. More sensitive tests to assess an hypercoagulable state in cancer patients have been developed; even t...... hiện toàn bộ
Burkitt’s lymphoma variant of post-transplant lymphoproliferative disease (PTLD)
Springer Science and Business Media LLC - Tập 8 - Trang 105-108 - 2002
The occurrence of posttransplant lymphoproliferative disorder (PTLD) in solid organ allograft recipients can be quite varied in clinical presentation, histopathological characteristics and frequency. A variety of lymphomas can develop as a PTLD although some types appear infrequently and remain poorly understood in this clinical setting. In this report, we describe two cases of Burkitt’s lymphoma ...... hiện toàn bộ
ROCK1-PredictedmicroRNAs Dysregulation Contributes to Tumor Progression in Ewing Sarcoma
Springer Science and Business Media LLC - Tập 26 - Trang 133-139 - 2017
Over the last decade, the rho-associated kinases and several metastasis-associated microRNAs have emerged as important contributors of tumor invasion. However, despite prominence, our understanding of their involvement in the metastatic potential of Ewing Sarcoma (EWS) is incomplete. The expression profiles of ROCK1 or ROCK2 and miR-124-3p, miR-138-5p, miR-139-5p, miR-335-5p and miR-584-5p (all of...... hiện toàn bộ
The Impact of Routine Frozen Section Assessment During Penectomy on Surgical Margin Status and Long-Term Oncologic Outcomes
Springer Science and Business Media LLC - Tập 24 - Trang 947-950 - 2018
No recent studies have focused on assessing the role of intraoperative frozen section assessment (FSA) in the status of surgical margins (SMs) relating to the outcomes of penectomy cases. In this study, we investigated the utility of routine FSA of the SMs in men undergoing penectomy. A retrospective review identified consecutive patients who underwent partial (n = 26) or total (n = 12) penectomy ...... hiện toàn bộ
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