Interferon and interferon-induced cytokines as markers of impending clinical progression in ANA+ individuals without a systemic autoimmune rheumatic disease diagnosisSpringer Science and Business Media LLC - Tập 25 - Trang 1-11 - 2023
Sonya T. Kim, Carolina Muñoz-Grajales, Shannon E. Dunn, Raphael Schneider, Sindhu R. Johnson, Zahi Touma, Zareen Ahmad, Dennisse Bonilla, Eshetu G. Atenafu, Linda T. Hiraki, Arthur Bookman, Joan Wither
Elevated levels of interferons (IFNs) are a characteristic feature of systemic autoimmune rheumatic diseases (SARDs) and may be useful in predicting impending symptomatic progression in anti-nuclear antibody-positive (ANA+) individuals lacking a SARD diagnosis. Typically, these are measured by their effect on gene expression in the blood, which has limited their utility in clinical settings. Here,...... hiện toàn bộ
The vasculature and its role in the damaged and healing tendonSpringer Science and Business Media LLC - Tập 4 - Trang 1-9 - 2002
Steven A Fenwick, Brian L Hazleman, Graham P Riley
Tendon pathology has many manifestations, from spontaneous rupture to chronic tendinitis or tendinosis; the etiology and pathology of each are very different, and poorly understood. Tendon is a comparatively poorly vascularised tissue that relies heavily upon synovial fluid diffusion to provide nutrition. During tendon injury, as with damage to any tissue, there is a requirement for cell infiltrat...... hiện toàn bộ
Childhood Takayasu arteritis: disease course and response to therapySpringer Science and Business Media LLC - Tập 19 - Trang 1-10 - 2017
Florence A. Aeschlimann, Simon W. M. Eng, Shehla Sheikh, Ronald M. Laxer, Diane Hebert, Damien Noone, Marinka Twilt, Christian Pagnoux, Susanne M. Benseler, Rae S. M. Yeung
Takayasu arteritis (TAK) is a large vessel vasculitis that rarely affects children. Data on childhood TAK are scarce. The aim of this study was to analyze the presenting features, course and outcome of children with TAK, compare efficacy of treatment regimens and identify high-risk factors for adverse outcome. A single-center cohort study of consecutive children fulfilling the EULAR/PRINTO/PReS cr...... hiện toàn bộ
Frequency, distribution and immunologic nature of infusion reactions in subjects receiving pegloticase for chronic refractory goutSpringer Science and Business Media LLC - Tập 19 - Trang 1-7 - 2017
Leonard H. Calabrese, Arthur Kavanaugh, Anthony E. Yeo, Peter E. Lipsky
To assess frequency and distribution of infusion reactions (IRs) in responders and nonresponders in randomized clinical trials (RCTs) of intravenous pegloticase and the utility of the National Institute of Allergy and Infectious Disease/Food and Allergy and Anaphylaxis Network (NIAID/FAAN) criteria for identifying anaphylaxis in subjects experiencing IRs. IRs from two RCTs of pegloticase were eval...... hiện toàn bộ
Current and future management approaches for rheumatoid arthritisSpringer Science and Business Media LLC - - 2002
Ferdinand C Breedveld
With the introduction of new disease-modifying antirheumatic drugs (DMARDs) and other therapeutic agents, the management of rheumatoid arthritis (RA) has shifted toward earlier, more aggressive therapy. The ultimate goal is to prevent structural joint damage that leads to pain and functional disability. Early diagnosis of RA is therefore essential, and early DMARD treatment combined with nonsteroi...... hiện toàn bộ
Traditional Chinese medicine formula Bi-Qi capsule alleviates rheumatoid arthritis-induced inflammation, synovial hyperplasia, and cartilage destruction in ratsSpringer Science and Business Media LLC - - 2018
Kai Wang, Dongmei Zhang, Yan Liu, Xuan Wang, Jiantong Zhao, Tao Sun, Tingting Jin, Baoli Li, Janak L. Pathak