Influenza Vaccination and Plasma Concentrations of Theophylline in Patients with Asthma and COPDSpringer Science and Business Media LLC - Tập 9 Số 3 - Trang 161-165 - 1995
Kortabarría, Rafael, Durán, José Antonio, Abadín, José Antonio, Márquez, Francisco
This study attempts to quantify the plasma concentrations of theophylline in patients receiving long term treatment with this drug, and the changes in these concentrations (compared with a control group) when an influenza vaccine was administered. A prospective, open, controlled, comparative pharmacokinetic study was carried out on 34 outpatients (20 males, 14 females). All were receiving long ter...... hiện toàn bộ
Clinical Characteristics and Implications of Bradycardia in COVID-19 Patients Treated with Remdesivir: A Single-Center Retrospective Cohort StudySpringer Science and Business Media LLC - Tập 42 - Trang 763-774 - 2022
Ariyon Schreiber, Justin S. Bauzon, Kavita Batra, Salman Mohammed, Kevin Lee, Nazanin Houshmand, Uyen Pham, Celica Cosme, Kim Inciong, Omar Al-Taweel, Keaton Nasser, Jibran Rana, Chris Sossou, Ariel Go, Dalia Hawwass, Jimmy Diep, Chowdhury H. Ahsan
Remdesivir is an antiviral drug used to treat coronavirus disease 2019 (COVID-19) with a relatively obscure cardiac effect profile. Previous studies have reported bradycardia associated with remdesivir, but few have examined its clinical characteristics. The objective of this study was to investigate remdesivir associated bradycardia and its associated clinical characteristics and outcomes. This i...... hiện toàn bộ
Pharmacokinetics of Alfentanil in Patients Treated with Either Cimetidine or RanitidineSpringer Science and Business Media LLC - Tập 6 - Trang 257-262 - 2012
J. Kienlen, J.-C. Levron, S. Aubas, J.-P. Roustan, J. du Cailar
The pharmacokinetics of alfentanil were studied after single dose intravenous administration of 125 μg/kg to 19 intensive care unit patients who were divided into 3 groups. Group I was given oral antacid, and groups II and III were given, respectively, cimetidine 1200 mg/day IV and ranitidine 300 mg/day IV for 48 hours before administration of alfentanil. Alfentanil plasma concentrations were dete...... hiện toàn bộ
Anthracyclines versus No Anthracyclines in the Neoadjuvant Strategy for HER2+ Breast Cancer: Real-World EvidenceSpringer Science and Business Media LLC - Tập 43 Số 9 - Trang 691-698 - 2023
Inês Soares de Pinho, Paulo Luz, Lucy Alves, Raquel Lopes-Brás, Vanessa Perez Patel, Miguel Esperança-Martins, Lisa Gonçalves, Rui Freitas, Diana Simão, Maria Roldán Galnares, Isabel Fernandes, Silvia Artacho Criado, S. Gamez Casado, J. Baena Cañada, Itzel Tlatilpa Vega, João Guilherme Costa, Ana Sofia Fernandes, Rita Teixeira de Sousa, Luís Costa
Effect of Gemfibrozil on HDL-Associated Serum Paraoxonase Activity and Lipoprotein Profile in Patients with HyperlipidaemiaSpringer Science and Business Media LLC - Tập 19 - Trang 277-282 - 2012
György Paragh, Zoltán Balogh, Ildikó Seres, Mariann Harangi, Judit Boda, Péter Kovács
Objective: Earlier studies pointed out that the high density lipoprotein (HDL)-associated paraoxonase (PON) activity was decreased in patients with hyperlipidaemia compared with healthy age-matched controls. PON can inhibit low density lipoprotein (LDL) oxidation and has an antiatherogenic effect. The aim of the present study was to evaluate the effect of gemfibrozil on serum PON ...... hiện toàn bộ