Combination Aspirin and Clopidogrel for Secondary Prevention of Ischemic StrokeSpringer Science and Business Media LLC - Tập 15 - Trang 348-359 - 2013
Thalia S. Field, Makoto Nakajima, Oscar R. Benavente
Though antiplatelet agents are the mainstay of antithrombotic therapy for secondary prevention of noncardioembolic cerebral ischemic events, the efficacy of combination aspirin and clopidogrel has yet to be clarified by clinical trials. Current evidence suggests that there is no role for long-term combination of aspirin/clopidogrel for secondary stroke prevention. Recent preliminary data from the ...... hiện toàn bộ
Appropriate invasive and conservative treatment approaches for patients with ST-Elevation MISpringer Science and Business Media LLC - Tập 8 - Trang 3-11 - 2006
Michelle O’Donoghue, Marc S. Sabatine
The combination of aspirin, heparin, and fibrinolytics was established in the late 1980s and early 1990s as the foundation for pharmacologic reperfusion therapy for ST-elevation myocardial infarction (STEMI). Since that time, many attempts have been made to improve on this regimen with limited success. In the late 1990s, primary percutaneous coronary intervention emerged as an invasive approach fo...... hiện toàn bộ
Cardiotoxicity of Contemporary Anticancer ImmunotherapySpringer Science and Business Media LLC - Tập 22 Số 12 - Trang 1-15 - 2020
Dal’bo, Natalie, Patel, Rushin, Parikh, Rohan, Shah, Sachin P., Guha, Avirup, Dani, Sourbha S., Ganatra, Sarju
Contemporary anticancer immunotherapy, particularly immune checkpoint inhibitors (ICI) and chimeric antigen receptor (CAR) T cell therapy, has changed the landscape of treatment for patients with a variety of malignancies who historically had a poor prognosis. However, both immune checkpoint inhibitors and CAR T cell therapy are associated with serious cardiovascular adverse effects. As immunother...... hiện toàn bộ
Hypoperfusion and its augmentation in patients with brain ischemiaSpringer Science and Business Media LLC - Tập 5 - Trang 193-199 - 2003
Robert J. Wityk, Lucas Restrepo
Control of hypertension is a well-established goal of the primary and secondary prevention of stroke. However, management of blood pressure in the setting of acute brain ischemia is complicated by the possible effect of blood pressure changes on cerebral perfusion. In acute stroke, patients may have an ischemic penumbra of brain tissue, which has impaired perfusion but which is not irreversibly da...... hiện toàn bộ
Focused Cardiac Ultrasound for the Evaluation of Heart Valve Disease in Resource-Limited SettingsSpringer Science and Business Media LLC - Tập 23 - Trang 1-22 - 2021
Sheila L. Klassen, Maria C.P. Nunes, Amer Johri, Carlene McClanahan, Michael H. Picard
There are many places in the world where comprehensive echocardiography is not available, including remote or rural regions of high-income countries and outside urban centers of low- to middle-income countries. In this review, we discuss the use case for focused cardiac ultrasound (FoCUS) in remote and low-resource settings including its use by non-expert providers as well as its accuracy and limi...... hiện toàn bộ
Kawasaki diseaseSpringer Science and Business Media LLC - Tập 2 - Trang 227-235 - 2000
Jane W. Newburger
Managing Mitral Regurgitation in Heart Failure—Perspectives After COAPTSpringer Science and Business Media LLC - Tập 21 - Trang 1-8 - 2019
Jarrod Betz, Scott M. Lilly, William T. Abraham
Functional mitral regurgitation (MR) in setting of cardiomyopathy causes significant morbidity and worsened survival. Surgical therapies have failed to demonstrate significant overall benefit for functional MR. More recently, major trials utilizing transcatheter therapies for functional MR have been completed and offer new avenues for intervention. This review evaluates and compares 2 major recent...... hiện toàn bộ
Approach to Lower Extremity EdemaSpringer Science and Business Media LLC - Tập 19 - Trang 1-9 - 2017
Elizabeth V. Ratchford, Natalie S. Evans
Lower extremity edema is extremely common among patients seen across multiple specialties. The differential diagnosis is broad and ranges from simple dependent edema to more complex conditions such as chronic venous disease and lymphedema. Several key features from the history and physical exam can assist with the diagnosis. Imaging is rarely necessary at the initial visit unless venous thromboemb...... hiện toàn bộ