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Treatment of Hypertension in Older Persons: What Is the Evidence?
Springer Science and Business Media LLC - Tập 31 - Trang 331-337 - 2014
Evidence for treatment of hypertension in older people is limited to placebo-controlled studies that reduced blood pressure in persons over 60 years who had systolic blood pressure >160 mmHg. Generally, physicians measure blood pressure poorly, failing to look for white coat or masked hypertension, orthostasis, postprandial hypotension, or pseudohypertension. There is evidence that if 24-hour ambu......
Commonly Initiated Opioids and Risk of Fracture Hospitalizations in United States Nursing Homes
Springer Science and Business Media LLC - Tập 35 - Trang 925-936 - 2018
The aim of this study was to estimate the comparative safety of initiating commonly used opioids among older, long-stay United States nursing home residents with fracture hospitalizations. We conducted a new-user retrospective cohort study of nursing home residents initiating short-acting oxycodone, hydrocodone, or tramadol by merging the 2011–2013 Minimum Data Set 3.0 to Medicare hospitalization ......
Diabetic Neuropathy in Elderly Patients
Springer Science and Business Media LLC - Tập 8 - Trang 416-429 - 2012
The prevalence of diabetes mellitus increases markedly with age. Furthermore, advancing age is a strong risk factor for diabetic neuropathy, independent of the duration of diabetes mellitus and glycaemic control. Several biological changes occurring during the aging process may account for the facilitating effect of age on diabetic neuropathy. These include an increase in the production of advance......
Current and Future Treatment Options for Nonexudative and Exudative Age-Related Macular Degeneration
Springer Science and Business Media LLC - Tập 21 - Trang 967-992 - 2012
Age-related macular degeneration (AMD) is the leading cause of irreversible visual loss in the industrialised world. Although relatively simple to diagnose through direct visualisation augmented with rapid sequence fluorescein angiography, treatment has presented a far greater challenge because the true aetiology of AMD is largely unknown. Within the past decade, researchers have introduced many n......
Non-steroidal Anti-inflammatory Drug Use and Risk of Age-Related Macular Degeneration in the California Teachers Study
Springer Science and Business Media LLC - - 2021
Hypertension in the Elderly
Springer Science and Business Media LLC - Tập 22 - Trang 297-314 - 2012
Elderly individuals with hypertension show specific characteristics as a result of advancing arteriosclerosis, a high frequency of isolated systolic hypertension, increased pulse pressure and orthostatic hypotension. The necessity to treat hypertension in the elderly, including isolated systolic hypertension, has been demonstrated in many large-scale intervention trials. Young-old (65–74 years of ......
Comment on: “Recommendations to Prescribe in Complex Older Adults: Results of the CRIteria to Assess Appropriate Medication Use Among Elderly Complex Patients (CRIME) Project”
Springer Science and Business Media LLC - Tập 31 - Trang 327-328 - 2014
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